Effects of Canola Oil and Coconut Oil on Postprandial Metabolism in Older Adults With Increased Cardiometabolic Risk
Cardiovascular Diseases, Metabolic Syndrome
About this trial
This is an interventional basic science trial for Cardiovascular Diseases focused on measuring Postprandial metabolic events
Eligibility Criteria
Inclusion Criteria:
- BMI: 27 - 34,9 kg/m2
- Waist circumference: women ≥ 80 cm, men ≥ 94 cm
- At least two of the following criteria of metabolic syndrome:
Fasting triglycerides in serum: ≥ 150 mg/dl Fasting HDL-Cholesterol in serum: women < 50 mg/dl, men < 40 mg/dl Systolic blood pressure: ≥ 130 mmHg, diastolic blood pressure: ≥ 85 mmHg Fasting glucose in plasma: ≥ 100 mg/dL
Exclusion Criteria:
- Smoking
- Diseases that may impact outcome measures (e.g., thyroid diseases, insulin-dependent diabetes mellitus, impaired renal function, tumors, anemia)
- Intake of immunosuppressives or supplements (e.g., fish oil)
- Participation in another study
Sites / Locations
- University of Bonn
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Experimental
Canola oil high-fat
Coconut oil high-fat
Canola oil low-fat
Coconut oil low-fat
Participants randomized to receive a mixed meal with 50 g canola oil
Participants randomized to receive a mixed meal with 50 g coconut oil
Participants randomized to receive a mixed meal with 25 g canola oil
Participants randomized to receive a mixed meal with 25 g coconut oil