Lidocaine VS Hemodynamic, Metabolic and Hormonal Response
Hemodynamic Response, Acute Appendicitis, Complication of Treatment
About this trial
This is an interventional supportive care trial for Hemodynamic Response focused on measuring multimodal analgesia, lidocaine, intravenous lidocaine, laparoscopic appendectomy, children, pediatric population, adjuvant, metabolic stress response, hormonal response
Eligibility Criteria
Inclusion Criteria:
- ASA physical status class 1E, 2E, 3E;
- Patients undergoing laparoscopic appendectomy.
Exclusion Criteria:
- Allergy to local anesthetics or contraindications for the use of lidocaine;
- ASA physical status class 4E or higher;
- Severe cardiovascular disease;
- Preoperative bradycardia;
- Preoperative atrioventricular block;
- Renal failure;
- Chronic treatment with analgesics;
- Legal guardians' refusal.
Sites / Locations
- University Clinic Centre of Medical University of WarsawRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Lidocaine
Control
1% lidocaine intravenous bolus of 0.15 ml/kg over 5 min before induction of anesthesia followed by lidocaine infusion at 0.15 ml/kg/h intraoperatively will be administered. The infusion will be discontinued before the patients' transfer to the postanesthesia care unit.
0.9% NaCl intravenous bolus of 0.15 ml/kg over 5 min before induction of anesthesia followed by 0.9% NaCl infusion at 0.15 ml/kg/h intraoperatively will be administered. The infusion will be discontinued before the patients' transfer to the postanesthesia care unit.