Fat Grafting in Reducing Recurrence in Patients With Healed Venous Ulcers A Prospective Randomised Clinical Pilot Study
Varicose Ulcer
About this trial
This is an interventional prevention trial for Varicose Ulcer focused on measuring venous, ulcers, fat graft, adipose, stem cells
Eligibility Criteria
Inclusion Criteria:
- Aged 18 years or more.
- Able to provide written informed consent.
- Healed primary venous ulcers (C5 on CEAP classification) of 5cm or less for at least 1 month.
- Ankle-brachial pressure index (ABPI) of 0.8 or more.
Exclusion Criteria:
- Healed recurrent venous ulcers
- Evidence of deep venous occlusion
- Malignancy or immune-suppression
- Malnutrition
- Multi-organ failure
- Pregnancy
Sites / Locations
- Mohamed ElsharkawiRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Fat grafting combined with compression therapy
Compression therapy only
Fat grafting + compression bandages/stockings Fat grafting: For the purposes of this study, the standard technique will be used for all patients General or local anaesthesia. Performed under the supervision of a plastic surgeon. Harvest site will be either abdomen or lower limb. After harvesting fat by liposuction, the lipoaspirate (which contains the ASCs) will be injected at the base of the healed venous ulcer within the same aseptic operative setting. Compression therapy: compression bandages / stockings as per routine practice
Compression therapy: compression bandages / stockings as per routine practice