search
Back to results

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer (MOUNTAINEER-03)

Primary Purpose

Colorectal Neoplasms

Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
tucatinib
trastuzumab
bevacizumab
cetuximab
oxaliplatin
leucovorin
levoleucovorin
fluorouracil
Sponsored by
Seagen Inc.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Colorectal Neoplasms focused on measuring Colorectal Cancer, CRC, Seattle Genetics

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Histologically and/or cytologically confirmed adenocarcinoma of the colon or rectum which is metastatic and/or unresectable

  • Able to provide the most recently available formalin-fixed paraffin-embedded (FFPE) tumor tissue blocks (or freshly sectioned slides) obtained prior to treatment initiation to a central laboratory

    • If archival tissue is not available, a newly-obtained baseline biopsy of an accessible tumor lesion is required within 35 days prior to start of study treatment
  • HER2+ disease as determined by a tissue based assay performed at a central laboratory.
  • Participant has rat sarcoma viral oncogene homolog wild-type (RAS WT) disease as determined by local or central testing

  • Radiographically measurable disease per RECIST v1.1 with:

    • At least one site of disease that is measurable and that has not been previously irradiated, or
    • If the participant has had previous radiation to the target lesion(s), there must be evidence of progression since the radiation
  • Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1

  • CNS Inclusion - based on contrast brain magnetic resonance imaging, participants may have any of the following:

    • No evidence of brain metastases
    • Previously treated brain metastases which are asymptomatic

Exclusion Criteria:

  • Prior systemic anticancer therapy for colorectal cancer (CRC) in the metastatic setting

    • May have received chemotherapy for CRC in the adjuvant setting if it was completed >6 months prior to enrollment
  • Radiation therapy within 14 days prior to enrollment (or within 7 days in the setting of stereotactic radiosurgery)
  • Previous treatment with anti-HER2 therapy
  • Ongoing Grade 3 or higher neuropathy
  • GI perforation within 12 months of enrollment

Sites / Locations

  • Palo Verde Cancer SpecialistsRecruiting
  • Mayo Clinic ArizonaRecruiting
  • Pacific Cancer Medical CenterRecruiting
  • Los Angeles Cancer NetworkRecruiting
  • Kaiser Permanente Southern CaliforniaRecruiting
  • University of Southern CaliforniaRecruiting
  • University of Southern CaliforniaRecruiting
  • Providence Medical Foundation
  • Rocky Mountain Cancer Centers - AuroraRecruiting
  • Mount Sinai Medical Center / FloridaRecruiting
  • Woodlands Medical SpecialistsRecruiting
  • MidAmerica Cancer Center, LLCRecruiting
  • Baptist Health LexingtonRecruiting
  • Norton Cancer InstituteRecruiting
  • Mayo Clinic RochesterRecruiting
  • HealthPartners InstituteRecruiting
  • Memorial Sloan Kettering Cancer CenterRecruiting
  • Duke University Medical CenterRecruiting
  • FirstHealth of the CarolinasRecruiting
  • Gabrail Cancer Center Research, LLC
  • Providence Portland Medical CenterRecruiting
  • Avera Cancer InstituteRecruiting
  • Texas Oncology - Baylor Sammons Cancer CenterRecruiting
  • MD Anderson Cancer Center / University of TexasRecruiting
  • Texas Oncology - McKinneyRecruiting
  • Texas Oncology - Northeast TexasRecruiting
  • Oncology and Hematology Assoc of SW VA DBA Blue Ridge Cancer CareRecruiting
  • Providence Regional Medical Center EverettRecruiting
  • Northwest Cancer Specialists, P.C.Recruiting
  • Instituto Alexander FlemingRecruiting
  • CEMAIC - Centro Medico PrivadoRecruiting
  • Instituto Oncologico de CordobaRecruiting
  • Instituto Medico de la Fundacion Estudios ClinicosRecruiting
  • St Vincent's Hospital MelbourneRecruiting
  • The Alfred HospitalRecruiting
  • Townsville Cancer CenterRecruiting
  • Institut Jules BordetRecruiting
  • Universitair Ziekenhuis AntwerpenRecruiting
  • Hopital de JolimontRecruiting
  • Hospital Nossa Senhora da ConceiçãoRecruiting
  • University of Ottawa / Ottawa General HospitalRecruiting
  • Sunnybrook Health Sciences CentreRecruiting
  • Jewish General HospitalRecruiting
  • Centro de Estudios Clínicos SAGARecruiting
  • Oncocentro APYSRecruiting
  • Beijing Cancer HospitalRecruiting
  • The Second Xiangya Hospital of Central South UniversityRecruiting
  • Hunan Cancer HospitalRecruiting
  • Affiliated Hospital of Chengde Medical UniversityRecruiting
  • 900TH Hospital of Joint Logistics Support ForceRecruiting
  • The Sixth Affiliated Hospital of Sun Yat-sen UniversityRecruiting
  • The Second Affiliated Hospital of Hainan Medical UniversityRecruiting
  • Hainan General HospitalRecruiting
  • The Second Affiliated Hospital of Zhejiang University School of MedicineRecruiting
  • Zhejiang University School of MedicineRecruiting
  • Harbin Medical University Cancer HospitalRecruiting
  • Jinan Central HospitalRecruiting
  • Shandong Cancer HospitalRecruiting
  • The First Hospital Affiliated to Liaoning Medical CollegeRecruiting
  • The First Hospital of Lanzhou UniversityRecruiting
  • Linyi Cancer HospitalRecruiting
  • Meizhou People's Hospital - Guangdong ProvinceRecruiting
  • The First Affiliated Hospital of Nanchang UniversityRecruiting
  • The Second Affiliated Hospital of Nanchang UniversityRecruiting
  • Nanyang Second General HospitalRecruiting
  • Shanghai General HospitalRecruiting
  • The First Hospital of China Medical UniversityRecruiting
  • Liaoning Cancer Hospital and InstituteRecruiting
  • The First Affiliated Hospital of Soochow UniversityRecruiting
  • Shanxi Province Cancer HospitalRecruiting
  • Tangshan People's HospitalRecruiting
  • Hubei Cancer HospitalRecruiting
  • Henan Provincial People's HospitalRecruiting
  • Center Georges Francois LeclercRecruiting
  • Hopital Saint Louis, APHPRecruiting
  • Hopital Saint-AntoineRecruiting
  • CHU Saint Etienne Hopital NordRecruiting
  • Institut de Cancerologie de I'Ouest - Site Saint-HerblainRecruiting
  • Beaumont HospitalRecruiting
  • Chiba Cancer CenterRecruiting
  • National Cancer Center HospitalRecruiting
  • National Hospital Organization Kyushu Cancer CenterRecruiting
  • National Cancer Center Hospital EastRecruiting
  • St. Marianna University School of MedicineRecruiting
  • Kagawa University HospitalRecruiting
  • Kobe City Hospital Organization Kobe City Medical Center General HospitalRecruiting
  • The Cancer Institute Hospital of JFCRRecruiting
  • NHO Shikoku Cancer CenterRecruiting
  • Osaka General Medical Center (Kyuseiki Sogo Iryo C)Recruiting
  • Kindai University HospitalRecruiting
  • National Hospital Organization Hokkaido Cancer CenterRecruiting
  • Osaka Medical and Pharmaceutical University HospitalRecruiting
  • Kanagawa Cancer CenterRecruiting
  • Gachon University Gil Medical CenterRecruiting
  • Korea University Anam HospitalRecruiting
  • Seoul National University HospitalRecruiting
  • Severance Hospital, Yonsei University Health SystemRecruiting
  • Asan Medical Center - OncologyRecruiting
  • Korea University Guro HospitalRecruiting
  • Samsung Medical CenterRecruiting
  • Netherlands Cancer InstituteRecruiting
  • Narodny Onkologicky UstavRecruiting
  • POKO PopradRecruiting
  • Hospital General Universitario AlicanteRecruiting
  • Hospital Universitari Vall d'HebronRecruiting
  • Hospital Clinic de BarcelonaRecruiting
  • Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet)Recruiting
  • Hospital Universitario Ramon y CajalRecruiting
  • Hospital Universitario 12 de OctubreRecruiting
  • Hospital Universitario La PazRecruiting
  • Complejo Hospitalario Universitario de Ourense (CHOU)Recruiting
  • Hospital Universitario Central de AsturiasRecruiting
  • Complejo Hospitalario de NavarraRecruiting
  • Hospital Universitario Marques de ValdecillaRecruiting
  • Hospital Universitario Virgen del RocioRecruiting
  • Consorci Hospital General Universitari de Valencia (CHGUV)Recruiting
  • Universitätsspital ZürichRecruiting
  • Chang Gung Memorial Hospital - KaohsiungRecruiting
  • National Cheng-Kung University HospitalRecruiting
  • Taipei Veterans General HospitalRecruiting
  • National Taiwan University HospitalRecruiting
  • Chang Gung Memorial Hospital - LinkouRecruiting
  • University Hospitals Bristol and Weston NHS Foundation TrustRecruiting
  • Hull University Teaching Hospitals NHS TrustRecruiting
  • Leeds Teaching Hospitals TrustRecruiting
  • Guy's and St Thomas' NHS FoundationRecruiting
  • Imperial College Healthcare NHS TrustRecruiting
  • The Newcastle upon Tyne Hospitals NHS Foundation TrustRecruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Tucatinib Arm

Standard of Care Arm

Arm Description

Tucatinib + trastuzumab + mFOLFOX6

mFOLFOX6 + (bevacizumab OR cetuximab). Either (1) mFOLFOX6, (2) mFOLFOX6 and bevacizumab, or (3) mFOLFOX6 and cetuximab

Outcomes

Primary Outcome Measures

Progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1) by Blinded Independent Central Review (BICR)
The time from the date of randomization to the BICR assessment of disease progression according to RECIST v1.1 or death from any cause

Secondary Outcome Measures

Overall survival (OS)
The time from randomization to death from any cause
Confirmed objective response rate (cORR) per RECIST v1.1 by BICR
The proportion of participants with confirmed complete response (CR) or partial response (PR) according to RECIST v1.1, as assessed by BICR
PFS per RECIST v1.1 by investigator assessment
The time from the date of randomization to the investigator assessment of disease progression according to RECIST v1.1 or death from any cause
cORR per RECIST v1.1 by investigator assessment
The proportion of participants with confirmed CR or PR according to RECIST v1.1, as assessed by investigators
Duration of response (DOR) per RECIST v1.1 by BICR
The time from first documentation of objective response (CR or PR that is subsequently confirmed) to the first documentation of disease progression per RECIST v1.1 or death from any cause
DOR per RECIST v1.1 by investigator assessment
The time from first documentation of objective response (CR or PR that is subsequently confirmed) to the first documentation of disease progression per RECIST v1.1 or death from any cause
Time to second progression or death (PFS2)
The time from randomization to disease progression on the next-line of therapy, or death from any cause
Incidence of adverse events (AEs)
Any untoward medical occurrence in a clinical investigational participant administered a medicinal product and which does not necessarily have a causal relationship with this treatment.
Incidence of dose alterations
Trough concentration (Ctrough)
PK parameter
Change from baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQC30) score
Change from baseline in European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) scores. Scale scores range from 0-100. For functioning and global health status/quality of life (QoL) scales, higher scores indicate better functioning or global health status/quality of life (QoL). For symptom scales, higher scores indicate greater symptom burden.
Time to meaningful change in EORTC QLQ30 score
The time from baseline to the first onset of a ≥10-point changes in European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) scores. Scale scores range from 0-100. For functioning and global health status/QoL scales, higher scores indicate better functioning or global health status/QoL. For symptom scales, higher scores indicate greater symptom burden.

Full Information

First Posted
February 14, 2022
Last Updated
October 23, 2023
Sponsor
Seagen Inc.
Collaborators
Merck Sharp & Dohme LLC
search

1. Study Identification

Unique Protocol Identification Number
NCT05253651
Brief Title
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Acronym
MOUNTAINEER-03
Official Title
An Open-label Randomized Phase 3 Study of Tucatinib in Combination With Trastuzumab and mFOLFOX6 Versus mFOLFOX6 Given With or Without Either Cetuximab or Bevacizumab as First-line Treatment for Subjects With HER2+ Metastatic Colorectal Cancer
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
October 24, 2022 (Actual)
Primary Completion Date
August 31, 2025 (Anticipated)
Study Completion Date
April 30, 2028 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Seagen Inc.
Collaborators
Merck Sharp & Dohme LLC

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This study is being done to find out if tucatinib with other cancer drugs works better than standard of care to treat participants with HER2 positive colorectal cancer. This study will also test what side effects happen when participants take this combination of drugs. A side effect is anything a drug does to the body besides treating your disease. Participants in this study have colorectal cancer that has spread through the body (metastatic) and/or cannot be removed with surgery (unresectable). Participants will be assigned randomly to the tucatinib group or standard of care group. The tucatinib group will get tucatinib, trastuzumab, and mFOLFOX6. The standard of care group will get either: mFOLFOX6 alone, mFOLFOX6 with bevacizumab, or mFOLFOX6 with cetuximab mFOLFOX6 is a combination of multiple drugs. All of the drugs given in this study are used to treat this type of cancer.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Colorectal Neoplasms
Keywords
Colorectal Cancer, CRC, Seattle Genetics

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
400 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Tucatinib Arm
Arm Type
Experimental
Arm Description
Tucatinib + trastuzumab + mFOLFOX6
Arm Title
Standard of Care Arm
Arm Type
Active Comparator
Arm Description
mFOLFOX6 + (bevacizumab OR cetuximab). Either (1) mFOLFOX6, (2) mFOLFOX6 and bevacizumab, or (3) mFOLFOX6 and cetuximab
Intervention Type
Drug
Intervention Name(s)
tucatinib
Other Intervention Name(s)
TUKYSA, ONT-380, ARRY-380
Intervention Description
300mg given by mouth (orally) twice daily
Intervention Type
Drug
Intervention Name(s)
trastuzumab
Other Intervention Name(s)
Herceptin
Intervention Description
8mg/kg loading dose will be given into the vein (IV; intravenously) on Cycle 1 day 1, followed by 6mg/kg given by IV every 3 weeks thereafter.
Intervention Type
Drug
Intervention Name(s)
bevacizumab
Other Intervention Name(s)
Avastin
Intervention Description
5mg/kg given by IV every 2 weeks
Intervention Type
Drug
Intervention Name(s)
cetuximab
Other Intervention Name(s)
Erbitux
Intervention Description
400mg/m2 loading dose will be given by IV on Cycle 1 day 1, followed by 250mg/m2 given by IV weekly
Intervention Type
Drug
Intervention Name(s)
oxaliplatin
Intervention Description
85mg/m2 given by IV every 2 weeks. Component of mFOLFOX6.
Intervention Type
Drug
Intervention Name(s)
leucovorin
Intervention Description
400mg/ m2 given by IV every 2 weeks. Component of mFOLFOX6.
Intervention Type
Drug
Intervention Name(s)
levoleucovorin
Intervention Description
200mg/ m2 given by IV every 2 weeks. May be given in place of leucovorin. Component of mFOLFOX6.
Intervention Type
Drug
Intervention Name(s)
fluorouracil
Intervention Description
400mg/m2 given by IV bolus then 2400mg/m2 given by continuous IV infusion (over 46-48 hours) every 2 weeks. Component of mFOLFOX6.
Primary Outcome Measure Information:
Title
Progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1) by Blinded Independent Central Review (BICR)
Description
The time from the date of randomization to the BICR assessment of disease progression according to RECIST v1.1 or death from any cause
Time Frame
Up to approximately 3 years
Secondary Outcome Measure Information:
Title
Overall survival (OS)
Description
The time from randomization to death from any cause
Time Frame
Up to approximately 6 years
Title
Confirmed objective response rate (cORR) per RECIST v1.1 by BICR
Description
The proportion of participants with confirmed complete response (CR) or partial response (PR) according to RECIST v1.1, as assessed by BICR
Time Frame
Up to approximately 3 years
Title
PFS per RECIST v1.1 by investigator assessment
Description
The time from the date of randomization to the investigator assessment of disease progression according to RECIST v1.1 or death from any cause
Time Frame
Up to approximately 3 years
Title
cORR per RECIST v1.1 by investigator assessment
Description
The proportion of participants with confirmed CR or PR according to RECIST v1.1, as assessed by investigators
Time Frame
Up to approximately 3 years
Title
Duration of response (DOR) per RECIST v1.1 by BICR
Description
The time from first documentation of objective response (CR or PR that is subsequently confirmed) to the first documentation of disease progression per RECIST v1.1 or death from any cause
Time Frame
Up to approximately 3 years
Title
DOR per RECIST v1.1 by investigator assessment
Description
The time from first documentation of objective response (CR or PR that is subsequently confirmed) to the first documentation of disease progression per RECIST v1.1 or death from any cause
Time Frame
Up to approximately 3 years
Title
Time to second progression or death (PFS2)
Description
The time from randomization to disease progression on the next-line of therapy, or death from any cause
Time Frame
Up to approximately 3 years
Title
Incidence of adverse events (AEs)
Description
Any untoward medical occurrence in a clinical investigational participant administered a medicinal product and which does not necessarily have a causal relationship with this treatment.
Time Frame
Through 30 days after the last study treatment; approximately 1 year
Title
Incidence of dose alterations
Time Frame
Through 30 days after the last study treatment; approximately 1 year
Title
Trough concentration (Ctrough)
Description
PK parameter
Time Frame
Approximately 4 months
Title
Change from baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQC30) score
Description
Change from baseline in European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) scores. Scale scores range from 0-100. For functioning and global health status/quality of life (QoL) scales, higher scores indicate better functioning or global health status/quality of life (QoL). For symptom scales, higher scores indicate greater symptom burden.
Time Frame
Through 30-37 days after the last study treatment; approximately 1 year
Title
Time to meaningful change in EORTC QLQ30 score
Description
The time from baseline to the first onset of a ≥10-point changes in European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) scores. Scale scores range from 0-100. For functioning and global health status/QoL scales, higher scores indicate better functioning or global health status/QoL. For symptom scales, higher scores indicate greater symptom burden.
Time Frame
Through 30-37 days after the last study treatment; approximately 1 year

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Histologically and/or cytologically confirmed adenocarcinoma of the colon or rectum which is locally advanced unresectable or metastatic Able to provide the most recently available formalin-fixed paraffin-embedded (FFPE) tumor tissue blocks (or freshly sectioned slides) obtained prior to treatment initiation to a central laboratory If archival tissue is not available, a newly-obtained baseline biopsy of an accessible tumor lesion is required within 35 days prior to start of study treatment HER2+ disease as determined by a tissue based assay performed at a central laboratory. Participant has rat sarcoma viral oncogene homolog wild-type (RAS WT) disease as determined by local or central testing. For central RAS analysis, tissue sample must be analyzed within 1 year of biopsy date. Radiographically measurable disease per RECIST v1.1 with: At least one site of disease that is measurable and that has not been previously irradiated, or If the participant has had previous radiation to the target lesion(s), there must be evidence of progression since the radiation Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1 CNS Inclusion - based on contrast brain magnetic resonance imaging, participants may have any of the following: No evidence of brain metastases Previously treated brain metastases which are asymptomatic Exclusion Criteria: Prior systemic anticancer therapy for colorectal cancer (CRC) in the metastatic setting; note that participants may have received a maximum of 2 doses of mFOLFOX6 in the locally advanced/unresectable or metastatic setting prior to randomization. Note: May have received chemotherapy for CRC in the adjuvant setting if it was completed >6 months prior to enrollment Radiation therapy within 14 days prior to enrollment (or within 7 days in the setting of stereotactic radiosurgery) Previous treatment with anti-HER2 therapy Ongoing Grade 3 or higher neuropathy GI perforation within 12 months of enrollment
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Seagen Trial Information Support
Phone
866-333-7436
Email
clinicaltrials@seagen.com
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Jorge Ramos, DO
Organizational Affiliation
Seagen Inc.
Official's Role
Study Director
Facility Information:
Facility Name
Palo Verde Cancer Specialists
City
Glendale
State/Province
Arizona
ZIP/Postal Code
85304
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Deepak Nayak
Phone
602-978-6255
Email
dnayak@pvcancer.com
First Name & Middle Initial & Last Name & Degree
Amol Rakkar
Facility Name
Mayo Clinic Arizona
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85054
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Raquel Hawkins
Phone
480-574-2602
Email
hawkins.raquel@mayo.edu
First Name & Middle Initial & Last Name & Degree
Tanios Bekaii-Saab
Facility Name
Pacific Cancer Medical Center
City
Anaheim
State/Province
California
ZIP/Postal Code
92801-1830
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Elizabeth Brown
Phone
714-999-1465
Email
elizabethg@pacificcancer.com
First Name & Middle Initial & Last Name & Degree
Veena Charu
Facility Name
Los Angeles Cancer Network
City
Los Angeles
State/Province
California
ZIP/Postal Code
90017
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tania Biswas
Phone
213-977-1214
Email
tania.biswas@lahomg.com
First Name & Middle Initial & Last Name & Degree
Sungwon Rachel Kyung
Facility Name
Kaiser Permanente Southern California
City
Los Angeles
State/Province
California
ZIP/Postal Code
90027
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Susan Nottmeier
Phone
626-372-5186
Email
Susan.L.Nottmeier@kp.org
First Name & Middle Initial & Last Name & Degree
Gary Buchschacher Jr.
Facility Name
University of Southern California
City
Los Angeles
State/Province
California
ZIP/Postal Code
90033
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Heinz-Josef Lenz
Facility Name
University of Southern California
City
Newport Beach
State/Province
California
ZIP/Postal Code
92663
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Heinz-Josef Lenz
Facility Name
Providence Medical Foundation
City
Santa Rosa
State/Province
California
ZIP/Postal Code
95403
Country
United States
Individual Site Status
Completed
Facility Name
Rocky Mountain Cancer Centers - Aurora
City
Denver
State/Province
Colorado
ZIP/Postal Code
80218
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jennifer Hege
Email
jennifer.hege@usoncology.com
First Name & Middle Initial & Last Name & Degree
Allen Cohn
Facility Name
Mount Sinai Medical Center / Florida
City
Miami Beach
State/Province
Florida
ZIP/Postal Code
33140
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ana Lacombe
Phone
305-674-2625 x55860
Email
ana.lacombe@msmc.com
First Name & Middle Initial & Last Name & Degree
Mike Cusnir
Facility Name
Woodlands Medical Specialists
City
Pensacola
State/Province
Florida
ZIP/Postal Code
32503
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Leslie Bellamy
Phone
850-696-4423
Email
lbellamy@woodlandsmed.com
First Name & Middle Initial & Last Name & Degree
Michael Poiesz
Facility Name
MidAmerica Cancer Center, LLC
City
Merriam
State/Province
Kansas
ZIP/Postal Code
66204
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Pam McCann
Phone
913-709-3055
Email
Pam.McCann@amrllc.com
First Name & Middle Initial & Last Name & Degree
Jaswinder Singh
Facility Name
Baptist Health Lexington
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40503
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shelby Gambrell
Phone
859-639-7930
Email
shelby.gambrell@bhsi.com
First Name & Middle Initial & Last Name & Degree
Lee Hicks
Facility Name
Norton Cancer Institute
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40217
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Christine E Johnson
Phone
502-394-3650
Email
Christine.Johnson@nortonhealthcare.org
First Name & Middle Initial & Last Name & Degree
Michael F Driscoll
Facility Name
Mayo Clinic Rochester
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55905
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kathleen Wittenberger
Phone
507-293-2512
Email
Wittenberger.Kathleen@mayo.edu
First Name & Middle Initial & Last Name & Degree
Zhaohui Jin
Facility Name
HealthPartners Institute
City
Saint Louis Park
State/Province
Minnesota
ZIP/Postal Code
55416
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Delaney R Anderson
Phone
952-993-8379
Email
delaney.anderson@parknicollet.com
First Name & Middle Initial & Last Name & Degree
Yan Ji
Facility Name
Memorial Sloan Kettering Cancer Center
City
New York
State/Province
New York
ZIP/Postal Code
10065
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jill Weiss
Phone
646-888-4327
Email
WeissJ2@mskcc.org
First Name & Middle Initial & Last Name & Degree
Andrea Cercek
Facility Name
Duke University Medical Center
City
Durham
State/Province
North Carolina
ZIP/Postal Code
27710
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sabina Wlazlo Cascalherio
Phone
919-613-4812
Email
sabina.wlazlo@duke.edu
First Name & Middle Initial & Last Name & Degree
John H Strickler
Facility Name
FirstHealth of the Carolinas
City
Pinehurst
State/Province
North Carolina
ZIP/Postal Code
28374
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Julie Williams
Phone
910-715-1922
Email
jcwilliams@firsthealth.org
First Name & Middle Initial & Last Name & Degree
Charles Kuzma
Facility Name
Gabrail Cancer Center Research, LLC
City
Canton
State/Province
Ohio
ZIP/Postal Code
44718
Country
United States
Individual Site Status
Completed
Facility Name
Providence Portland Medical Center
City
Portland
State/Province
Oregon
ZIP/Postal Code
97213
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mary McCormick
Phone
503-216-3116
Email
Mary.McCormick@Providence.org
First Name & Middle Initial & Last Name & Degree
Gina M Vaccaro
Facility Name
Avera Cancer Institute
City
Sioux Falls
State/Province
South Dakota
ZIP/Postal Code
57105
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Heidi Nickles
Phone
605-322-3295
Email
heidi.nickles@avera.org
First Name & Middle Initial & Last Name & Degree
Heidi McKean
Facility Name
Texas Oncology - Baylor Sammons Cancer Center
City
Dallas
State/Province
Texas
ZIP/Postal Code
75246
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Dominique Marquez
Phone
214-370-1705
Email
DOMINIQUE.MARQUEZ1@usoncology.com
First Name & Middle Initial & Last Name & Degree
Andrew David McCollum, MD
Facility Name
MD Anderson Cancer Center / University of Texas
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tracy Trevino
Phone
713-792-0622
Email
tltrevino@mdanderson.org
First Name & Middle Initial & Last Name & Degree
Kanwal Raghav
Facility Name
Texas Oncology - McKinney
City
McKinney
State/Province
Texas
ZIP/Postal Code
75071
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Christy DeCastro
Phone
214-491-5845
Email
christy.decastro@usoncology.com
First Name & Middle Initial & Last Name & Degree
Monte Jones
Facility Name
Texas Oncology - Northeast Texas
City
Paris
State/Province
Texas
ZIP/Postal Code
75460
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sue Crumpler
Phone
903-785-0031
Email
sue.crumpler@usoncology.com
First Name & Middle Initial & Last Name & Degree
Sucharu Prakash
Facility Name
Oncology and Hematology Assoc of SW VA DBA Blue Ridge Cancer Care
City
Roanoke
State/Province
Virginia
ZIP/Postal Code
24014
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Natasha R Holt
Phone
540-808-1704
Email
natasha.holt@usoncology.com
First Name & Middle Initial & Last Name & Degree
Mark Kochenderfer
Facility Name
Providence Regional Medical Center Everett
City
Everett
State/Province
Washington
ZIP/Postal Code
98201
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Babita Singh
Phone
425-297-5531
Email
babita.singh@providence.org
First Name & Middle Initial & Last Name & Degree
Amir Mehrvarz Sarshekeh, MD
Facility Name
Northwest Cancer Specialists, P.C.
City
Vancouver
State/Province
Washington
ZIP/Postal Code
98684
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Susan R Papenfuse
Phone
360-449-6521
Email
susan.papenfuse@usoncology.com
First Name & Middle Initial & Last Name & Degree
David Cosgrove
Facility Name
Instituto Alexander Fleming
City
Ciudad Autonoma Buenos Aires
State/Province
Other
ZIP/Postal Code
C1426ANZ
Country
Argentina
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Juan O´Connor
Facility Name
CEMAIC - Centro Medico Privado
City
Cordoba
State/Province
Other
ZIP/Postal Code
X5008HHW
Country
Argentina
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jorge Emilio Salinas
Facility Name
Instituto Oncologico de Cordoba
City
Córdoba
State/Province
Other
ZIP/Postal Code
X5006HBF
Country
Argentina
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Eduardo Richardet
Facility Name
Instituto Medico de la Fundacion Estudios Clinicos
City
Rosario
State/Province
Other
ZIP/Postal Code
S2000DEJ
Country
Argentina
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gabriel Garbaos
Facility Name
St Vincent's Hospital Melbourne
City
Fitzroy
State/Province
Other
ZIP/Postal Code
3065
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sue-Anne McLachlan
Facility Name
The Alfred Hospital
City
Melbourne
State/Province
Other
ZIP/Postal Code
3004
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Benjamin Markman
Facility Name
Townsville Cancer Center
City
Townsville
State/Province
Other
ZIP/Postal Code
4814
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Suresh Varma
Facility Name
Institut Jules Bordet
City
Anderlecht
State/Province
Other
ZIP/Postal Code
B-1070
Country
Belgium
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Francesco Sclafani
Facility Name
Universitair Ziekenhuis Antwerpen
City
Edegem
State/Province
Other
ZIP/Postal Code
2650
Country
Belgium
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hans Prenen, MD
Facility Name
Hopital de Jolimont
City
La Louvière
State/Province
Other
ZIP/Postal Code
7100
Country
Belgium
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Alexandre Dermine
Facility Name
Hospital Nossa Senhora da Conceição
City
Porto Alegre
State/Province
Other
ZIP/Postal Code
91350-200
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gustavo Vasconcelos Alves
Facility Name
University of Ottawa / Ottawa General Hospital
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1H 8L6
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rachel Goodwin
Facility Name
Sunnybrook Health Sciences Centre
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4N 3M5
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sheron Perera
Facility Name
Jewish General Hospital
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H3T 1E2
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Petr Kavan
Facility Name
Centro de Estudios Clínicos SAGA
City
Santiago
State/Province
Other
ZIP/Postal Code
7500653
Country
Chile
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marcelo Adan Garrido Salvo
Facility Name
Oncocentro APYS
City
Viña del Mar
State/Province
Other
ZIP/Postal Code
2520598
Country
Chile
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Alejandro Acevedo Gaete
Facility Name
Beijing Cancer Hospital
City
Beijing
State/Province
Other
ZIP/Postal Code
100142
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lin Shen
Facility Name
The Second Xiangya Hospital of Central South University
City
Changsha
State/Province
Other
ZIP/Postal Code
410011
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yawen Gao
Facility Name
Hunan Cancer Hospital
City
Changsha
State/Province
Other
ZIP/Postal Code
410013
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xianli Yin
Facility Name
Affiliated Hospital of Chengde Medical University
City
Chengde
State/Province
Other
ZIP/Postal Code
067000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qingshan Li
Facility Name
900TH Hospital of Joint Logistics Support Force
City
Fuzhou
State/Province
Other
ZIP/Postal Code
350025
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xi Chen
Facility Name
The Sixth Affiliated Hospital of Sun Yat-sen University
City
Guangzhou
State/Province
Other
ZIP/Postal Code
510655
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yanhong Deng
Facility Name
The Second Affiliated Hospital of Hainan Medical University
City
Haikou
State/Province
Other
ZIP/Postal Code
570100
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Haifeng Lin
Facility Name
Hainan General Hospital
City
Haikou
State/Province
Other
ZIP/Postal Code
570311
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lin Wang
Facility Name
The Second Affiliated Hospital of Zhejiang University School of Medicine
City
Hangzhou
State/Province
Other
ZIP/Postal Code
310009
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ying Yuan
Facility Name
Zhejiang University School of Medicine
City
Hangzhou
State/Province
Other
ZIP/Postal Code
310016
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hongming Pan
Facility Name
Harbin Medical University Cancer Hospital
City
Harbin
State/Province
Other
ZIP/Postal Code
150081
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yuxian Bai
Facility Name
Jinan Central Hospital
City
Jinan
State/Province
Other
ZIP/Postal Code
250013
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Meili Sun
Facility Name
Shandong Cancer Hospital
City
Jinan
State/Province
Other
ZIP/Postal Code
250117
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zuoxing Niu
Facility Name
The First Hospital Affiliated to Liaoning Medical College
City
Jinzhou
State/Province
Other
ZIP/Postal Code
121001
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhitu Zhu
Facility Name
The First Hospital of Lanzhou University
City
Lanzhou
State/Province
Other
ZIP/Postal Code
730000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shoucheng Ma
Facility Name
Linyi Cancer Hospital
City
Linyi
State/Province
Other
ZIP/Postal Code
276000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhen Li
Facility Name
Meizhou People's Hospital - Guangdong Province
City
Meizhou
State/Province
Other
ZIP/Postal Code
514031
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiwen Huang
Facility Name
The First Affiliated Hospital of Nanchang University
City
Nanchang
State/Province
Other
ZIP/Postal Code
330006
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianping Xiong
Facility Name
The Second Affiliated Hospital of Nanchang University
City
Nanchang
State/Province
Other
ZIP/Postal Code
330006
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hua Wang
Facility Name
Nanyang Second General Hospital
City
Nanyang
State/Province
Other
ZIP/Postal Code
473009
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xianzhe Yin
Facility Name
Shanghai General Hospital
City
Shanghai
State/Province
Other
ZIP/Postal Code
200080
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianhua Chen
Facility Name
The First Hospital of China Medical University
City
Shenyang
State/Province
Other
ZIP/Postal Code
110001
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiujuan Qu
Facility Name
Liaoning Cancer Hospital and Institute
City
Shenyang
State/Province
Other
ZIP/Postal Code
110042
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jingdong Zhang
Facility Name
The First Affiliated Hospital of Soochow University
City
Suzhou
State/Province
Other
ZIP/Postal Code
215004
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kai Chen
Facility Name
Shanxi Province Cancer Hospital
City
Taiyuan
State/Province
Other
ZIP/Postal Code
30013
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yusheng Wang
Facility Name
Tangshan People's Hospital
City
Tangshan
State/Province
Other
ZIP/Postal Code
06300
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhiwu Wang
Facility Name
Hubei Cancer Hospital
City
Wuhan
State/Province
Other
ZIP/Postal Code
430000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xinjun Liang
Facility Name
Henan Provincial People's Hospital
City
Zhengzhou
State/Province
Other
ZIP/Postal Code
450003
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shundong Cang
Facility Name
Center Georges Francois Leclerc
City
Dijon
State/Province
Other
ZIP/Postal Code
21000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Francois Ghiringhelli
Facility Name
Hopital Saint Louis, APHP
City
Paris Cedex 10
State/Province
Other
ZIP/Postal Code
75475
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Thomas Aparicio
Facility Name
Hopital Saint-Antoine
City
Paris
State/Province
Other
ZIP/Postal Code
75012
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Thierry Andre
Facility Name
CHU Saint Etienne Hopital Nord
City
Saint-Priest en Jarez
State/Province
Other
ZIP/Postal Code
42270
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jean-Marc Phelip
Facility Name
Institut de Cancerologie de I'Ouest - Site Saint-Herblain
City
St Herblain
State/Province
Other
ZIP/Postal Code
44805
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Judith Raimbourg
Facility Name
Beaumont Hospital
City
Dublin
State/Province
Other
ZIP/Postal Code
D09 AOEA
Country
Ireland
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Adrian Murphy
Facility Name
Chiba Cancer Center
City
Chiba
State/Province
Other
ZIP/Postal Code
260-8717
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Denda Tadamichi
Facility Name
National Cancer Center Hospital
City
Chuo-ku
State/Province
Other
ZIP/Postal Code
104-0045
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Atsuo Takashima
Facility Name
National Hospital Organization Kyushu Cancer Center
City
Fukuoka-shi
State/Province
Other
ZIP/Postal Code
811-1395
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Taito Esaki
Facility Name
National Cancer Center Hospital East
City
Kashiwa-shi
State/Province
Other
ZIP/Postal Code
277-8577
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yoshiaki Nakamura
Facility Name
St. Marianna University School of Medicine
City
Kawasaki-shi
State/Province
Other
ZIP/Postal Code
2168511
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yu Sunakawa
Facility Name
Kagawa University Hospital
City
Kita-gun
State/Province
Other
ZIP/Postal Code
761-0793
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Akihito Tsuji
Facility Name
Kobe City Hospital Organization Kobe City Medical Center General Hospital
City
Kobe-shi
State/Province
Other
ZIP/Postal Code
650-0047
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hisateru Yasui
Facility Name
The Cancer Institute Hospital of JFCR
City
Koto-ku
State/Province
Other
ZIP/Postal Code
135-8550
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kensei Yamaguchi
Facility Name
NHO Shikoku Cancer Center
City
Matsuyama-shi
State/Province
Other
ZIP/Postal Code
791-0280
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tomohiro Nishina
Facility Name
Osaka General Medical Center (Kyuseiki Sogo Iryo C)
City
Osaka-shi
State/Province
Other
ZIP/Postal Code
558-8558
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yoshinori Kagawa
Facility Name
Kindai University Hospital
City
Osakasayama-Shi
State/Province
Other
ZIP/Postal Code
589-8511
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hisato Kawakami
Facility Name
National Hospital Organization Hokkaido Cancer Center
City
Sapporo-shi
State/Province
Other
ZIP/Postal Code
060-8648
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yoshito Komatsu
Facility Name
Osaka Medical and Pharmaceutical University Hospital
City
Takatsuki-shi
State/Province
Other
ZIP/Postal Code
569-8686
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Masahiro Goto
Facility Name
Kanagawa Cancer Center
City
Yokohama
State/Province
Other
ZIP/Postal Code
241-8515
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nozomu Machida
Facility Name
Gachon University Gil Medical Center
City
Incheon
State/Province
Other
ZIP/Postal Code
21565
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
SunJin Sym
Facility Name
Korea University Anam Hospital
City
Seoul
State/Province
Other
ZIP/Postal Code
02841
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
SooHyeon Lee
Facility Name
Seoul National University Hospital
City
Seoul
State/Province
Other
ZIP/Postal Code
03080
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sae-Won Han
Facility Name
Severance Hospital, Yonsei University Health System
City
Seoul
State/Province
Other
ZIP/Postal Code
03722
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Han Sang Kim
Facility Name
Asan Medical Center - Oncology
City
Seoul
State/Province
Other
ZIP/Postal Code
05505
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sun Young Kim
Facility Name
Korea University Guro Hospital
City
Seoul
State/Province
Other
ZIP/Postal Code
08308
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sang Cheul Oh
Facility Name
Samsung Medical Center
City
Seoul
State/Province
Other
ZIP/Postal Code
6351
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Seung Tae Kim
Facility Name
Netherlands Cancer Institute
City
Amsterdam
State/Province
Other
ZIP/Postal Code
1066 WX
Country
Netherlands
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Myriam Chalabi
Facility Name
Narodny Onkologicky Ustav
City
Bratislava
State/Province
Other
ZIP/Postal Code
83100
Country
Slovakia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Stefan Porsok
Facility Name
POKO Poprad
City
Poprad
State/Province
Other
ZIP/Postal Code
058 01
Country
Slovakia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Juraj Beniak
Facility Name
Hospital General Universitario Alicante
City
Alicante
State/Province
Other
ZIP/Postal Code
03010
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ana Lucía Yuste Izquierdo
Facility Name
Hospital Universitari Vall d'Hebron
City
Barcelona
State/Province
Other
ZIP/Postal Code
08035
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Maria Elena Elez Fernandez
Facility Name
Hospital Clinic de Barcelona
City
Barcelona
State/Province
Other
ZIP/Postal Code
08036
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joan Maurel Santasusana
Facility Name
Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet)
City
Barcelona
State/Province
Other
ZIP/Postal Code
08908
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Cristina Santos Vivas
Facility Name
Hospital Universitario Ramon y Cajal
City
Madrid
State/Province
Other
ZIP/Postal Code
28034
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Maria Reyes Ferreiro Monteagudo
Facility Name
Hospital Universitario 12 de Octubre
City
Madrid
State/Province
Other
ZIP/Postal Code
28041
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Cristina Gravalos Castro
Facility Name
Hospital Universitario La Paz
City
Madrid
State/Province
Other
ZIP/Postal Code
28046
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nuria Rodriguez Salas
Facility Name
Complejo Hospitalario Universitario de Ourense (CHOU)
City
Ourense
State/Province
Other
ZIP/Postal Code
32005
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ana Fernandez Montes
Facility Name
Hospital Universitario Central de Asturias
City
Oviedo
State/Province
Other
ZIP/Postal Code
33011
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Paula Jimenez Fonseca
Facility Name
Complejo Hospitalario de Navarra
City
Pamplona
State/Province
Other
ZIP/Postal Code
31008
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ruth Vera Garcia
Facility Name
Hospital Universitario Marques de Valdecilla
City
Santander
State/Province
Other
ZIP/Postal Code
39008
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fernando Rivera Herrero
Facility Name
Hospital Universitario Virgen del Rocio
City
Sevilla
State/Province
Other
ZIP/Postal Code
41013
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Manuel Jesus Valladares Ayerbes
Facility Name
Consorci Hospital General Universitari de Valencia (CHGUV)
City
Valencia
State/Province
Other
ZIP/Postal Code
46014
Country
Spain
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Maria Jose Safont Aguilera
Facility Name
Universitätsspital Zürich
City
Zürich
State/Province
Other
ZIP/Postal Code
8091
Country
Switzerland
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ralph Fritsch
Facility Name
Chang Gung Memorial Hospital - Kaohsiung
City
Kaohsiung City
State/Province
Other
ZIP/Postal Code
83301
Country
Taiwan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hong-Hwa Chen
Facility Name
National Cheng-Kung University Hospital
City
Tainan
State/Province
Other
ZIP/Postal Code
704
Country
Taiwan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yu-Min Yeh
Facility Name
Taipei Veterans General Hospital
City
Taipei City
State/Province
Other
ZIP/Postal Code
112201
Country
Taiwan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hao-Wei Teng
Facility Name
National Taiwan University Hospital
City
Taipei
State/Province
Other
ZIP/Postal Code
10002
Country
Taiwan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kun-Huei Yeh
Facility Name
Chang Gung Memorial Hospital - Linkou
City
Taoyuan
State/Province
Other
ZIP/Postal Code
333
Country
Taiwan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hung-Chih Hsu
Facility Name
University Hospitals Bristol and Weston NHS Foundation Trust
City
Bristol
State/Province
Other
ZIP/Postal Code
BS2 8ED
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Stephen John Falk
Facility Name
Hull University Teaching Hospitals NHS Trust
City
Cottingham
State/Province
Other
ZIP/Postal Code
HU16 5JQ
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Amandeep Dhadda
Facility Name
Leeds Teaching Hospitals Trust
City
Leeds
State/Province
Other
ZIP/Postal Code
LS9 7TF
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jenny Seligmann
Facility Name
Guy's and St Thomas' NHS Foundation
City
London
State/Province
Other
ZIP/Postal Code
SE1 9RT
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Paul Ross
Facility Name
Imperial College Healthcare NHS Trust
City
London
State/Province
Other
ZIP/Postal Code
W12 0HS
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Harpreet Wasan
Facility Name
The Newcastle upon Tyne Hospitals NHS Foundation Trust
City
Newcastle upon Tyne
State/Province
Other
ZIP/Postal Code
NE7 7DN
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Michelle Louise Cunnell

12. IPD Sharing Statement

Learn more about this trial

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

We'll reach out to this number within 24 hrs