Decrease Artery Occlusion by Distal Radial Arterial Cannulation in ACS Patients (DONATION)

The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications. Transradial access (TRA) reduces complications among patients undergoing percutaneous coronary procedures but is reported with the complication of radial artery occlusion (RAO) that limits the radial artery for future needs. Distal radial access (dTRA) has recently gained global popularity as an alternative access route for vascular procedures. Among the benefits of dTRA are the low risk of entry site bleeding complications, the low rate of radial artery occlusion, and improved patient and operator comfort. This study aims to reveal the feasibility and safety of dTRA and routine TRA procedures in acute coronary syndrome patients. The primary endpoints are forearm radical occlusion rate and major adverse cardiovascular events (MACEs) in the two groups, respectively. Investigators will also focus on puncture success in diagnostic and interventional cases, rate of One attempt success, access time, procedure time, crossover rate, contrast dose of patients, fluoroscopy time and dose, and healthcare cost of each group.

Major Adverse Cardiovascular Events, including cardiovascular death, myocardial infarction and heart failure.

Inclusion Criteria: presence of a pulse in the snuffbox Exclusion Criteria: Absence of pulse Ultrasound indication of arterial occlusion or severe calcification Severe forearm artery malformation Patients with severe liver and renal failure, or abnormal coagulation function Established cardiogenic shock History of previous coronary artery bypass grafting and radial artery use. Raynaud's disease in the medical history