Effect of Ultrasound-guided Transversus Abdominis Plane Block After Laparoscopic Bariatric Surgery
Postoperative Nausea and Vomiting, Postoperative Pain
About this trial
This is an interventional prevention trial for Postoperative Nausea and Vomiting focused on measuring Ropivacaine, Transversus abdominis plane block, opioid consumption, Dexamethasone
Eligibility Criteria
Inclusion Criteria:
- Subject is scheduled to undergo Laparoscopic Bariatric Surgery
- Subject's American Society of Anesthesiologists physical status is I-III.
- BMI>35kg/m2
- The subject's parent/legally authorized guardian has given written informed consent to participate
Exclusion Criteria:
- Subject has a diagnosis of renal or liver failure.
- Subject has a diagnosis of mental illness
- Subject is allergy and contraindication to Ropivacaine.
- Subject has a history of chronic pain, a history of alcohol or opioid abuse, pre-existing therapy with opioids, intake of any analgesic drug within 48 hours before surgery.
- Subject has any contraindication for the use
- Subject is pregnant or breast-feeding.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Placebo Comparator
Experimental
Experimental
Normal Saline
Ropivacaine at high concentration
Ropivacaine and dexamethasone
Before the induction of anesthesia, normal saline is used for bilateral transversus abdominis plane block in a volume of 20 mL of each side.
Before the induction of anesthesia, 0.375% Ropivacaine is used for bilateral transversus abdominis plane block in a volume of 20 mL of each side
Before the induction of anesthesia, 0.375% Ropivacaine and 5.0mg dexamethasone are used for bilateral transversus abdominis plane block in a volume of 20 mL of each side