Unified Barlow Protocol (UP) in Cancer Survivors for Cognitive Impairments
Cancer, Breast
About this trial
This is an interventional treatment trial for Cancer, Breast focused on measuring Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP), cognitive impairments, quality of life, anxiety and depression.
Eligibility Criteria
Inclusion Criteria:
- Cancer diagnosis, stages I-III.
- Cancer type: Breast.
- Have received the last chemotherapy session in the last 6 months and a maximum of 6 years of treatment completion.
- Probable or mild to moderate cognitive impairment (score between 26 and 10 points according to the MMSE).
- Ability to be fluent in Spanish.
- Not currently participating in another clinical trial.
- Not currently receiving other psychological treatment
Exclusion Criteria:
- Men and women aged > 70 years.
- Diagnosis of cancer, stage IV or other types of cancer.
- Last chemotherapy session < 6 months or > 6 years.
- No cognitive impairment (MMSE score between 30 and 27 points).
- Diagnosis of mental disorder (including substance abuse) prior to cancer diagnosis.
- Relapse in disease after chemotherapy treatment is completed.
- Neurodevelopmental Disorder Diagnosis.
- Diagnosis of diseases that affect cognitive performance such as: hypertension, cardiac diseases, epilepsy, dementias, multiple sclerosis, functional disorders (fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome, post-concussion syndrome, whiplash syndrome), CNS infections (HIV, encephalitis), metabolic disorders (diabetes, B12 deficiency), obstructive sleep apnea, brain damage (stroke, TBI, CNS cancer) and use of medications / substances that interfere with cognitive function such as pregabalin, gabapentin, topiramate, antidepressants tricyclics, sodium valproate, anticholinergics, methylphenidate, typical antipsychotics.
Sites / Locations
- Hospital Universitario Reina Sofía
- Reina Sofía University HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Experimental
Other
Neuropsychological treatment
Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (PU).
Waitlist group
Combination of different neuropsychological rehabilitation programs
This intervention focuses on a deficit in emotional regulation common in all emotional disorders (ED).
The control group will receive the Adapted Mnesic Cognitive Training (ACTIVE) (Jobe, et al., 2001), as well as the Insight (Posit Science) program (Mahncke et al., 2006) once the interventions in groups 1 and 2 have been completed.