Comparison of Efficacy of Basket and Balloon in the Removal of Pancreatic Duct Stones in Chronic Pancreatitis Under ERCP
Pancreatitis, Chronic, Pancreatic Duct Stone
About this trial
This is an interventional treatment trial for Pancreatitis, Chronic focused on measuring Cholangiopancreatography, Endoscopic Retrograde
Eligibility Criteria
Inclusion Criteria:
- symptomatic adult patients diagnosed with chronic pancreatitis and pancreatic duct stones;
- stones (≤5 mm in diameter) are located in the main pancreatic duct of the pancreatic head/body with dilation of the proximal pancreatic duct.
Exclusion Criteria:
- suspected to have malignant tumors;
- history of pancreatic surgery or gastrojejunostomy (Billroth II);
- bile duct stricture secondary to cholangitis or chronic pancreatitis;
- acute pancreatitis exacerbation or acute exacerbation of chronic pancreatitis (including biliary pancreatitis);
- there is a stent in the main pancreatic duct;
- coagulation dysfunction (INR≥1.5 or platelet count≤50×10^9/L);
- pregnant or breastfeeding women;
- patients who refused to participate in the study.
Sites / Locations
- Changhai Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Treating pancreatic duct stones by using baskets
Treating pancreatic duct stones by using balloons
ERCP will be performed under conscious sedation with intramuscular administration of diazepam 2.5-5.0 mg and pethidine 25-50 mg. If necessary, Endoscopic Sphincterotomy or Endoscopic Papillary Balloon Dilatation will be performed. A dilating bougie or balloon will be used to dilate the stenosis after sphincterotomy. After that, the basket will be used to remove the stones first, and the balloon will replace the basket after 15 minutes to remove any remaining stones. Finally, the effect of the basket will be evaluated.
ERCP will be performed under conscious sedation with intramuscular administration of diazepam 2.5-5.0 mg and pethidine 25-50 mg. If necessary, Endoscopic Sphincterotomy or Endoscopic Papillary Balloon Dilatation will be performed. A dilating bougie or balloon will be used to dilate the stenosis after sphincterotomy. After that, the balloon will be used to remove the stones first, and the basket will replace the balloon after 15 minutes to remove any remaining stones. Finally, the effect of the balloon will be evaluated.