Oxytocin Maintenance Infusion in Labouring Women Undergoing Cesarean Delivery: an Up-down Sequential Allocation Study
Postpartum Hemorrhage
About this trial
This is an interventional treatment trial for Postpartum Hemorrhage focused on measuring Cesarean delivery, oxytocin, uterotonic, pregnancy, labour
Eligibility Criteria
Inclusion Criteria:
• All patients with induced or augmented labour undergoing cesarean delivery under neuraxial anesthesia (at least 3 hours of prior exposure to oxytocin during labour)
Exclusion Criteria:
- All patients who refuse to give written informed consent
- All patients who declare allergy or hypersensitivity to oxytocin
- A history of hypertension and/or severe cardiac disease(s)
- All patients who have contraindications for neuraxial anesthesia
- All patients who will be converted to general anesthesia intraoperatively
- All patients with placenta previa and multiple gestation
Sites / Locations
- Mount Sinai HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm 7
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Oxytocin infusion rate 4 IU/h
Oxytocin infusion rate 6 IU/h
Oxytocin infusion rate 8 IU/h
Oxytocin infusion rate 10 IU/h
Oxytocin infusion rate 12 IU/h
Oxytocin infusion rate 14 IU/h
Oxytocin infusion rate 16 IU/h
The maintenance infusion rate of oxytocin will be 4 IU/h.
The maintenance infusion rate of oxytocin will be 6 IU/h.
The maintenance infusion rate of oxytocin will be 8 IU/h.
The maintenance infusion rate of oxytocin will be 10 IU/h.
The maintenance infusion rate of oxytocin will be 12 IU/h.
The maintenance infusion rate of oxytocin will be 14 IU/h.
The maintenance infusion rate of oxytocin will be 16 IU/h.