Reducing Pain and Opioid Use With CBD

This is an interventional treatment trial for Opioid Use Disorder focused on measuring Opioids, Pain, Cannabidiol, CBD, Cannabis Read More

Inclusion Criteria:

1. Self-reported desire or intent to use cannabidiol to reduce pain and/or opioid use
2. Must be 18 years of age or older.

Exclusion Criteria:

1. Self-reported recreational drug use (other than opioids) in the past 30 days or failed urine screen for cocaine, benzodiazepines, MDMA, sedatives, or methamphetamine;
2. Self-reported current moderate/severe alcohol use, or severe opioid use disorder on the DSM V (unless patient is medically stable and approved by personal physician as well as the Medical Director for the study);
3. Actively seeking or in treatment for or history of any substance use disorder, other than opioid use disorder;
4. Currently being treated for or diagnosed with a moderate, severe, or unstable medical illness (e.g., renal disease, liver disease, cardiovascular disease). If the person has had a recent operation, they must be cleared for study participation by their surgeon or primary care doctor. Study inclusion/exclusion will be evaluated by our medical director when there are questions about applying criteria;

5. Currently taking any of the following medications:

   1. Those known to have a major interaction with Epidiolex (buprenorphine, leflunomide, levomethadyl acetate, lomitapide, mipomersen, pexidartinib, propoxyphene, sodium oxybate, and/or teriflunomide)
   2. Acute treatment with any antiepileptic medications (e.g. clobazam, sodium valproate)
6. Report being treated for bipolar disorder, schizophrenia, dissociative disorders, eating disorders, or any other psychotic or organic mental disorder in the last year.
7. Females of childbearing potential who are pregnant, nursing, or who are not using a reliable form of birth control.
8. Endorsing item 2 on the C-SSRS measure of suicide risk.