Mineralized and Partial Demineralized Dentin Graft Compared to FDBA
Alveolar Bone Loss
About this trial
This is an interventional treatment trial for Alveolar Bone Loss
Eligibility Criteria
Inclusion Criteria:
- Adult patients ≥18 years old
- Able to understand and sign a written informed consent form and willing to fulfil all study requirements.
- Alveolar sockets with intact four-wall architecture.
- Patients with at least a tooth that need to be extracted.
Exclusion Criteria:
- Uncontrolled systemic disease
- Currently smoking >10 cigarettes per day
- History of head and/or neck radiotherapy in the past five years
- Bisphosphonates current use or history of IV bisphosphonate
- Pregnant, expecting to become pregnant, or lactating women.
- Presence of active periodontal disease.
- Teeth that underwent root canal fillings
- Teeth with acute infection at the site of extraction.
- Teeth with periapical infection
Sites / Locations
- University of Oklahoma College of Dentistry Graduate PeriodonticsRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Other
Experimental
Experimental
Freeze-Dried Bone Allograft Control
Mineralized Dentin Graft
Partial-Demineralized Dentin Graft
-Control group (FDBA): extracted teeth will be discarded and sites will be grafted with FDBA.
-Test group I (mineralized tooth graft): extracted teeth will undergo the mineralization process according to the manufacture's guidelines. Procedure will be done in a specialized equipment for tooth graft preparation (Smart Dentin Grinder® (SDG) (KometaBio), and then sites will be grafted. Remaining graft will be stored appropriately for future grafting in the same patient (according to the guidelines)
-Test group II (partial-demineralized tooth graft): extracted teeth will be undergone to partial-demineralized process, according to the manufacture's guidelines. Procedures will be done in a specialized equipment for tooth graft preparation (Smart Dentin Grinder® (SDG) (KometaBio), and then sites will be grafted. Remaining graft will be stored appropriately for future grafting in the same patient (according to the guidelines).