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High-Intensity Interval Training and Fat Mass Losses (RIESLING)

Primary Purpose

Overweight and Obesity, Men

Status

Completed

Phase

Not Applicable

Locations

France

Study Type

Interventional

Intervention

Physical activity

About this trial

This is an interventional treatment trial for Overweight and Obesity focused on measuring cycling, running, high-intensity interval training, fat mass, visceral tissue, health

Eligibility Criteria

18 Years - 65 Years (Adult, Older Adult)MaleAccepts Healthy Volunteers

Inclusion Criteria:

men (18 to 65 years old)
with overweight or obesity (BMI > 25 kg/m2 and ≤ 40 kg/m2)

Exclusion Criteria:

medical contraindications to intense physical activity,
painful joints,
taking ß-blocker

Sites / Locations

CREPS Auvergne Rhône-Alpes / Vichy

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Arm Label

High intensity interval training - BIKE (HIIE BIKE)

High intensity interval training - RUN (HIIE RUN)

Arm Description

10 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (37min30s)

9 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (35min15s)

Outcomes

Primary Outcome Measures

HIIT mode and fat mass change (g)

change of total fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison

HIIT mode and abdominal fat mass change (g)

change of abdominal fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison

Secondary Outcome Measures

Rate of carbohydrate and lipid oxidation (g.min-1) during a sub-maximal exercise by measuring gaz exchange.

Carbohydrate and lipid oxidation rate (g.min-1) during a submaximal exercise before and after the HIIT protocol. HIIT mode comparison.

Full Information

NCT ID

NCT05311800

First Posted

March 16, 2022

Last Updated

February 22, 2023

Sponsor

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques

1. Study Identification

Unique Protocol Identification Number

NCT05311800

Brief Title

High-Intensity Interval Training and Fat Mass Losses

Acronym

RIESLING

Official Title

Effect of Two Isoenergetic Modes of High-Intensity Interval Training on Total and Abdominal Fat Mass Loss in Men With Overweight or Obesity.

Study Type

Interventional

2. Study Status

Record Verification Date

February 2023

Overall Recruitment Status

Completed

Study Start Date

September 1, 2021 (Actual)

Primary Completion Date

July 1, 2022 (Actual)

Study Completion Date

July 1, 2022 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques

4. Oversight

Studies a U.S. FDA-regulated Drug Product

Studies a U.S. FDA-regulated Device Product

Data Monitoring Committee

5. Study Description

Brief Summary

The aims of this study was to compare two isoenergetic HIIT (High-intensity Interval training) programs (cycling vs. running) on body composition, substrate oxidation at rest and during a moderate exercise, muscle functionality, glycaemic control, lipid profile, inflammation, maximal aerobic capacity (VO2max) and gut microbiota composition in men with overweight or obesity. The investigators hypothesized that both programs could decrease total, abdominal and visceral fat mass but due to differences in muscle solicitation, metabolism adaptation and blood flow, and that running could favors greater fat mass losses.

Detailed Description

The first aim of this study was to compare two isoenergetic HIIT programs (cycling vs. running) on body composition in men with overweight or obesity. 20 men with overweight or obesity should completed HIIT program three times a week during twelve weeks. i) High intensity interval training - BIKE (HIIE BIKE) 10 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (37min30s) ii) High intensity interval training - RUN (HIIE RUN) 9 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (35min15s) Body composition will be measured before and after HIIT program by Dual-energy X-ray absorptiometry (DXA).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Overweight and Obesity, Men

Keywords

cycling, running, high-intensity interval training, fat mass, visceral tissue, health

7. Study Design

Primary Purpose

Treatment

Study Phase

Not Applicable

Interventional Study Model

Parallel Assignment

Model Description

2 groups : running vs cycling

Masking

Participant

Masking Description

Data collected on the volunteers will be made anonymous.

Allocation

Randomized

Enrollment

9 (Actual)

8. Arms, Groups, and Interventions

Arm Title

High intensity interval training - BIKE (HIIE BIKE)

Arm Type

Experimental

Arm Description

10 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (37min30s)

Arm Title

High intensity interval training - RUN (HIIE RUN)

Arm Type

Experimental

Arm Description

9 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (35min15s)

Intervention Type

Other

Intervention Name(s)

Physical activity

Intervention Description

Comparison of HIIT mode (running vs cycling)

Primary Outcome Measure Information:

Title

HIIT mode and fat mass change (g)

Description

change of total fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison

Time Frame

At the first and the last training - week 1 and 12

Title

HIIT mode and abdominal fat mass change (g)

Description

change of abdominal fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison

Time Frame

At the first and the last training - week 1 and 12

Secondary Outcome Measure Information:

Title

Rate of carbohydrate and lipid oxidation (g.min-1) during a sub-maximal exercise by measuring gaz exchange.

Description

Carbohydrate and lipid oxidation rate (g.min-1) during a submaximal exercise before and after the HIIT protocol. HIIT mode comparison.

Time Frame

At the first and the last training - week 1 and 12

10. Eligibility

Sex

Male

Minimum Age & Unit of Time

18 Years

Maximum Age & Unit of Time

65 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: men (18 to 65 years old) with overweight or obesity (BMI > 25 kg/m2 and ≤ 40 kg/m2) Exclusion Criteria: medical contraindications to intense physical activity, painful joints, taking ß-blocker

Facility Information:

Facility Name

CREPS Auvergne Rhône-Alpes / Vichy

City

Bellerive-sur-Allier

State/Province

Allier

ZIP/Postal Code

03321

Country

France

12. IPD Sharing Statement

Plan to Share IPD

Learn more about this trial

High-Intensity Interval Training and Fat Mass Losses

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