Impact of Isotretinoin in Different Doses on Quality of Life
Acne Vulgaris
About this trial
This is an interventional treatment trial for Acne Vulgaris
Eligibility Criteria
Inclusion Criteria:
Patients with clinically diagnosed acne vulgaris older than 18 years of age
-
Exclusion Criteria:
Patients having personal or family history of hyperlipidemia. Pregnancy and lactation. Newly married female desiring to get pregnant or using temporary method of contraception.
Patients with a history suggestive of any psychic disturbance -
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Group 1
Group 2
Group 3
Group 4:
:(25)patients will be treated by oral isotretinoin; 0.5 -1 mg/kg/day in two divided doses for 6 months.
:(25) Patients will be treated by oral isotretinoin; 0.5 -1 mg/kg/day for seven days each month for 6 pulses.
:(25) Patients will be treated by oral isotretinoin; 0.1-0.2 mg/kg/day for 6months
(25) Patients will be treated by oral isotretinoin;20mg /day for one month then the dose increased in monthly steps to reach the standard dosing for 6 months