PeRsonalizing the Approach to the Oncologic Frail Individual Through Tailored Assessment and Intervention (PROFIT Study) (PROFIT)
Older Adults, Gastro-Intestinal Cancer, Prostate Cancer
About this trial
This is an interventional treatment trial for Older Adults
Eligibility Criteria
Inclusion Criteria:
1) Older adults (≥65 years) 2) Diagnosed with solid tumors (specifically, prostate, lung, colon, rectal, hepatic-biliary, pancreatic, and esophagus-gastric cancers), an extension of T2, T3, T4, involving or not lymph nodes, and either metastatic or not (M0-1), who might or might not underwent onco-specific treatments or await for new treatments 3) Evidence of functional impact (ECOG≥2) but overall maintained functional status (Barthel≥50) 4) Life expectancy ≥3 months 5) Patients with mild-moderate frailty (G8<14) 5) Willing to provide informed consent to participate.
Exclusion Criteria:
1) Participants with moderate-severe cognitive impairment (Reisberg's Global Deterioration Scale ≥5).
Sites / Locations
- Servei Andorrà d'Atenció Sanitària
- NavarraBiomed
- Parc Sanitari Pere Virgili - Vall d'Hebron Institut de Recerca
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Control group
Intervention group
Treatment as usual. Mainly based on standard physical rehabilitation.
Based on the results of the CGA, a tailored multidisciplinary intervention will be proposed, focused on a multicomponent physical exercise program with nutritional recommendations.