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LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF) (ELEVATE)

Primary Purpose

Idiopathic Pulmonary Fibrosis

Status
Recruiting
Phase
Phase 2
Locations
International
Study Type
Interventional
Intervention
Placebo
Pirfenidone
Deupirfenidone
Sponsored by
PureTech
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Idiopathic Pulmonary Fibrosis focused on measuring IPF, lung fibrosis, respiratory disease

Eligibility Criteria

40 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Key Inclusion Criteria:

  • Treatment naïve patients or those with <6 months of exposure to nintedanib with physician diagnosed IPF based on ATS/ERS/JRS/ALAT 2018 guidelines
  • Idiopathic Pulmonary Fibrosis on HRCT, performed within 12 months of Visit 1 as confirmed by central readers
  • DLCO corrected for Hemoglobin (Hb) [visit 1] ≥ 30% and ≤90% of predicted of normal
  • FVC ≥ 45% of predicted normal

Key Exclusion Criteria:

  • Primary obstructive airway physiology (pre-bronchodilator FEV1/FVC < 0.7 at Visit 1)
  • Known explanation for interstitial lung disease, including but not limited to radiation, sarcoidosis, hypersensitivity pneumonitis, bronchiolitis obliterans organizing pneumonia, human immunodeficiency virus (HIV), viral hepatitis, and cancer
  • Diagnosis of any connective tissue disease, including but not limited to scleroderma/systemic sclerosis, polymyositis/dermatomyositis, systemic lupus erythematosus, and rheumatoid arthritis
  • Major extrapulmonary physiological restriction (e.g., chest wall abnormality, large pleural effusion)

  • Cardiovascular diseases, any of the following:

    • Uncontrolled hypertension, within 3 months of Visit 1
    • Myocardial infarction within 6 months of Visit 1
    • Unstable cardiac angina within 6 months of Visit 1
  • Prior hospitalization for confirmed COVID-19, acute exacerbation of IPF or any lower respiratory tract infection within 3-months of Visit 1

Sites / Locations

  • University of Alabama BirminghamRecruiting
  • University of Southern CaliforniaRecruiting
  • NewportNativeMD, Inc.Recruiting
  • Paradigm Clinical Research Centers, Inc.Recruiting
  • Los Angeles Biomedical Research Institute at Harbor UCLA Medical CenterRecruiting
  • Central Florida Pulmonary GroupRecruiting
  • Accel Research Sites NetworkRecruiting
  • Harmony Medical Research Institute, IncRecruiting
  • Central Florida Pulmonary Group P.A. CFPG - Downtown OrlandoRecruiting
  • Piedmont Healthcare, Inc.Recruiting
  • Accel Research Sites NetworkRecruiting
  • Clinical Research InvestmentsRecruiting
  • Indiana University School of MedicineRecruiting
  • University of Kansas Medical CenterRecruiting
  • Pulmonix
  • Southeastern Research CenterRecruiting
  • University of CincinnatiRecruiting
  • Temple UniversityRecruiting
  • Clinical Trials Center of Middle TennesseeRecruiting
  • Baylor Scott & White Research InstituteRecruiting
  • Metroplex Pulmonary & Sleep Center P.A.
  • Renovatio Clinical - The Woodlands Research CenterRecruiting
  • Pulmonary Associates of RichmondRecruiting
  • TPMG Clinical ResearchRecruiting
  • Medical Institute of Clinical Studies FoundationRecruiting
  • Aprillus Asistencia e InvestigaciónRecruiting
  • CEMER Centro Medico de Enfermedades RespiratoriasRecruiting
  • Instituto de Medicina Respiratoria - IMERRecruiting
  • IERIM Institute of Respiratory Diseases and Medical ResearchRecruiting
  • Respira Salud Clinica IntegralRecruiting
  • Fundacion EnfisemaRecruiting
  • Vistalba Health CenterRecruiting
  • CIMRORecruiting
  • Instituto de Salud RespiratoriaRecruiting
  • Dharma Medical CenterRecruiting
  • Instituto del Buen AireRecruiting
  • Investigaciones en Patologías RespiratoriasRecruiting
  • Clinica Central S.A.Recruiting
  • Maule Clinic
  • CEC Center for Clinical Studies
  • De los Andes ClinicRecruiting
  • Integral Respiratory Center Dr. PavieRecruiting
  • Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic LLCRecruiting
  • Emergency Cardiology Center by Academician G. Chapidze LLCRecruiting
  • LTD Academician Nikoloz Kipshidze Central University ClinicRecruiting
  • LTD Aversi ClinicRecruiting
  • LTD The First Medical CenterRecruiting
  • Athens Medical CenterRecruiting
  • University General Hospital of HeraklionRecruiting
  • University General Hospital of PatrasRecruiting
  • General Hospital of Thessaloniki "G. Papanikolaou"Recruiting
  • Rhythm Heart Institute VadodaraRecruiting
  • Sparsh Super Specialty HospitalRecruiting
  • Mgm Medical College And Hospital, AurangabadRecruiting
  • Government Medical College and Hospital Aurangabad
  • Oriion Citicare Super Specialty HospitalRecruiting
  • Getwell Hospital and Research Institute
  • Govt. General and Chest HospitalRecruiting
  • Apollo Spectra HospitalRecruiting
  • Nil Ratan Sircar Medical College And Hospital, Kolkata
  • Lakeview Heart and Super Specialty HospitalRecruiting
  • The Catholic University Of Korea Bucheon St. Mary's HospitalRecruiting
  • Hanyang University - Myongji HospitalRecruiting
  • Chonbuk National University HospitalRecruiting
  • InJe University Haeundae Paik Hospital
  • Keimyung University - Dongsan Medical CenterRecruiting
  • Chonnam National University HospitalRecruiting
  • CHA Bundang Medical CenterRecruiting
  • Gachon University Gil Medical CenterRecruiting
  • Kyung Hee University HospitalRecruiting
  • Korea University Anam HospitalRecruiting
  • Soon Chun Hyang University Hospital Seoul
  • Hanyang University Seoul HospitalRecruiting
  • Asan Medical CenterRecruiting
  • Samsung Medical CenterRecruiting
  • The Catholic University of Korea, Yeouido St.Mary's HospitalRecruiting
  • Ajou University Hospital
  • Ulsan University HospitalRecruiting
  • Hospital Sultanah Bahiyah
  • Hospital SerdangRecruiting
  • Institut Perubatan RespiratoriRecruiting
  • University Malaya Medical CentreRecruiting
  • Hospital Sultanah Nur Zahirah
  • Hospital Tengku Ampuan AfzanRecruiting
  • Occident Medical Unit
  • Hospital Universitario Dr. José Eleuterio González
  • Integral Health Medical UnitRecruiting
  • CALPULAB
  • Oaxaca Site Management Organization
  • ONCARE GroupRecruiting
  • Philippine General Hospital
  • Philippine Heart Center
  • Lung Center of the Philippines
  • St. Luke's Medical Center - Global CityRecruiting
  • "Victor Babes" Clinical Hospital of Infectious DiseasesRecruiting
  • S.C. Netconsult SRLRecruiting
  • S.C. Lavinia Davidescu Clinic SRLRecruiting
  • Wellness and Clinical Trial CentreRecruiting
  • Durban Lung CentreRecruiting
  • Charlotte Maxeke Johannesburg Academic Hospital
  • Ahmed Kathrada Lenmed Private HospitalRecruiting
  • Netcare Milpark HospitalRecruiting
  • Ryexo Clinical ResearchRecruiting
  • Central Chest Institute Of ThailandRecruiting
  • Songklanagarind HospitalRecruiting

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm Type

Placebo Comparator

Active Comparator

Experimental

Experimental

Arm Label

Placebo

pirfenidone 801 mg TID

LYT-100 550 mg TID

LYT-100 825 mg TID

Arm Description

Placebo oral administration

pirfenidone 801 mg TID oral administration

LYT-100 (Deupirfenidone) 550 mg TID oral administration

LYT-100 (Deupirfenidone) 825 mg TID oral administration

Outcomes

Primary Outcome Measures

Rate of decline in Forced Vital Capacity over 26 weeks
Rate of decline in Forced Vital Capacity (FVC; in mL)

Secondary Outcome Measures

FVC percent predicted change
FVC percent predicted (FVCpp) change from baseline to Week 26
Time to hospitalization or mortality
Time to hospitalization or mortality due to respiratory cause through 26 weeks
Time to IPF progression
Time to IPF progression through 26 weeks, as defined by a decline in FVC% of 5% or greater or death

Full Information

First Posted
April 2, 2022
Last Updated
October 20, 2023
Sponsor
PureTech
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1. Study Identification

Unique Protocol Identification Number
NCT05321420
Brief Title
LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Acronym
ELEVATE
Official Title
A Randomized Double-blind, Four-Arm Active and Placebo-controlled Dose-Finding Trial to Evaluate the Efficacy, Tolerability, Safety and Dose Response of LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
July 29, 2022 (Actual)
Primary Completion Date
December 2023 (Anticipated)
Study Completion Date
March 2024 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
PureTech

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This study a randomized, double-blind, four arm study to evaluate the safety and efficacy of LYT-100 compared to pirfenidone or placebo in adults with Idiopathic Pulmonary Fibrosis.
Detailed Description
This study is a randomized, double-blind, being conducted at centers globally to evaluate the safety and efficacy of LYT-100 compared to pirfenidone or placebo in 240 treatment naïve adult patients with IPF ≥ 40 years in age. Patients will be randomized in a ratio of 1:1:1:1 to receive treatment of LYT-100, pirfenidone, or placebo to be taken daily for up to 183 days (26 week treatment period) with the primary outcome of Rate of decline in Forced Vital Capacity (FVC; in mL) over 26 weeks. Secondary endpoints, including spirometry, inflammatory biomarkers, and patient-reported outcomes will also be evaluated.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Idiopathic Pulmonary Fibrosis
Keywords
IPF, lung fibrosis, respiratory disease

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 2
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
240 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Placebo
Arm Type
Placebo Comparator
Arm Description
Placebo oral administration
Arm Title
pirfenidone 801 mg TID
Arm Type
Active Comparator
Arm Description
pirfenidone 801 mg TID oral administration
Arm Title
LYT-100 550 mg TID
Arm Type
Experimental
Arm Description
LYT-100 (Deupirfenidone) 550 mg TID oral administration
Arm Title
LYT-100 825 mg TID
Arm Type
Experimental
Arm Description
LYT-100 (Deupirfenidone) 825 mg TID oral administration
Intervention Type
Drug
Intervention Name(s)
Placebo
Intervention Description
placebo
Intervention Type
Drug
Intervention Name(s)
Pirfenidone
Intervention Description
pirfenidone 801 mg TID
Intervention Type
Drug
Intervention Name(s)
Deupirfenidone
Intervention Description
Deupirfenidone
Primary Outcome Measure Information:
Title
Rate of decline in Forced Vital Capacity over 26 weeks
Description
Rate of decline in Forced Vital Capacity (FVC; in mL)
Time Frame
26 weeks
Secondary Outcome Measure Information:
Title
FVC percent predicted change
Description
FVC percent predicted (FVCpp) change from baseline to Week 26
Time Frame
Baseline to Week 26
Title
Time to hospitalization or mortality
Description
Time to hospitalization or mortality due to respiratory cause through 26 weeks
Time Frame
26 weeks
Title
Time to IPF progression
Description
Time to IPF progression through 26 weeks, as defined by a decline in FVC% of 5% or greater or death
Time Frame
26 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
40 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Key Inclusion Criteria: Treatment naïve patients or those with <6 months of exposure to nintedanib with physician diagnosed IPF based on ATS/ERS/JRS/ALAT 2018 guidelines Idiopathic Pulmonary Fibrosis on HRCT, performed within 12 months of Visit 1 as confirmed by central readers DLCO corrected for Hemoglobin (Hb) [visit 1] ≥ 30% and ≤90% of predicted of normal FVC ≥ 45% of predicted normal Key Exclusion Criteria: Primary obstructive airway physiology (pre-bronchodilator FEV1/FVC < 0.7 at Visit 1) Known explanation for interstitial lung disease, including but not limited to radiation, sarcoidosis, hypersensitivity pneumonitis, bronchiolitis obliterans organizing pneumonia, human immunodeficiency virus (HIV), viral hepatitis, and cancer Diagnosis of any connective tissue disease, including but not limited to scleroderma/systemic sclerosis, polymyositis/dermatomyositis, systemic lupus erythematosus, and rheumatoid arthritis Major extrapulmonary physiological restriction (e.g., chest wall abnormality, large pleural effusion) Cardiovascular diseases, any of the following: Uncontrolled hypertension, within 3 months of Visit 1 Myocardial infarction within 6 months of Visit 1 Unstable cardiac angina within 6 months of Visit 1 Prior hospitalization for confirmed COVID-19, acute exacerbation of IPF or any lower respiratory tract infection within 3-months of Visit 1
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Wassim Fares, MD
Phone
617-226-4813
Email
clinicaltrials@puretechhealth.com
First Name & Middle Initial & Last Name or Official Title & Degree
Sarah Santipadri
Phone
617-226-4813
Email
clinicaltrials@puretechhealth.com
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Wassim Fares, MD
Organizational Affiliation
PureTech
Official's Role
Study Director
Facility Information:
Facility Name
University of Alabama Birmingham
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35294
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Southern California
City
Los Angeles
State/Province
California
ZIP/Postal Code
90089
Country
United States
Individual Site Status
Recruiting
Facility Name
NewportNativeMD, Inc.
City
Newport Beach
State/Province
California
ZIP/Postal Code
92663
Country
United States
Individual Site Status
Recruiting
Facility Name
Paradigm Clinical Research Centers, Inc.
City
Redding
State/Province
California
ZIP/Postal Code
96001
Country
United States
Individual Site Status
Recruiting
Facility Name
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center
City
Torrance
State/Province
California
ZIP/Postal Code
90502
Country
United States
Individual Site Status
Recruiting
Facility Name
Central Florida Pulmonary Group
City
Altamonte Springs
State/Province
Florida
ZIP/Postal Code
32701
Country
United States
Individual Site Status
Recruiting
Facility Name
Accel Research Sites Network
City
DeLand
State/Province
Florida
ZIP/Postal Code
32720
Country
United States
Individual Site Status
Recruiting
Facility Name
Harmony Medical Research Institute, Inc
City
Hialeah
State/Province
Florida
ZIP/Postal Code
33016
Country
United States
Individual Site Status
Recruiting
Facility Name
Central Florida Pulmonary Group P.A. CFPG - Downtown Orlando
City
Orlando
State/Province
Florida
ZIP/Postal Code
32803
Country
United States
Individual Site Status
Recruiting
Facility Name
Piedmont Healthcare, Inc.
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30309
Country
United States
Individual Site Status
Recruiting
Facility Name
Accel Research Sites Network
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30030
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Research Investments
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30030
Country
United States
Individual Site Status
Recruiting
Facility Name
Indiana University School of Medicine
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46202
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Kansas Medical Center
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Individual Site Status
Recruiting
Facility Name
Pulmonix
City
Greensboro
State/Province
North Carolina
ZIP/Postal Code
27403
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Southeastern Research Center
City
Winston-Salem
State/Province
North Carolina
ZIP/Postal Code
27103
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Cincinnati
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45267
Country
United States
Individual Site Status
Recruiting
Facility Name
Temple University
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19140
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Trials Center of Middle Tennessee
City
Franklin
State/Province
Tennessee
ZIP/Postal Code
37067
Country
United States
Individual Site Status
Recruiting
Facility Name
Baylor Scott & White Research Institute
City
Dallas
State/Province
Texas
ZIP/Postal Code
75204
Country
United States
Individual Site Status
Recruiting
Facility Name
Metroplex Pulmonary & Sleep Center P.A.
City
McKinney
State/Province
Texas
ZIP/Postal Code
75069
Country
United States
Individual Site Status
Not yet recruiting
Facility Name
Renovatio Clinical - The Woodlands Research Center
City
The Woodlands
State/Province
Texas
ZIP/Postal Code
77380
Country
United States
Individual Site Status
Recruiting
Facility Name
Pulmonary Associates of Richmond
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23230
Country
United States
Individual Site Status
Recruiting
Facility Name
TPMG Clinical Research
City
Williamsburg
State/Province
Virginia
ZIP/Postal Code
23188
Country
United States
Individual Site Status
Recruiting
Facility Name
Medical Institute of Clinical Studies Foundation
City
Rosario
State/Province
Santa Fe
ZIP/Postal Code
2000
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Aprillus Asistencia e Investigación
City
Buenos Aires
ZIP/Postal Code
1406
Country
Argentina
Individual Site Status
Recruiting
Facility Name
CEMER Centro Medico de Enfermedades Respiratorias
City
Buenos Aires
ZIP/Postal Code
1602
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Instituto de Medicina Respiratoria - IMER
City
Córdoba
ZIP/Postal Code
X5003DCE
Country
Argentina
Individual Site Status
Recruiting
Facility Name
IERIM Institute of Respiratory Diseases and Medical Research
City
Florencio Varela
ZIP/Postal Code
1888
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Respira Salud Clinica Integral
City
Godoy Cruz
ZIP/Postal Code
5501
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Fundacion Enfisema
City
Mar Del Plata
ZIP/Postal Code
7600
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Vistalba Health Center
City
Mendoza
ZIP/Postal Code
1428
Country
Argentina
Individual Site Status
Recruiting
Facility Name
CIMRO
City
Mendoza
ZIP/Postal Code
5600
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Instituto de Salud Respiratoria
City
Mendoza
ZIP/Postal Code
M5500CCG
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Dharma Medical Center
City
Mendoza
ZIP/Postal Code
M5500
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Instituto del Buen Aire
City
Santa Fe
ZIP/Postal Code
3000
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Investigaciones en Patologías Respiratorias
City
Tucuman
ZIP/Postal Code
4000
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Clinica Central S.A.
City
Villa Regina
ZIP/Postal Code
8336
Country
Argentina
Individual Site Status
Recruiting
Facility Name
Maule Clinic
City
Maule
ZIP/Postal Code
3530000
Country
Chile
Individual Site Status
Not yet recruiting
Facility Name
CEC Center for Clinical Studies
City
Santiago
ZIP/Postal Code
7550000
Country
Chile
Individual Site Status
Not yet recruiting
Facility Name
De los Andes Clinic
City
Santiago
ZIP/Postal Code
7550000
Country
Chile
Individual Site Status
Recruiting
Facility Name
Integral Respiratory Center Dr. Pavie
City
Valparaiso
Country
Chile
Individual Site Status
Recruiting
Facility Name
Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic LLC
City
Tbilisi
ZIP/Postal Code
0144
Country
Georgia
Individual Site Status
Recruiting
Facility Name
Emergency Cardiology Center by Academician G. Chapidze LLC
City
Tbilisi
ZIP/Postal Code
0159
Country
Georgia
Individual Site Status
Recruiting
Facility Name
LTD Academician Nikoloz Kipshidze Central University Clinic
City
Tbilisi
ZIP/Postal Code
0159
Country
Georgia
Individual Site Status
Recruiting
Facility Name
LTD Aversi Clinic
City
Tbilisi
ZIP/Postal Code
0160
Country
Georgia
Individual Site Status
Recruiting
Facility Name
LTD The First Medical Center
City
Tbilisi
ZIP/Postal Code
0180
Country
Georgia
Individual Site Status
Recruiting
Facility Name
Athens Medical Center
City
Athens
ZIP/Postal Code
15125
Country
Greece
Individual Site Status
Recruiting
Facility Name
University General Hospital of Heraklion
City
Heraklion
ZIP/Postal Code
71110
Country
Greece
Individual Site Status
Recruiting
Facility Name
University General Hospital of Patras
City
Patras
ZIP/Postal Code
26504
Country
Greece
Individual Site Status
Recruiting
Facility Name
General Hospital of Thessaloniki "G. Papanikolaou"
City
Thessaloniki
ZIP/Postal Code
57010
Country
Greece
Individual Site Status
Recruiting
Facility Name
Rhythm Heart Institute Vadodara
City
Vadodara
State/Province
Gujarat
ZIP/Postal Code
390022
Country
India
Individual Site Status
Recruiting
Facility Name
Sparsh Super Specialty Hospital
City
Bengaluru
State/Province
Karnataka
ZIP/Postal Code
560001
Country
India
Individual Site Status
Recruiting
Facility Name
Mgm Medical College And Hospital, Aurangabad
City
Aurangabad
State/Province
Maharashtra
ZIP/Postal Code
431003
Country
India
Individual Site Status
Recruiting
Facility Name
Government Medical College and Hospital Aurangabad
City
Aurangabad
State/Province
Maharashtra
ZIP/Postal Code
431004
Country
India
Individual Site Status
Not yet recruiting
Facility Name
Oriion Citicare Super Specialty Hospital
City
Aurangabad
State/Province
Maharashtra
ZIP/Postal Code
431005
Country
India
Individual Site Status
Recruiting
Facility Name
Getwell Hospital and Research Institute
City
Nagpur
State/Province
Maharashtra
ZIP/Postal Code
440012
Country
India
Individual Site Status
Not yet recruiting
Facility Name
Govt. General and Chest Hospital
City
Hyderabad
State/Province
Telangana
ZIP/Postal Code
500038
Country
India
Individual Site Status
Recruiting
Facility Name
Apollo Spectra Hospital
City
Kanpur
State/Province
Uttar Pradesh
ZIP/Postal Code
208001
Country
India
Individual Site Status
Recruiting
Facility Name
Nil Ratan Sircar Medical College And Hospital, Kolkata
City
Kolkata
State/Province
West Bengal
ZIP/Postal Code
700014
Country
India
Individual Site Status
Not yet recruiting
Facility Name
Lakeview Heart and Super Specialty Hospital
City
Belagave
Country
India
Individual Site Status
Recruiting
Facility Name
The Catholic University Of Korea Bucheon St. Mary's Hospital
City
Bucheon-si
State/Province
Gyeonggi-do
ZIP/Postal Code
14647
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Hanyang University - Myongji Hospital
City
Goyang-si
State/Province
Gyeonggi-do
ZIP/Postal Code
10475
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Chonbuk National University Hospital
City
Jeonju
State/Province
Jeollabuk-do
ZIP/Postal Code
54907
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
InJe University Haeundae Paik Hospital
City
Busan
ZIP/Postal Code
48108
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Name
Keimyung University - Dongsan Medical Center
City
Daegu
ZIP/Postal Code
42601
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Chonnam National University Hospital
City
Gwangju
ZIP/Postal Code
61469
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
CHA Bundang Medical Center
City
Gyeonggi-do
ZIP/Postal Code
13496
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Gachon University Gil Medical Center
City
Incheon
ZIP/Postal Code
21565
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Kyung Hee University Hospital
City
Seoul
ZIP/Postal Code
02447
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Korea University Anam Hospital
City
Seoul
ZIP/Postal Code
02841
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Soon Chun Hyang University Hospital Seoul
City
Seoul
ZIP/Postal Code
04401
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Name
Hanyang University Seoul Hospital
City
Seoul
ZIP/Postal Code
04763
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Asan Medical Center
City
Seoul
ZIP/Postal Code
05505
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Samsung Medical Center
City
Seoul
ZIP/Postal Code
06351
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
The Catholic University of Korea, Yeouido St.Mary's Hospital
City
Seoul
ZIP/Postal Code
07345
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Ajou University Hospital
City
Suwon
ZIP/Postal Code
16499
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Name
Ulsan University Hospital
City
Ulsan
ZIP/Postal Code
44033
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Name
Hospital Sultanah Bahiyah
City
Alor Setar
State/Province
Kedah
ZIP/Postal Code
05460
Country
Malaysia
Individual Site Status
Not yet recruiting
Facility Name
Hospital Serdang
City
Kajang
Country
Malaysia
Individual Site Status
Recruiting
Facility Name
Institut Perubatan Respiratori
City
Kuala Lumpur
Country
Malaysia
Individual Site Status
Recruiting
Facility Name
University Malaya Medical Centre
City
Kuala Lumpur
Country
Malaysia
Individual Site Status
Recruiting
Facility Name
Hospital Sultanah Nur Zahirah
City
Kuala Terengganu
ZIP/Postal Code
93586
Country
Malaysia
Individual Site Status
Not yet recruiting
Facility Name
Hospital Tengku Ampuan Afzan
City
Kuantan
Country
Malaysia
Individual Site Status
Recruiting
Facility Name
Occident Medical Unit
City
Zapopan
State/Province
Jalisco
ZIP/Postal Code
44220
Country
Mexico
Individual Site Status
Not yet recruiting
Facility Name
Hospital Universitario Dr. José Eleuterio González
City
Monterrey
State/Province
Nuevo Leon
ZIP/Postal Code
64460
Country
Mexico
Individual Site Status
Not yet recruiting
Facility Name
Integral Health Medical Unit
City
San Nicolas de los Garza
State/Province
Nuevo Leon
ZIP/Postal Code
66465
Country
Mexico
Individual Site Status
Recruiting
Facility Name
CALPULAB
City
Calpulalpan
ZIP/Postal Code
90204
Country
Mexico
Individual Site Status
Not yet recruiting
Facility Name
Oaxaca Site Management Organization
City
Oaxaca
ZIP/Postal Code
68000
Country
Mexico
Individual Site Status
Not yet recruiting
Facility Name
ONCARE Group
City
San Pedro Garza Garcia
ZIP/Postal Code
66220
Country
Mexico
Individual Site Status
Recruiting
Facility Name
Philippine General Hospital
City
Manila
ZIP/Postal Code
1000
Country
Philippines
Individual Site Status
Not yet recruiting
Facility Name
Philippine Heart Center
City
Manila
ZIP/Postal Code
1100
Country
Philippines
Individual Site Status
Not yet recruiting
Facility Name
Lung Center of the Philippines
City
Quezon City
ZIP/Postal Code
1100
Country
Philippines
Individual Site Status
Not yet recruiting
Facility Name
St. Luke's Medical Center - Global City
City
Taguig
ZIP/Postal Code
1634
Country
Philippines
Individual Site Status
Recruiting
Facility Name
"Victor Babes" Clinical Hospital of Infectious Diseases
City
Craiova
ZIP/Postal Code
200446
Country
Romania
Individual Site Status
Recruiting
Facility Name
S.C. Netconsult SRL
City
Iaşi
ZIP/Postal Code
700141
Country
Romania
Individual Site Status
Recruiting
Facility Name
S.C. Lavinia Davidescu Clinic SRL
City
Oradea
ZIP/Postal Code
410163
Country
Romania
Individual Site Status
Recruiting
Facility Name
Wellness and Clinical Trial Centre
City
Cape Town
ZIP/Postal Code
7441
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Durban Lung Centre
City
Durban
ZIP/Postal Code
4051
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Charlotte Maxeke Johannesburg Academic Hospital
City
Johannesburg
ZIP/Postal Code
2193
Country
South Africa
Individual Site Status
Not yet recruiting
Facility Name
Ahmed Kathrada Lenmed Private Hospital
City
Johannesburg
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Netcare Milpark Hospital
City
Parktown
ZIP/Postal Code
2193
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Ryexo Clinical Research
City
Pretoria
ZIP/Postal Code
0084
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Central Chest Institute Of Thailand
City
Nonthaburi
Country
Thailand
Individual Site Status
Recruiting
Facility Name
Songklanagarind Hospital
City
Songkhla
Country
Thailand
Individual Site Status
Recruiting

12. IPD Sharing Statement

Plan to Share IPD
No
Links:
URL
http://www.elevateipf.com
Description
Recruiting website for patients in the United States

Learn more about this trial

LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

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