The Effects of Dietary Changes on Gut-bacteria and Fibromyalgia Symptoms
Fibromyalgia, Diet, Gluten-Free
About this trial
This is an interventional treatment trial for Fibromyalgia
Eligibility Criteria
Inclusion Criteria:
- Women over the age of 18, diagnosed with FM.
- Chronic widespread pain index >= 9 and pain intensity >= 6.
- Able to read and write in either French or English.
Exclusion Criteria:
- Any major illness (e.g. malignancy, active inflammatory disease, metabolic disease, etc.)
- Inflammatory bowel disease.
- Severe depression (HADS score for depression > 10).
- Current use of LFD or GFD.
- Pregnancy
- Vegan diet
The inclusion/exclusion criteria were set to reduce the risk of confounding factors that could affect gut microbiota composition. To date, information on microbiome alterations in individuals with fibromyalgia is only available for female patients, and thus recruitment will be limited to women.
Sites / Locations
- Alan Edwards Pain Management Unit - Montreal General Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Other
Low-FODMAP Diet
Gluten-Free Diet
Control
Participants will be instructed to maintain their usual diet, while eliminating FODMAPs (A subgroup of carbohydrates are considered fermentable, given the lack of suitable hydrolase enzymes in the colon, required for their digestion and absorption, thus making them available for fermentation).
Participants will be instructed to maintain their usual diet, while eliminating all dietary gluten.
Patients of this group will be asked to adhere to their regular, daily diet.