Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency Band (ZOV)

Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency Band

Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency Band

In this study, the investigators will research the efficacy of a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes.

Stuttering is a speech disorder that affects more than 70 million people worldwide, limiting their ability to communicate and socialize. During recent decades, several studies have demonstrated a link between stuttering and a deficit of β EEG spectral power. In this study, the investigators will research the efficacy of a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes. Participants are adults with stuttering and without speech disfluencies from the control group will expose to euphonic binaural stimuli for 5 minutes. The brain electrical activity patterns (EEG) and ECG bio-signals will record prior to, during, and after exposure.

The arm will use a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes to improve stuttering symptoms. The total length of the audio stimuli is 5 minutes.

ZOV.ai is a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes to improve stuttering symptoms

The total number of repetitions, blocks and prolongations during the speech (assessed by speech therapist) measured before, just after and 10 minutes after auditory stimulation

The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation

Stress Level changes assessed by ECG HRV measurements before, just after and 10 minutes after auditory stimulation

The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation

Average of RR-intervals array assessed by ECG HRV measurements before, just after and 10 minutes after auditory stimulation

The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation

Total Power of RR-intervals array spectrogram assessed by ECG HRV measurements before, just after and 10 minutes after auditory stimulation

The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation

SDNN value of RR-intervals array assessed by ECG HRV measurements before, just after and 10 minutes after auditory stimulation

The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation

RMSSD value of RR-intervals array assessed by ECG HRV measurements before, just after and 10 minutes after auditory stimulation

The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation

Electrical spectral density in beta frequency range of brain activity measured before, just after and 10 minutes after auditory stimulation

The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation

Inclusion Criteria: Adults with stuttering (stammering) symptoms; Exclusion Criteria: Hearing disabilities; Applying other drugs or devices simultaneously;