Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe
Bronchi--Diseases, Lung Diseases, Obstructive, Lesions Mass
About this trial
This is an interventional other trial for Bronchi--Diseases
Eligibility Criteria
Inclusion Criteria:
- Patient clinically meets indication for peripheral lung nodule biopsy and has been scheduled for robotic bronchoscopy.
Lesion Criteria:
- Pulmonary nodules of 8-50mm in largest dimension.
Exclusion Criteria:
- Patients with known bleeding diathesis; Platelet count < 50,000.
- Current use of systemic anticoagulation or antiplatelet therapy without the ability to hold therapy for the recommended amount of time prior to an invasive procedure (aspirin monotherapy is acceptable).
- Inability or unwillingness to give informed consent.
- Pregnant or nursing females, or females of child-bearing potential who decline a pregnancy test prior to enrollment.
- Pulmonary hypertension, defined as a right ventricular systolic pressure > 50 mmHg.
- Individuals with current or recent systematic conditions, such as, acute kidney injury, or conditions that would mandate anticoagulation, such as a recent coronary stent.
- International Normalized Ratio (INR) < 1.5.
- Do Not Resuscitate (DNR) status; Do Not Intubate (DNI) status.
Sites / Locations
- Mayo Clinic Rochester
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Standard forceps biopsy then research cryoprobe biopsy
Research cryoprobe biopsy then standard forceps biopsy
Subjects scheduled for a biopsy of lung lesions using robotic bronchoscopy as part of their standard of care will have the lung lesion biopsied using forceps first followed by cryoprobe.
Subjects scheduled for a biopsy of lung lesions using robotic bronchoscopy as part of their standard of care will have the lung lesion biopsied using the cryoprobe first followed by forceps.