Effect of Collagen/Vitamin C in Jumper's Knee; a RCT (Jumpfood)
Patellar Tendinopathy
About this trial
This is an interventional treatment trial for Patellar Tendinopathy focused on measuring collagen, progressive tendon loading therapy, gelatin, RCT
Eligibility Criteria
Inclusion Criteria:
- Age 16 - 40 years old (the chosen age range will minimize chances of other conditions causing anterior knee pain such as osteoarthritis among patients above 40 years and osteochondrotic diseases like Sinding-Larsen-Johansson syndrome and Osgood-Schlatter disease among patients below the age of 16).
- History of focal knee pain in patellar tendon or its patellar or tibial insertion in association with training and/or competition.
- Current symptom duration of at least 12 weeks.
- Sports participation at least once a week for at least one year.
- Palpation tenderness to the corresponding painful area on the patellar tendon.
- Focal patellar tendon pain during patellar tendon loading pain provocation test (single leg decline squat and/or single leg jump squat)
- Victorian Institute of Sports Assessment (VISA-P) score < 80 out of 100 points.
- Willingness to take (non-vegetarian) nutritional supplements.
Exclusion Criteria:
- - Known presence of inflammatory joint diseases (e.g. spondylarthropathy, gout or rheumatoid arthritis) or familial hypercholesterolaemia.
- Contraindications for MRI (pregnancy, metallic implants, etc.)
- Daily use of drugs with a putative effect on the patellar tendon in the preceding year (e.g. fluoroquinolones and statins)
- Knee surgery without a full completion of the rehabilitation program in the history of the index knee
- Previous patellar tendon rupture of the index knee
- Local injection therapy with corticosteroids, other drugs, blood, platelet rich plasma or stem cells in the preceding 12 months
- Acute knee or patellar tendon injuries (other than PT)
- Inability to perform the PTLE program
- Participation in other concomitant treatment programs
- Signs or symptoms of other coexisting knee pathology on physical examination (such as joint effusion and joint line tenderness) or additional diagnostics (Chondral lesion of the patella or trochlea on MRI or prepatellar bursitis on US).
- Already using collagen supplementation
Sites / Locations
- Gelderse Vallei HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Supplement + progressive tendon loading therapy
Placebo + progressive tendon loading therapy
The intervention consists of a nutritional supplement with 10g hydrolysed collagen and 40 mg vitamin C, in comparison to a placebo supplement consisting of maltodextrin. All participants in both groups will receive education, load management advices and a criteria-based PTLE consisting of 4 stages within the limits of pain during 24-weeks. This (training) intervention has recently been proven to be superior to eccentric training. Participants will be randomly assigned to receive either the nutritional supplement collagen/vitamin C (intervention) or a placebo supplement.
The placebo consists of maltodextrin. In comparison the intervention consists of a nutritional supplement with 10g hydrolysed collagen and 40 mg vitamin C. All participants in both groups will receive education, load management advices and a criteria-based PTLE consisting of 4 stages within the limits of pain during 24-weeks. This (training) intervention has recently been proven to be superior to eccentric training. Participants will be randomly assigned to receive either the nutritional supplement collagen/vitamin C (intervention) or a placebo supplement.