Back to resultsStressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Primary Purpose
Acute Psychological Stress
Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Acute psychological stress
Sponsored by
About this trial
This is an interventional basic science trial for Acute Psychological Stress
Eligibility Criteria
Inclusion Criteria:
18-30 years old
Exclusion Criteria:
Chronic medical or neurological condition Pregnant Current illness or infection Any condition that would prohibit engaging in physical exercise Any metal implants in body Claustrophobia
Sites / Locations
- Baylor University
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Acute psychological stress
Arm Description
Participants will undergo an acute psychological stress task that has been shown to elicit neural, cardiovascular, and psychological (feelings of stressfulness) responses.
Outcomes
Primary Outcome Measures
Oxygen consumption
Heart rate (bpm) measured by electrocardiogram
Neural activity measured by fMRI
Additional heart rate
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT05413512
Brief Title
Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Official Title
Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Study Type
Interventional
2. Study Status
Record Verification Date
June 2022
Overall Recruitment Status
Completed
Study Start Date
March 2, 2020 (Actual)
Primary Completion Date
September 30, 2021 (Actual)
Study Completion Date
September 30, 2021 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Baylor University
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
The present study will examine the relationship between metabolically excessive cardiovascular and neural responses to acute psychological stress using a cross-sectional approach.
Detailed Description
All participants in this study will undergo an acute psychological stress paradigm, there will be no randomization or assignment since all participants will complete the same tasks. Sample size was calculated based off of recent papers examining multivariate pattern brain responses predicting cardiovascular responses to stress.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Acute Psychological Stress
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
170 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Acute psychological stress
Arm Type
Experimental
Arm Description
Participants will undergo an acute psychological stress task that has been shown to elicit neural, cardiovascular, and psychological (feelings of stressfulness) responses.
Intervention Type
Other
Intervention Name(s)
Acute psychological stress
Intervention Description
Participants will undergo an acute psychological stress task that has been shown to elicit neural, cardiovascular, and psychological (feelings of stressfulness) responses.
Primary Outcome Measure Information:
Title
Oxygen consumption
Time Frame
20 minutes
Title
Heart rate (bpm) measured by electrocardiogram
Time Frame
20 minutes
Title
Neural activity measured by fMRI
Time Frame
20 minutes
Title
Additional heart rate
Time Frame
20 minutes
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
30 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
18-30 years old
Exclusion Criteria:
Chronic medical or neurological condition Pregnant Current illness or infection Any condition that would prohibit engaging in physical exercise Any metal implants in body Claustrophobia
Facility Information:
Facility Name
Baylor University
City
Waco
State/Province
Texas
ZIP/Postal Code
76799
Country
United States
12. IPD Sharing Statement
Plan to Share IPD
No
IPD Sharing Plan Description
There is no plan to share IPD with other rsearchers.
Learn more about this trial
Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
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