Ascitic Fluid Calprotectin as an Accurate Diagnostic Marker for Spontaneous Bacterial Peritonitis
Spontaneous Bacterial Peritonitis
About this trial
This is an interventional diagnostic trial for Spontaneous Bacterial Peritonitis
Eligibility Criteria
Inclusion Criteria:
-
The patients were divided into two groups:
- Non-SBP group: it included 25 patients with cirrhotic ascites without clinical or laboratory evidence of SBP.
- SBP group: it included 25 patients with cirrhotic ascites with SBP. They were diagnosed by positive ascitic fluid bacterial culture, an increase in PMNLs count in ascites (>250 cells/mm3) and without any intra-abdominal source of infection.
Exclusion Criteria:
(1) Cirrhotic patients with and without SBP receiving antibiotics in last 1 week.
(2) Recent abdominal surgery (<3 months). (3) abdominal malignancy [hepatocellular carcinoma (HCC), colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, cholangiocarcinoma].
(4) Intra-abdominal infected lesions, such as abscess, appendicitis, cholecystitis, and pancreatitis.
(5) History of inflammatory bowel disease (Crohn's disease, ulcerative colitis).
(6) patients with heart failure (HF), hematological, and autoimmune disorders were excluded.
Sites / Locations
- Sohag University HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
case
control
people who have spontaneous bacterial peritonitis
people who donot have spontaneous bacterial peritonitis