Antibiotyping and Prevalence of Virulent Genotypes Among Helicobacter Pylori and Their Impact on Response to Therapy
H Pylori Infection
About this trial
This is an interventional treatment trial for H Pylori Infection focused on measuring H Pylori Infection
Eligibility Criteria
Inclusion Criteria:
- Any patient is above 18 years old with symptomatic H pylori infection patients diagnosed by positive H pylori Ag in stool (naïve treatment).
Exclusion Criteria:
- Patients who aren't eligible to endoscopy.
- Patients are under 18 years old
- Patient's refusal
- history of antibiotics or proton pump inhibitor use during last month.
Sites / Locations
- Nariman Zaghloul Bekhiet
Arms of the Study
Arm 1
Other
One group of naive H.Pylori infection will submitted for upper endoscopy.
Upper endoscopy will be done under complete septic condition and multiple gastric biopsies from corpus and antrum will be taken for : Histopathological examination. Culture and sensitivity of endoscopic biopsies. detection of vacuolating cytotoxin A (Vac A) and cytotoxin-associated gene A (Cag A) virulent Helicobacter Pylori genotypes by polymerase chain reaction amplification(PCR). Then start empirical antibiotics regimens.