Intermittent Hypoxic Training (IHT) Versus Hyperbaric Oxygen Therapy (HBOT) for Aerobic Performance
Healthy Active Athletes
About this trial
This is an interventional treatment trial for Healthy Active Athletes focused on measuring triathletes, cyclists, mitochondria, HBOT, HBO, IHT
Eligibility Criteria
Inclusion Criteria:
- Vo2max above 3500 ml or Vo2max/kg above 50 ml/kg
- Age 18-45
- Subjects are active aerobic athletes, training regularly more than 4 exercise sessions per week.
- Subject willing and able to read, understand and sign an informed consent
Exclusion Criteria:
- Inability to attend scheduled clinic visits and/or comply with the study protocol
- Active malignancy
- Active smokers
- Previous treatment of HBOT for any reason prior to study enrollment.
- Chest pathology incompatible with pressure changes
- Major orthopedic injury at the past 3 months
- Inner ear disease
- Lung pathology
- The inability to perform an awake brain MRI
- Claustrophobia
- Previous neurologic conditions (e.g., Epilepsy, Brain tumors or s/p neurosurgery etc.)
- Comorbidities and medications that rule out the subject
Sites / Locations
- The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center (Assaf Harofeh)Recruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Hyperbaric Oxygen Therapy - HBOT
Intermittent Hypoxic Training - IHT
The protocol comprises of 40 consecutive hyperbaric oxygen treatment (HBOT) sessions, 5 sessions per week within a two months' period. The HBOT group will train for 60 minutes after the HBOT sessions, 3 times per week, in a normobaric normoxic environment according to individualized training protocol
The protocol comprises of 24 consecutive Intermittent Hypoxic Training (IHT) sessions, 3 sessions per week within a two months' period. Subjects will train according to individualized training protocol.