Transcranial Magnetic Stimulation on Somtosensory Cortex Enhances Motor Learning in People With Stroke
Transcranial Magnetic Stimulation, Stroke, Motor Learning
About this trial
This is an interventional treatment trial for Transcranial Magnetic Stimulation focused on measuring Transcranial magnetic stimulation, Stroke, Motor learning, Somatosensory cortex, Motor function
Eligibility Criteria
Inclusion Criteria:
- Having suffered an ischaemic or haemorrhagic stroke with less than 6 months of evolution
- Presenting a score >21 points on the Mini-mental State Examination scale.
Exclusion Criteria:
- Severe impairment of upper limb motor function (<15 points on the Fugl-Meyer Assessment Upper Extremity scale)
- Any contraindications to rTMS, such as metal implants, history of epileptic seizures or taking medication that lowers the seizure threshold
- Previous history of neurological pathology.
Sites / Locations
- Neuron Chamberí
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
repetitive transcranial magnetic stimulation
Sham repetitive transcranial magnetic stimulation
Participants in the experimental group will receive one hour of rehabilitation therapy daily with 30 minutes of Task Oriented Training (TOT) and 30 minutes of Robotic-Assisted Therapy (RAT), 5 days per week, and repetitive Transcranial Magnetic Stimulation (rTMS) will be applied. This process will comprise 5 weekly sessions of excitatory stimulation over the primary somatosensory area of the participant's affected side. For this purpose, the motor area will be localised and a coil will be placed 2 cm posterior to it. An isolated pulse will be applied to the motor area to ensure that the coil is not placed over the motor area using 110% of the motor resting threshold. After this, 24 trains of 5 Hz at an intensity of 90% of the motor resting threshold will be applied for 10 seconds, with a rest between series of 5 seconds (a total of 1200 pulses).
The control group treatment will consist of a daily one-hour session of 30 minutes of task-oriented training (TOT) and 30 minutes of robotic-assisted therapy (RAT), for 5 days per week, to which the repetitive Transcranial Magnetic Stimulation (rTMS) placebo treatment will be added. To achieve the placebo, the localisation of the area to be stimulated will be carried out but the coil will be placed in a vertical position so the current wil not go through the skull and the patient will just feel the vibration, communicating to the participant that it is likely that during the stimulation process he/she will not feel anything.