Acute Effects of Spirulina on Postprandial Glycemic Responses and Arterial Blood Pressure
Potential Abnormality of Glucose Tolerance, Appetitive Behavior, Blood Pressure
About this trial
This is an interventional other trial for Potential Abnormality of Glucose Tolerance focused on measuring blood glucose responses, blood pressure, spirulina, subjective appetite, blood glucose concentrations
Eligibility Criteria
Inclusion Criteria:
- healthy
- non-smokers
- men and women
- body mass index between 18 and 24.9 kg/m2
- normal blood pressure (systolic blood pressure <120 mmHg and diastolic blood pressure <80 mmHg)
- normal fasting blood glucose concentrations (<100 mg/dL)
Exclusion Criteria:
- Medical conditions (e.g., cardiovascular diseases, diabetes mellitus, kidney or liver conditions, severe clinical depression, gastrointestinal disorders)
- Under medications known to affect glycemia (glucocorticoids, metformin, thiazide diuretics)
- Allergy to spirulina
- Pregnancy
- Lactation
- Competitive sports
- Alcohol abuse
- Drug dependency
Sites / Locations
- Agricultural University of Athens
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Experimental
Glucose as reference food
Glucose beverage containing 4 g spirulina
Glucose beverage containing 6 g spirulina
Glucose beverage containing 8 g spirulina
Thirteen healthy young adults, with BMI between 18 and 29.9 kg/m2 (male: 3, female:10) after 10-14h fast, consumed 50 g available carbohydrates from D-glucose, two times, in different weeks as reference food along with 300 mL water; and 50 g available carbohydrates from beverages containing 4, 6 and 8 g spirulina, tested once, in different visits, along with 300 mL water. There was a washout period of at least two days between visits. Fingertip capillary blood glucose samples were taken at 0, 15, 30, 45, 60, 90 and 120min postmeal. The first glucose sample was taken exactly 15min after the beginning of the consumption of the tested food.
Thirteen healthy young adults, with BMI between 18 and 29.9 kg/m2 (male: 3, female:10) after 10-14h fast, consumed 50 g available carbohydrates from D-glucose, two times, in different weeks as reference food along with 300 mL water; and 50 g available carbohydrates from beverages containing 4, 6 and 8 g spirulina, tested once, in different visits, along with 300 mL water. There was a washout period of at least two days between visits. Fingertip capillary blood glucose samples were taken at 0, 15, 30, 45, 60, 90 and 120min postmeal. The first glucose sample was taken exactly 15min after the beginning of the consumption of the tested food.
Thirteen healthy young adults, with BMI between 18 and 29.9 kg/m2 (male: 3, female:10) after 10-14h fast, consumed 50 g available carbohydrates from D-glucose, two times, in different weeks as reference food along with 300 mL water; and 50 g available carbohydrates from beverages containing 4, 6 and 8 g spirulina, tested once, in different visits, along with 300 mL water. There was a washout period of at least two days between visits. Fingertip capillary blood glucose samples were taken at 0, 15, 30, 45, 60, 90 and 120min postmeal. The first glucose sample was taken exactly 15min after the beginning of the consumption of the tested food.
Thirteen healthy young adults, with BMI between 18 and 29.9 kg/m2 (male: 3, female:10) after 10-14h fast, consumed 50 g available carbohydrates from D-glucose, two times, in different weeks as reference food along with 300 mL water; and 50 g available carbohydrates from beverages containing 4, 6 and 8 g spirulina, tested once, in different visits, along with 300 mL water. There was a washout period of at least two days between visits. Fingertip capillary blood glucose samples were taken at 0, 15, 30, 45, 60, 90 and 120min postmeal. The first glucose sample was taken exactly 15min after the beginning of the consumption of the tested food.