Budesonia + Intratracheal Surfactant in Incidence of Bronchopulmonary Dysplasia
Respiratory Tract Diseases
About this trial
This is an interventional prevention trial for Respiratory Tract Diseases focused on measuring Surfactant/Budesonide, Bronchopulmonary Dysplasia. Preterm
Eligibility Criteria
Inclusion Criteria:
- Preterm newborn with clinical and radiographic data of respiratory distress syndrome requiring administration of surfactant.
Newborn both sexes. Preterm newborn requiring invasive and/or non-invasive ventilatory support. Preterm infant who has and does not have antenatal exposure to steroids.
Exclusion Criteria:Patient with major congenital malformations, term newborn
• Elimination criteria: Patient whose parents withdraw their consent.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
intratracheal administration of surfactant/budesonide on the incidence of bronchopulmonary dysplasia
intratracheal administration of surfactant on the incidence of bronchopulmonary dysplasia
Group A will be given surfactant (beractant, lung phospholipids of bovine origin. Injectable suspension 1ml contains 25mg) at a dose of 100mg/kg or 4ml/kg and budesonide (budesonide, nebulized suspension 2ml contains 0.500mg) at a dose of 0.250 mg/kg or 1 ml/kg.
Group B will receive surfactant alone (beractant, lung phospholipids of bovine origin. Injectable suspension 1ml contains 25mg) administered at a dose of 100mg/kg or 4ml/kg.