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Effect of Remote Patient Monitoring and Patient Education on Patient Activation and Glycemic Control in Individuals With Type 2 Diabetes

Primary Purpose

Diabetes Mellitus, Type 2

Status
Withdrawn
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Remote Patient Monitoring
Sponsored by
Tracy Jalbuena MD
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Diabetes Mellitus, Type 2 focused on measuring remote patient monitoring, glycemic control

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Be enrolled in Living Well with Diabetes education program
  • Have an HbA1c% ≥ 8 in the prior 6 months
  • Be capable of providing consent
  • Be adults (age 18 or over)

Exclusion Criteria:

  • Primarily managed by endocrinology for their diabetes (> 1 visit with endocrinology in the previous 12 months)
  • Incarcerated
  • PCP not at one of the 30 primary care practices listed (see attachment List of PCP Practices)
  • Diagnosed with type 1 diabetes
  • Candidate for continuous glucose monitoring, as defined by Centers for Medicare and Medicaid Services as using at least three insulin injections per day, any combination of types of insulins
  • Pregnant
  • Have previously participated in the Living Well with Diabetes/Virtual Diabetes Self-Management Program
  • Have previously used a remote patient monitoring device for diabetes management
  • Have a diagnosis of dementia or other clinical diagnosis that would impair participation capacity
  • Currently participating in any other clinical trial regarding diabetes care or management
  • Currently enrolled in hospice
  • Currently residing in a long term care or rehabilitation facility

Sites / Locations

  • PenBay Medical Center

Arms of the Study

Arm 1

Arm 2

Arm Type

No Intervention

Experimental

Arm Label

Living Well with Diabetes

Living Well with Diabetes + Remote Patient Monitoring

Arm Description

Usual care is defined as participation in Living Well with Diabetes/Virtual Diabetes Self-Management Program, PCP evaluation and management, including medication adjustment or interventions, and other types of interventions depending on clinical judgement. This may include eConsults between the provider and a pharmacist, in-person visits between the provider and the patient, synchronous telemedicine visits between the provider and the patient, and synchronous telemedicine visits between the pharmacist and the patient.

Remote patient monitoring as the intervention is defined as a tablet and Bluetooth-enabled glucometer technology that collects point-of-care (POC) blood glucose data from a patient outside of a traditional clinical setting, and securely transmits this data to Epic for review and potential intervention.

Outcomes

Primary Outcome Measures

Mean HbA1c%
Average glycated hemoglobin
Mean HbA1c%
Average glycated hemoglobin
Mean change in HbA1c%
Average change in percentage of HbA1c from baseline to 6 months after enrollment
Mean change in HbA1c%
Average change in percentage of HbA1c from baseline to 9 months after enrollment
Percentage of participants in each group who have HbA1c < 7%
Percentage of participants in each group with HbA1c < 7%
Percentage of participants in each group who have HbA1c < 7%
Percentage of participants in each group with HbA1c < 7%

Secondary Outcome Measures

PAM-13 at 6 months after enrollment
PAM-13 Patient Activation Measure Survey Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes
PAM-13 at 9 months after enrollment
PAM-13 Patient Activation Measure Survey PAM-13 Patient Activation Measure Survey Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes
Mean change in PAM-13 at 6 months
Average change in PAM-13 Patient Activation Measure Survey score from baseline to 6 months after enrollment Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes
Mean change in PAM-13 at 9 months
Average change in PAM-13 Patient Activation Measure Survey score from baseline to 9 months after enrollment Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes

Full Information

First Posted
August 30, 2022
Last Updated
February 15, 2023
Sponsor
Tracy Jalbuena MD
Collaborators
MaineHealth, Health Resources and Services Administration (HRSA)
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1. Study Identification

Unique Protocol Identification Number
NCT05541120
Brief Title
Effect of Remote Patient Monitoring and Patient Education on Patient Activation and Glycemic Control in Individuals With Type 2 Diabetes
Official Title
Effect of Remote Patient Monitoring and Patient Education on Patient Activation and Glycemic Control in Individuals With Type 2 Diabetes
Study Type
Interventional

2. Study Status

Record Verification Date
February 2023
Overall Recruitment Status
Withdrawn
Why Stopped
Lack of participants eligible for study
Study Start Date
October 18, 2022 (Actual)
Primary Completion Date
June 30, 2026 (Anticipated)
Study Completion Date
August 31, 2026 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor-Investigator
Name of the Sponsor
Tracy Jalbuena MD
Collaborators
MaineHealth, Health Resources and Services Administration (HRSA)

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
This is a randomized controlled trial of the use of Remote Patient Monitoring (RPM) compared to usual care among rural patients with poorly controlled type 2 diabetes. Usual care is defined as participation in Living Well with Diabetes/Virtual Diabetes Self-Management Program and Primary Care Provider evaluation and management at the providers' discretion, including medication adjustment or interventions, and other types of interventions depending on clinical judgement.
Detailed Description
Effect of Remote Patient Monitoring and Patient Education on Patient Activation and Glycemic Control in Individuals with Type 2 Diabetes Summary ABSTRACT In 2021, the MaineHealth Telehealth team was awarded a five-year, $1.7 million "Evidence-Based Telehealth Network Program" grant (EB TNPG) from Health Resources and Services Administration (HRSA). This grant is aimed at improving patient access to educational and management services for patients with type 2 diabetes in the rural Maine primary care setting by implementing RPM. The RPM devices will be used to transmit a participant's home point-of-care blood glucose values directly into MaineHealth's electronic medical record in real time. While there is strong evidence for diabetes self-management programs such as Living Well with Diabetes, the importance of patient engagement in clinical outcomes, the validity of the Patient Activation Measure (PAM-13®) survey to measure patient activation, and the overall efficacy of remote patient monitoring, there have been no randomized controlled trials looking at patient activation in remote patient monitoring in this important patient group. The investigators aim to address this in this study by conducting a randomized controlled trial of the use of RPM among rural patients with poorly controlled type 2 diabetes. The control group will have usual primary care provider care, including patient self-management tools, while the intervention group will have usual care + RPM. The investigators hypothesize that participation in RPM will be associated with decreases in HbA1c, increases in patient activation as measured by PAM-13® survey, and that increases in patient activation will be associated with decreases in HbA1c. STUDY PROCESS The study will be conducted over 5 years, and participants will be enrolled on a continuous rolling basis, with 70 total RPM kits available at any one time from a 3rd party vendor, Health Recovery Solutions (HRS). The maximum total number of participants the study can accommodate is 700, with 350 participants in each arm. The study team hopes for total enrollment as close to 700 as possible, but understands that total enrollment may be significantly less than 700. Point-of-care blood glucose values from the RPM study arm will flow into MaineHealth's electronic medical record (Epic) in real time. Every other week, the values will be reviewed by a clinical pharmacist with expertise in diabetes management. If an intervention or adjustment in the patient's regimen is indicated, the pharmacist will reach out to the Primary Care Provider (PCP) team to make this recommendation. The RPM intervention for each participant will be 6 months, at which point HRS will collect the RPM electronic tablet, and the PAM-13® survey will be administered. At 9 months after enrollment, the third HbA1c value will be collected from the electronic medical record, and the third administration of PAM-13® will take place. The PAM-13® survey will be administered through one of two methods 1) REDCap electronic form, the link for which will be sent to the participant by email, or 2) by telephone, administered by the Study Coordinator. Recruitment of participants will continue through the early part of 2026. Data will be analyzed during spring and summer of 2026, and the grant's end date is August 31, 2026. This study has been approved by MaineHealth's IRB as of Aug 5, 2022.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Diabetes Mellitus, Type 2
Keywords
remote patient monitoring, glycemic control

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Model Description
This study is a randomized controlled trial of the use of RPM compared to usual care among MaineHealth's rural patients with poorly controlled diabetes, where the participant's diabetes is managed primarily by primary care (as opposed to endocrinology). Usual care is defined as participation in Living Well with Diabetes/Virtual Diabetes Self-Management Program, PCP evaluation and management at the providers' discretion, including medication adjustment or interventions, and other types of interventions depending on clinical judgement. This may include eConsults between the provider and a pharmacist, in-person visits between the provider and the patient, synchronous telemedicine visits between the provider and the patient, and synchronous telemedicine visits between the pharmacist and the patient.
Masking
None (Open Label)
Allocation
Randomized
Enrollment
0 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Living Well with Diabetes
Arm Type
No Intervention
Arm Description
Usual care is defined as participation in Living Well with Diabetes/Virtual Diabetes Self-Management Program, PCP evaluation and management, including medication adjustment or interventions, and other types of interventions depending on clinical judgement. This may include eConsults between the provider and a pharmacist, in-person visits between the provider and the patient, synchronous telemedicine visits between the provider and the patient, and synchronous telemedicine visits between the pharmacist and the patient.
Arm Title
Living Well with Diabetes + Remote Patient Monitoring
Arm Type
Experimental
Arm Description
Remote patient monitoring as the intervention is defined as a tablet and Bluetooth-enabled glucometer technology that collects point-of-care (POC) blood glucose data from a patient outside of a traditional clinical setting, and securely transmits this data to Epic for review and potential intervention.
Intervention Type
Device
Intervention Name(s)
Remote Patient Monitoring
Intervention Description
Remote patient monitoring as the intervention is defined as a tablet and Bluetooth-enabled glucometer technology that collects point-of-care (POC) blood glucose data from a patient outside of a traditional clinical setting, and securely transmits this data to Epic for review and potential intervention.
Primary Outcome Measure Information:
Title
Mean HbA1c%
Description
Average glycated hemoglobin
Time Frame
6 months after enrollment
Title
Mean HbA1c%
Description
Average glycated hemoglobin
Time Frame
9 months after enrollment
Title
Mean change in HbA1c%
Description
Average change in percentage of HbA1c from baseline to 6 months after enrollment
Time Frame
6 months after enrollment
Title
Mean change in HbA1c%
Description
Average change in percentage of HbA1c from baseline to 9 months after enrollment
Time Frame
9 months after enrollment
Title
Percentage of participants in each group who have HbA1c < 7%
Description
Percentage of participants in each group with HbA1c < 7%
Time Frame
6 months after enrollment
Title
Percentage of participants in each group who have HbA1c < 7%
Description
Percentage of participants in each group with HbA1c < 7%
Time Frame
9 months after enrollment
Secondary Outcome Measure Information:
Title
PAM-13 at 6 months after enrollment
Description
PAM-13 Patient Activation Measure Survey Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes
Time Frame
6 months after enrollment
Title
PAM-13 at 9 months after enrollment
Description
PAM-13 Patient Activation Measure Survey PAM-13 Patient Activation Measure Survey Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes
Time Frame
9 months after enrollment
Title
Mean change in PAM-13 at 6 months
Description
Average change in PAM-13 Patient Activation Measure Survey score from baseline to 6 months after enrollment Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes
Time Frame
6 months after enrollment
Title
Mean change in PAM-13 at 9 months
Description
Average change in PAM-13 Patient Activation Measure Survey score from baseline to 9 months after enrollment Unabbreviated scale title: Patient Activation Measure 13-Item Survey Minimum value: 0 Maximum value: 100 Higher values are associated with better health outcomes
Time Frame
9 months after enrollment

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Be enrolled in Living Well with Diabetes education program Have an HbA1c% ≥ 8 in the prior 6 months Be capable of providing consent Be adults (age 18 or over) Exclusion Criteria: Primarily managed by endocrinology for their diabetes (> 1 visit with endocrinology in the previous 12 months) Incarcerated PCP not at one of the 30 primary care practices listed (see attachment List of PCP Practices) Diagnosed with type 1 diabetes Candidate for continuous glucose monitoring, as defined by Centers for Medicare and Medicaid Services as using at least three insulin injections per day, any combination of types of insulins Pregnant Have previously participated in the Living Well with Diabetes/Virtual Diabetes Self-Management Program Have previously used a remote patient monitoring device for diabetes management Have a diagnosis of dementia or other clinical diagnosis that would impair participation capacity Currently participating in any other clinical trial regarding diabetes care or management Currently enrolled in hospice Currently residing in a long term care or rehabilitation facility
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Tracy Jalbuena, MD
Organizational Affiliation
MaineHealth
Official's Role
Principal Investigator
Facility Information:
Facility Name
PenBay Medical Center
City
Rockport
State/Province
Maine
ZIP/Postal Code
04856
Country
United States

12. IPD Sharing Statement

Plan to Share IPD
No
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Effect of Remote Patient Monitoring and Patient Education on Patient Activation and Glycemic Control in Individuals With Type 2 Diabetes

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