The Effect of Aerobic Exercise Training in Patients With Type III Spinal Muscular Atrophy
Neuromuscular Diseases, Spinal Muscular Atrophy Type 3
About this trial
This is an interventional treatment trial for Neuromuscular Diseases focused on measuring Spinal Muscular Atrophy Type 3, Aerobic Training, SMN protein level, Physiotherapy
Eligibility Criteria
Inclusion Criteria:
- Have been diagnosed of SMA Type 3 confirmed by genetic analysis,
- Between the ages of 10-50,
- Being able to walk 25 m without assistive device
Exclusion criteria:
- Using research drugs for SMA treatment other than Nusinersen treatment,
- Having a serious systemic disease that may prevent exercise,
- Have had a lower extremity injury and/or surgery in the last 6 months,
- To be applying a regular aerobic training program in the last 6 months
Sites / Locations
- Istanbul Faculty of Medicine, Department of Neurological SciencesRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Aerobic Exercise Training Group
Control Group
Aerobic training will be performed 3 days a week for 12 weeks at 60% -%75 of their maximum hearth rate with 30 minutes total duration consisting of 5 min warm up and 5 min cool down period in treatment group. Home exercise program will be given. This home program will include stretching, breathing, normal joint movement for 3 to 5 days a week
Home exercise program will be given. This home program will include stretching, breathing, normal joint movement, for 3 or 5 days a week.