Music as an Adjunctive Epileptic Seizure Treatment Option (MAESTRO)
Epilepsy, Neurocognitive Disorders
About this trial
This is an interventional treatment trial for Epilepsy
Eligibility Criteria
Inclusion Criteria:
- Children diagnosed with drug resistant epilepsy as per International League Against Epilepsy criteria: failure of adequate trials of two tolerated and appropriately chosen and used anti-seizure medication (ASM) schedules to achieve sustained seizure freedom.
Exclusion Criteria:
- Children who undergo changes in ASM treatment during the study period.
- Children with a seizure frequency of less than two episodes per month.
- Children who underwent changes in ASM therapy less than one month before the study period.
- Children included in other clinical intervention studies at the time of recruitment.
Sites / Locations
- Royal Aberdeen Children's HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Intervention arm
Control arm
Patients will be issued Mp3 players and speakers with music files in Mp3 formatted by the randomization team. The intervention arm will be issued the first movement (8 minutes, 22 seconds) of Mozart's Sonata for Two Pianos in D Major, K448. They will be exposed to it once a day during wakefulness for two consecutive months.
Patients will be issued Mp3 players and speakers with music files in Mp3 formatted by the randomization team. The control arm will receive the first movement (8 minutes, 34 seconds) of Mozart's Fantasia for Piano in C Minor, K 475. Although from the same composer, the control sonata has been found not to have neurostimulating properties. They will be exposed to it once a day during wakefulness for two consecutive months.