Pain Inflammation and Cannabis in HIV (PITCH-E)
HIV Infections, Neuropathic Pain, Cannabis
About this trial
This is an interventional treatment trial for HIV Infections
Eligibility Criteria
Inclusion Criteria:
- >= 18 years old
- Diagnosis of HIV
- Fluency in English
- Active certification for medical cannabis
- No medical cannabis dispensed or used within the previous 30 days
- Intends to purchase soft-gel capsule medical cannabis at Vireo
- ICD-10 (International Classification of Diseases 10th Revision) diagnosis code for neuropathic pain, OR
- Neuropathic pain in problem list of electronic medical record, OR
- Neuropathic pain questionnaire-short form>0
Exclusion Criteria:
- Inability to provide informed consent
- Inability to complete 14 weeks of study visits
- Medical cannabis use within 30 days prior to enrollment
- Unique pain symptoms (e.g. multiple sclerosis, rheumatoid arthritis)
- Terminal illness
- Current or prior psychotic disorder
- Street cannabis, opioid, cocaine, or benzodiazepine use in the past 30 days
- Dispensed opioids of benzodiazepines within 60 days
- Non-steroidal anti-inflammatory use within 7 days prior to enrollment
- Steroid use within the past 14 days with duration of therapy >=21 days
Sites / Locations
- Montefiore Health SystemRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Other
Other
Other
Other
Coupon for a Discounted Placebo Product
Coupon for a Discounted High THC Product
Coupon for a Discounted Equal THC and CBD Product
Coupon for a Discounted High CBD Product
We will observe participants who were previously randomized to a coupon for discounted placebo soft-gel capsules by our collaborators, Vireo.
We will observe participants who were previously randomized to a coupon for discounted 4.3 mg THC/0.7 mg CBD soft-gel capsules by our collaborators, Vireo.
We will observe participants who were previously randomized to a coupon for discounted 2.5 mg THC/2.5 mg CBD soft-gel capsules by our collaborators, Vireo.
We will observe participants who were previously randomized to a coupon for discounted 0.2 mg THC/4.8 mg CBD soft-gel capsules by our collaborators, Vireo.