Modeling Spinal Mobility in Ankylosing Spondylitis: Towards New Telekinetic Biomarkers (TELESPA)
Ankylosing Spondylitis
About this trial
This is an interventional diagnostic trial for Ankylosing Spondylitis focused on measuring rheumatology, Rehabilitation, Bioinformatics, Spondylitis, Motion sensor, XSENS-Awinda
Eligibility Criteria
Inclusion Criteria:
- Age 18-65
- BMI between 18.5 and 30
- Written informed consent
- Same gender and age within +/- 3 years compared to an unmatched AS patient
Inclusion criteria specific to the AS group:
- Age 18-65
- BMI between 18.5 and 30
- Written informed consent
AS meeting the ASAS (Assessment of Spondylo Arthritis International Society) criteria, i.e. with spinal pain ≥ 3 months old, with an age of diagnosis < 45 years, with:
- Sacroiliitis on imaging AND ≥ 1 sign of spondylarthritis. OR
- HLA-B27 (human leukocyte antigen-B27) positive AND ≥ 2 other signs of spondylarthritis
Exclusion Criteria:
- Traumatic, tumoral or infectious low back pain
- History of spinal fracture
- History of lumbar, pelvis, hips, ankles, and/or knees surgery
- Severe scoliosis defined by a Cobb angle > 50°
- Severe impairment of uncorrected visual acuity
- Concomitant pathology responsible for ataxia
- Lumbar arthrodesis of two or more stages
- Pregnant or breastfeeding women
- Patient unable to give consent: patient under guardianship or curators, mentally retarded, dementia, language barrier
- Patient not affiliated to a social security plan
- Patient under legal protection
Sites / Locations
- Centre Hospitalier Universitaire de MontpellierRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
AS patients
healthy volunteers
Evaluation of kinematic parameters by wearing X-Sens sensors in different movements (flexion and extension of the spine, tying shoelaces, picking up an object on the ground, walking, etc.)
Evaluation of kinematic parameters by wearing X-Sens sensors in different movements (flexion and extension of the spine, tying shoelaces, picking up an object on the ground, walking, etc.)