A Phase III of COVID-19 Vaccine EuCorVac-19 in Healthy Adults Aged 18 Years and Older
COVID-19
About this trial
This is an interventional prevention trial for COVID-19
Eligibility Criteria
Inclusion Criteria: Individuals aged 18 years and older who voluntarily decide to participate in this study and provide written informed consent Female of childbearing potential who agree to use medically allowed methods of contraception during the study period Individuals who agrees not to perform blood donation and transfusion during the study period Exclusion Criteria: Individual being considered to be confirmed COVID-19 Direct contact with COVID-19 infected person within 14 days prior to the 1st dose of the IP Individuals at high risk of exposure to SARS-CoV-2 Individuals with clinically significant abnormalities in clinical laboratory tests, ECGs, and chest X-ray during screening Individuals with fever within 72 hours prior to the 1st dose of the IP or suspected other infectious disease or symptoms associated with other infectious disease Individuals with serious medical or psychiatric disease History of SARS-CoV or MERS-CoV infection History of allergic reaction or hypersensitivity reactions to any of components of the IP History of serious adverse events, serious allergic reaction or serious hypersensitivity reactions to vaccination History of receiving organ or bone marrow transplant Suspected or history of drug abuse or alcohol abuse within 6 months prior to vaccination History of vaccination against SARS-CoV, MERS-CoV, or SARS-CoV-2 History of vaccination with test vaccine substance Treatment with immunosuppressants or immune modifying drugs History of treatment with antipsychotics or opioid dependence Pregnant or lactating women Other reasons based on which the individual is considered to be ineligible for this study in the opinion of the investigator
Sites / Locations
- Trial siteRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Active Comparator
Experimental
Active Comparator
Test group(EuCorVac-19) - Cohort A
Comparator group(ChAdOx1) - Cohort A
Test group(EuCorVac-19) - Cohort B
Comparator group(ChAdOx1) - Cohort B
Cohort A - Immunogenicity cohort
Cohort A - Immunogenicity cohort
Cohort B - Safety cohort
Cohort B - Safety cohort