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Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation (JANUS)

Primary Purpose

Locally Advanced Rectal Carcinoma, Stage II Rectal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8

Status

Recruiting

Phase

Phase 2

Locations

United States

Study Type

Interventional

Intervention

Capecitabine

5-fluorouracil

Leucovorin calcium

Irinotecan

Oxaliplatin

Long Course Chemoradiotherapy

Computed Tomography

Magnetic Resonance Imaging

Sigmoidoscopy

biopsy

About this trial

This is an interventional treatment trial for Locally Advanced Rectal Carcinoma

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Stage: Clinical stage II or III rectal adenocarcinoma defined as T4N0 or any T with node positive disease (any T, N+); also T3N0 requiring abdominal perineal resection (APR) or coloanal anastomosis Tumor site: Rectum; =< 12cm from the anal verge No prior systemic chemotherapy, targeted therapy, or immunotherapy; or radiation therapy administered as treatment for colorectal cancer within the past 5 years is allowed Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects * Therefore, for women of childbearing potential only, a negative pregnancy test (urine or serum according to institutional guidelines) done =< 14 days prior to registration is required. Female subjects agree to use highly effective contraception combined with an additional barrier method (e.g, diaphragm, with a spermicide) while on study and for >= 9 months after last dose of study drug, and the same criteria are applicable to male subjects if they have a partner of childbirth potential. Male subject agrees to use a condom and not donate sperm while in this study and for >= 6 months after the last treatment Age >= 18 years Eastern Cooperative Oncology Group (ECOG) performance status =< 2 (or Karnofsky >= 60%) Absolute neutrophil count (ANC) >= 1,500/mm^3 Platelet count >= 100,000/mm Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 50 mL/min ^3 Total bilirubin =< 1.5 x upper limit of normal (ULN) Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 3 x upper limit of normal (ULN) No upper rectal tumors (distal margin of tumor > 12 cm from the anal verge) No recurrent rectal cancer; prior transanal excision, prior distal sigmoid cancer with a low anastomosis No known mismatch repair deficient rectal adenocarcinoma Human immunodeficiency virus HIV-infected patients on effective anti-retro viral therapy with undetectable viral load within 6 months are eligible for this trial Patients with known history or current symptoms of cardiac disease, or history of treatment with cardio toxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification1. To be eligible for this trial, patients should be class 2B or better Chronic concomitant treatment with strong inhibitors of CYP3A4 is not allowed on this study. Patients on strong CYP3A4 inhibitors must discontinue the drug for 14 days prior to registration on the study * Chronic concomitant treatment with strong CYP3A4 inducers is not allowed. Patients must discontinue the drug 14 days prior to the start of study treatment

Sites / Locations

Mission Hope Medical Oncology - Arroyo Grande
City of Hope Comprehensive Cancer Center
Washington Hospital
City of Hope at Irvine Lennar
Los Angeles County-USC Medical Center
USC / Norris Comprehensive Cancer Center
Saint Joseph Hospital - Orange
UC Irvine Health/Chao Family Comprehensive Cancer Center
University of California Davis Comprehensive Cancer Center
Salinas Valley Memorial
Mission Hope Medical Oncology - Santa Maria
City of Hope South Pasadena
City of Hope South Bay
City of Hope Upland
Penrose-Saint Francis Healthcare
Saint Francis Cancer Center
Hartford Hospital
Midstate Medical Center
The Hospital of Central Connecticut
Beebe South Coastal Health Campus
Beebe Medical Center
Delaware Clinical and Laboratory Physicians PA
Helen F Graham Cancer Center
Medical Oncology Hematology Consultants PA
Christiana Care Health System-Christiana Hospital
Beebe Health Campus
MedStar Washington Hospital Center
Morton Plant Hospital
University of Florida Health Science Center - Gainesville
Saint Joseph's Hospital-North
AdventHealth Orlando
Saint Anthony's Hospital Cancer Care Center
Saint Joseph's Hospital/Children's Hospital-Tampa
Saint Luke's Cancer Institute - Boise
Saint Luke's Cancer Institute - Fruitland
Saint Luke's Cancer Institute - Meridian
Saint Luke's Cancer Institute - Nampa
Saint Luke's Cancer Institute - Twin Falls
Advocate Good Shepherd Hospital
Centralia Oncology Clinic
Northwestern University
John H Stroger Jr Hospital of Cook County
University of Chicago Comprehensive Cancer Center
Advocate Illinois Masonic Medical Center
AMG Crystal Lake - Oncology
Carle at The Riverfront
Cancer Care Specialists of Illinois - Decatur
Decatur Memorial Hospital
Northwestern Medicine Cancer Center Kishwaukee
Advocate Good Samaritan Hospital
Carle Physician Group-Effingham
Crossroads Cancer Center
Elmhurst Memorial Hospital
Northwestern Medicine Cancer Center Delnor
Advocate South Suburban Hospital
Northwestern Medicine Lake Forest Hospital
AMG Libertyville - Oncology
Condell Memorial Hospital
Carle Physician Group-Mattoon/Charleston
Edward Hospital/Cancer Center
UC Comprehensive Cancer Center at Silver Cross
Cancer Care Center of O'Fallon
Advocate Christ Medical Center
University of Chicago Medicine-Orland Park
Advocate Lutheran General Hospital
Southern Illinois University School of Medicine
Springfield Clinic
Memorial Medical Center
Carle Cancer Center
Northwestern Medicine Cancer Center Warrenville
Parkview Regional Medical Center
Mercy Hospital
Oncology Associates at Mercy Medical Center
Medical Oncology and Hematology Associates-West Des Moines
Mercy Cancer Center-West Lakes
Greater Regional Medical Center
Mercy Medical Center - Des Moines
Mission Cancer and Blood - Laurel
Mercy Medical Center-West Lakes
Ochsner Medical Center Jefferson
Lafayette Family Cancer Center-EMMC
Sinai Hospital of Baltimore
Boston Medical Center
Saint Joseph Mercy Hospital
Saint Joseph Mercy Brighton
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Saint Joseph Mercy Canton
Trinity Health IHA Medical Group Hematology Oncology - Canton
Caro Cancer Center
Saint Joseph Mercy Chelsea
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Beaumont Hospital - Dearborn
Beaumont Hospital - Farmington Hills
Genesys Hurley Cancer Institute
Hurley Medical Center
Sparrow Hospital
Trinity Health Saint Mary Mercy Livonia Hospital
Saint Mary's Oncology/Hematology Associates of Marlette
21st Century Oncology-Pontiac
Saint Joseph Mercy Oakland
William Beaumont Hospital-Royal Oak
Ascension Saint Mary's Hospital
Oncology Hematology Associates of Saginaw Valley PC
Ascension Saint Joseph Hospital
William Beaumont Hospital - Troy
Saint Mary's Oncology/Hematology Associates of West Branch
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Sanford Joe Lueken Cancer Center
Minnesota Oncology - Burnsville
Minnesota Oncology Hematology PA-Maplewood
Abbott-Northwestern Hospital
United Hospital
Minnesota Oncology Hematology PA-Woodbury
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Baptist Cancer Center-Grenada
Baptist Memorial Hospital and Cancer Center-Union County
Baptist Memorial Hospital and Cancer Center-Oxford
Baptist Memorial Hospital and Cancer Center-Desoto
Saint Francis Medical Center
Delbert Day Cancer Institute at PCRMC
Mercy Clinic-Rolla-Cancer and Hematology
Mercy Hospital Saint Louis
CoxHealth South Hospital
OptumCare Cancer Care at Seven Hills
OptumCare Cancer Care at Charleston
Radiation Oncology Centers of Nevada Central
Radiation Oncology Centers of Nevada Southeast
OptumCare Cancer Care at MountainView
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Comprehensive Cancer Centers of Nevada
OptumCare Cancer Care at Fort Apache
Renown Regional Medical Center
New Hampshire Oncology Hematology PA-Concord
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
The Dana-Farber Cancer Institute at Londonderry
Solinsky Center for Cancer Care
Memorial Sloan Kettering Basking Ridge
Memorial Sloan Kettering Monmouth
Memorial Sloan Kettering Bergen
Holy Name Hospital
Montefiore Medical Center-Einstein Campus
Montefiore Medical Center-Weiler Hospital
Montefiore Medical Center - Moses Campus
Roswell Park Cancer Institute
Memorial Sloan Kettering Commack
Northwell Health Cancer Institute at Huntington
Memorial Sloan Kettering Westchester
Northwell Health/Center for Advanced Medicine
NYU Winthrop Hospital
Laura and Isaac Perlmutter Cancer Center at NYU Langone
Mount Sinai West
Lenox Hill Hospital
Mount Sinai Hospital
Memorial Sloan Kettering Cancer Center
University of Rochester
Memorial Sloan Kettering Nassau
Wilmot Cancer Institute at Webster
Duke Cancer Institute Cary
UNC Lineberger Comprehensive Cancer Center
Wake Forest University at Clemmons
Duke University Medical Center
East Carolina University
Duke Raleigh Hospital
Wake Forest Baptist Health - Wilkes Medical Center
Wake Forest University Health Sciences
Sanford Bismarck Medical Center
Sanford Broadway Medical Center
Sanford Roger Maris Cancer Center
MetroHealth Medical Center
Ohio State University Comprehensive Cancer Center
University of Oklahoma Health Sciences Center
Mercy Hospital Oklahoma City
Clackamas Radiation Oncology Center
Providence Cancer Institute Clackamas Clinic
Providence Newberg Medical Center
Providence Willamette Falls Medical Center
Providence Portland Medical Center
Providence Saint Vincent Medical Center
Lehigh Valley Hospital-Cedar Crest
UPMC Altoona
UPMC Camp Hill
Carlisle Regional Cancer Center
Christiana Care Health System-Concord Health Center
UPMC Hillman Cancer Center Erie
Saint Vincent Hospital
UPMC Cancer Center at UPMC Horizon
UPMC Cancer Centers - Arnold Palmer Pavilion
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Penn State Milton S Hershey Medical Center
IRMC Cancer Center
Jefferson Hospital
UPMC-Johnstown/John P. Murtha Regional Cancer Center
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Forbes Hospital
UPMC Hillman Cancer Center - Part of Frick Hospital
Arnold Palmer Cancer Center Medical Oncology Norwin
UPMC Hillman Cancer Center - New Castle
Thomas Jefferson University Hospital
Allegheny General Hospital
UPMC-Saint Margaret
University of Pittsburgh Cancer Institute (UPCI)
UPMC-Shadyside Hospital
UPMC-Passavant Hospital
UPMC-Saint Clair Hospital Cancer Center
UPMC Cancer Center at UPMC Northwest
UPMC Cancer Center-Washington
UPMC Washington Hospital Radiation Oncology
Chester County Hospital
Wexford Health and Wellness Pavilion
Divine Providence Hospital
Asplundh Cancer Pavilion
UPMC Memorial
Medical University of South Carolina
Gibbs Cancer Center-Gaffney
Tidelands Georgetown Memorial Hospital
Prisma Health Cancer Institute - Faris
Prisma Health Cancer Institute - Eastside
Prisma Health Cancer Institute - Greer
Gibbs Cancer Center-Pelham
MUSC Health Tidelands Health Radiation Therapy Center
Prisma Health Cancer Institute - Seneca
Spartanburg Medical Center
MGC Hematology Oncology-Union
Lexington Medical Center
Sanford Cancer Center Oncology Clinic
Avera Cancer Institute
Sanford USD Medical Center - Sioux Falls
Avera Cancer Institute at Yankton
Baptist Memorial Hospital and Cancer Center-Collierville
The West Clinic - Wolf River
Baptist Memorial Hospital and Cancer Center-Memphis
Vanderbilt Breast Center at One Hundred Oaks
Vanderbilt University/Ingram Cancer Center
The Don and Sybil Harrington Cancer Center
Lyndon Baines Johnson General Hospital
M D Anderson Cancer Center
University of Texas Health Science Center at San Antonio
Farmington Health Center
University of Utah Sugarhouse Health Center
Huntsman Cancer Institute/University of Utah
Inova Schar Cancer InstituteRecruiting
Inova Fair Oaks HospitalRecruiting
Inova Fairfax HospitalRecruiting
Inova Loudoun HospitalRecruiting
Virginia Cancer Institute
VCU Massey Cancer Center at Stony Point
Virginia Commonwealth University/Massey Cancer Center
Valley Medical Center
Virginia Mason Medical CenterRecruiting
FHCC South Lake Union
Fred Hutchinson Cancer Research Center
University of Washington Medical Center - Montlake
Langlade Hospital and Cancer Center
Aurora Cancer Care-Southern Lakes VLCC
Marshfield Medical Center-EC Cancer Center
Aurora Health Care Germantown Health Center
Aurora Cancer Care-Grafton
Saint Vincent Hospital Cancer Center Green Bay
Saint Vincent Hospital Cancer Center at Saint Mary's
Aurora BayCare Medical Center
Aurora Cancer Care-Kenosha South
Aurora Bay Area Medical Group-Marinette
Marshfield Medical Center-Marshfield
Froedtert Menomonee Falls Hospital
Aurora Cancer Care-Milwaukee
Aurora Saint Luke's Medical Center
Medical College of Wisconsin
Aurora Sinai Medical Center
Marshfield Clinic-Minocqua Center
Drexel Town Square Health Center
Vince Lombardi Cancer Clinic - Oshkosh
Aurora Cancer Care-Racine
Marshfield Medical Center-Rice Lake
Saint Vincent Hospital Cancer Center at Sheboygan
Vince Lombardi Cancer Clinic-Sheboygan
Ascension Saint Michael's Hospital
Marshfield Medical Center-River Region at Stevens Point
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Aurora Medical Center in Summit
Vince Lombardi Cancer Clinic-Two Rivers
Aspirus Regional Cancer Center
Aurora Cancer Care-Milwaukee West
Aurora West Allis Medical Center
Froedtert West Bend Hospital/Kraemer Cancer Center
Marshfield Medical Center - Weston
Aspirus Cancer Care - Wisconsin Rapids

Arms of the Study

Arm 1

Arm 2

Arm Type

Active Comparator

Experimental

Arm Label

Group I (LCRT, FOLFOX or CAPOX)

Group II (LCRT, FOLFIRINOX)

Arm Description

Patients receive long-course chemoradiation therapy on study and then receive either: FOLFOX regimen consisting of leucovorin IV, fluorouracil IV, and oxaliplatin IV or CAPOX consisting of capecitabine PO, and oxaliplatin IV on study. Patients undergo CT scan, MRI, and biospecimen collection throughout the trial. Patients also undergo sigmoidoscopy throughout the trial and biopsy during screening.

Patients receive long-course chemoradiation therapy on study and then receive FOLFIRINOX regimen consisting of leucovorin IV, fluorouracil IV, irinotecan IV, and oxaliplatin IV on study. Patients undergo CT scan, MRI scan, and blood specimen collection throughout the trial. Patients undergo sigmoidoscopy throughout the trial and biopsy during screening.

Outcomes

Primary Outcome Measures

Clincal Complete Response (cCR) Rates

efined as the number of patients who achieved cCR at the end of total neoadjuvant therapy (TNT) divided by number of patients included in the analysis population. This endpoint will be assessed within 8-12 weeks after completion of TNT. If there is a cCR, then the patient will be counted in the numerator. If there is a near-complete response (nCR) then a re-evaluation within 4-8 weeks will be performed. If the tumor has evolved to a cCR, then the patient will be counted in the numerator. Otherwise, the patient will be deemed as NOT achieving cCR status. divided by number of patients included in the analysis population.

Secondary Outcome Measures

Disease-free survival (DFS) rate

Defined as the time from date of randomization to the date of first occurrence of the following events: death due to all causes, tumor that recurs locally after an R0 total mesorectal excision (TME), tumor that regrows after an initial apparent clinical and radiological CR and cannot be surgically removed with an R0 TME, and M1 disease diagnosed at any point after the initiation of treatment.

Organ-preservation-time (OPT)

Defined as time from the date of randomization to the date of the first occurrence of the following events: TME performed or attempted, tumor that regrows after an initial apparent clinical and radiological complete response (CR), and death due to all causes.

Time to distant metastasis (TDM)

Will be estimated, in each arm, using the method of Kaplan-Meier and compared by a stratified Cox regression model.

Overall survival (OS)

Will be estimated, in each arm, using the method of Kaplan-Meier and compared by a stratified Cox regression model.

Incidence of adverse events (AEs)

Defined as the proportion of patients experienced at least one Grade 3, Grade 4, or Grade 5 of each type of AE. The overall adverse event rates for grade 3 or higher adverse events will be compared between two treatment groups using Chi-square test (or Fisher's exact test if the data in the contingency table is sparse).

Full Information

NCT ID

NCT05610163

First Posted

November 1, 2022

Last Updated

August 30, 2023

Sponsor

Alliance for Clinical Trials in Oncology

Collaborators

National Cancer Institute (NCI)

1. Study Identification

Unique Protocol Identification Number

NCT05610163

Brief Title

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

Acronym

JANUS

Official Title

The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing The Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients With Locally Advanced Rectal Cancer

Study Type

Interventional

2. Study Status

Record Verification Date

August 2023

Overall Recruitment Status

Recruiting

Study Start Date

December 8, 2022 (Actual)

Primary Completion Date

September 2024 (Anticipated)

Study Completion Date

September 2032 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Alliance for Clinical Trials in Oncology

Collaborators

National Cancer Institute (NCI)

4. Oversight

Studies a U.S. FDA-regulated Drug Product

Studies a U.S. FDA-regulated Device Product

Data Monitoring Committee

Yes

5. Study Description

Brief Summary

This phase II trial compares the effect of irinotecan versus oxaliplatin after long-course chemoradiation in patients with stage II-III rectal cancer. Combination chemotherapy drugs, such as FOLFIRINOX (fluorouracil, irinotecan, leucovorin, and oxaliplatin), FOLFOX (leucovorin, fluorouracil, oxaliplatin, and irinotecan ), and CAPOX (capecitabin and oxaliplatin) work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. FOLFOX or CAPOX are used after chemoradiation as usual treatment for rectal cancer. Giving FOLFIRINOX after chemoradiation may increase the response rate and lead to higher rates of clinical complete response (with a chance of avoiding surgery) compared to FOLFOX or CAPOX after chemoradiation in patients with locally advanced rectal cancer.

Detailed Description

PRIMARY OBJECTIVE: I. To evaluate and compare the clinical complete response (cCR) rates in patients with locally advanced rectal cancer treated with neoadjuvant long-course neoadjuvant radiotherapy (LCRT) followed by neoadjuvant modified fluorouracil, irinotecan, leucovorin, and oxaliplatin (mFOLFIRINOX) versus neoadjuvant LCRT followed by neoadjuvant modified leucovorin , fluorouracil, and oxaliplatin (mFOLFOX6). SECONDARY OBJECTIVES: I. To evaluate and compare organ-preservation-time (OPT) between two treatment arms. II. To evaluate and compare the disease-free survival (DFS) time between the two treatment arms. III. To evaluate and compare time to distant metastasis between two treatment arms. IV. To evaluate and compare overall survival (OS) between two treatment arms. V. To evaluate and compare toxicity profiles of total neoadjuvant therapy (TNT) between two treatment arms. EXPLORATORY OBJECTIVE: I. Evaluation of circulating tumor deoxyribonucleic acid (ctDNA) kinetics during neoadjuvant therapy & surveillance and to correlate with radiographic, pathologic, and clinical outcomes. OUTLINE: Patients are randomized to 1 of 2 arms. GROUP I: Patients receive long-course chemoradiation therapy on study and then receive either: FOLFOX regimen consisting of leucovorin intravenously (IV), fluorouracil IV, and oxaliplatin IV or CAPOX consisting of capecitabine orally (PO), and oxaliplatin IV on study. Patients undergo computed tomography (CT) scan, magnetic resonance imaging (MRI), and biospecimen collection throughout the trial. Patients also undergo sigmoidoscopy throughout the trial and biopsy during screening. GROUP II: Patients receive long-course chemoradiation therapy on study and then receive FOLFIRINOX regimen consisting of leucovorin IV, fluorouracil IV, irinotecan IV, and oxaliplatin IV on study. Patients undergo CT scan, MRI scan, and blood specimen collection throughout the trial. Patients undergo sigmoidoscopy throughout the trial and biopsy during screening.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Locally Advanced Rectal Carcinoma, Stage II Rectal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8

7. Study Design

Primary Purpose

Treatment

Study Phase

Phase 2

Interventional Study Model

Sequential Assignment

Masking

None (Open Label)

Allocation

Randomized

Enrollment

312 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title

Group I (LCRT, FOLFOX or CAPOX)

Arm Type

Active Comparator

Arm Description

Arm Title

Group II (LCRT, FOLFIRINOX)

Arm Type

Experimental

Arm Description

Intervention Type

Drug

Intervention Name(s)

Capecitabine

Intervention Description

Given PO

Intervention Type

Drug

Intervention Name(s)

5-fluorouracil

Intervention Description

Given IV

Intervention Type

Drug

Intervention Name(s)

Leucovorin calcium

Intervention Description

Given IV

Intervention Type

Drug

Intervention Name(s)

Irinotecan

Intervention Description

Given IV

Intervention Type

Drug

Intervention Name(s)

Oxaliplatin

Intervention Description

Given IV

Intervention Type

Radiation

Intervention Name(s)

Long Course Chemoradiotherapy

Intervention Description

Receive LCRT

Intervention Type

Procedure

Intervention Name(s)

Computed Tomography

Intervention Description

undergo CT

Intervention Type

Procedure

Intervention Name(s)

Magnetic Resonance Imaging

Intervention Description

undergo MRI

Intervention Type

Procedure

Intervention Name(s)

Sigmoidoscopy

Intervention Description

undergo sigmoidoscopy

Intervention Type

Procedure

Intervention Name(s)

biopsy

Intervention Description

undergo biopsy

Primary Outcome Measure Information:

Title

Clincal Complete Response (cCR) Rates

Description

Time Frame

Up to 5 years

Secondary Outcome Measure Information:

Title

Disease-free survival (DFS) rate

Description

Time Frame

rom date of randomization, assessed up to 5 years

Title

Organ-preservation-time (OPT)

Description

Time Frame

From date of randomization, assessed up to 5 years

Title

Time to distant metastasis (TDM)

Description

Will be estimated, in each arm, using the method of Kaplan-Meier and compared by a stratified Cox regression model.

Time Frame

From the date of randomization to the date of first documented distant metastasis, assessed up to 5 years

Title

Overall survival (OS)

Description

Will be estimated, in each arm, using the method of Kaplan-Meier and compared by a stratified Cox regression model.

Time Frame

From the date of randomization to the date of death due to all causes, assessed up to 5 years

Title

Incidence of adverse events (AEs)

Description

Time Frame

Up to 5 years

10. Eligibility

Sex

All

Minimum Age & Unit of Time

18 Years

Accepts Healthy Volunteers

Eligibility Criteria

Central Contact Person:

First Name & Middle Initial & Last Name or Official Title & Degree

J. Joshua Smith, MD

Phone

212-639-5807

smithj5@mskcc.org

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

J. Joshua Smith, MD

Organizational Affiliation

Memorial Sloan Kettering Cancer Center

Official's Role

Study Chair

Facility Information:

Facility Name

Mission Hope Medical Oncology - Arroyo Grande

City

Arroyo Grande

State/Province

California

ZIP/Postal Code

93420

Country

United States

Individual Site Status

Suspended

Facility Name

City of Hope Comprehensive Cancer Center

City

Duarte

State/Province

California

ZIP/Postal Code

91010

Country

United States

Individual Site Status

Suspended

Facility Name

Washington Hospital

City

Fremont

State/Province

California

ZIP/Postal Code

94538

Country

United States

Individual Site Status

Suspended

Facility Name

City of Hope at Irvine Lennar

City

Irvine

State/Province

California

ZIP/Postal Code

92618

Country

United States

Individual Site Status

Suspended

Facility Name

Los Angeles County-USC Medical Center

City

Los Angeles

State/Province

California

ZIP/Postal Code

90033

Country

United States

Individual Site Status

Suspended

Facility Name

USC / Norris Comprehensive Cancer Center

City

Los Angeles

State/Province

California

ZIP/Postal Code

90033

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph Hospital - Orange

City

Orange

State/Province

California

ZIP/Postal Code

92868

Country

United States

Individual Site Status

Suspended

Facility Name

UC Irvine Health/Chao Family Comprehensive Cancer Center

City

Orange

State/Province

California

ZIP/Postal Code

92868

Country

United States

Individual Site Status

Suspended

Facility Name

University of California Davis Comprehensive Cancer Center

City

Sacramento

State/Province

California

ZIP/Postal Code

95817

Country

United States

Individual Site Status

Suspended

Facility Name

Salinas Valley Memorial

City

Salinas

State/Province

California

ZIP/Postal Code

93901

Country

United States

Individual Site Status

Suspended

Facility Name

Mission Hope Medical Oncology - Santa Maria

City

Santa Maria

State/Province

California

ZIP/Postal Code

93444

Country

United States

Individual Site Status

Suspended

Facility Name

City of Hope South Pasadena

City

South Pasadena

State/Province

California

ZIP/Postal Code

91030

Country

United States

Individual Site Status

Suspended

Facility Name

City of Hope South Bay

City

Torrance

State/Province

California

ZIP/Postal Code

90503

Country

United States

Individual Site Status

Suspended

Facility Name

City of Hope Upland

City

Upland

State/Province

California

ZIP/Postal Code

91786

Country

United States

Individual Site Status

Suspended

Facility Name

Penrose-Saint Francis Healthcare

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80907

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Francis Cancer Center

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80923

Country

United States

Individual Site Status

Suspended

Facility Name

Hartford Hospital

City

Hartford

State/Province

Connecticut

ZIP/Postal Code

06102

Country

United States

Individual Site Status

Suspended

Facility Name

Midstate Medical Center

City

Meriden

State/Province

Connecticut

ZIP/Postal Code

06451

Country

United States

Individual Site Status

Suspended

Facility Name

The Hospital of Central Connecticut

City

New Britain

State/Province

Connecticut

ZIP/Postal Code

06050

Country

United States

Individual Site Status

Suspended

Facility Name

Beebe South Coastal Health Campus

City

Frankford

State/Province

Delaware

ZIP/Postal Code

19945

Country

United States

Individual Site Status

Suspended

Facility Name

Beebe Medical Center

City

Lewes

State/Province

Delaware

ZIP/Postal Code

19958

Country

United States

Individual Site Status

Suspended

Facility Name

Delaware Clinical and Laboratory Physicians PA

City

Newark

State/Province

Delaware

ZIP/Postal Code

19713

Country

United States

Individual Site Status

Suspended

Facility Name

Helen F Graham Cancer Center

City

Newark

State/Province

Delaware

ZIP/Postal Code

19713

Country

United States

Individual Site Status

Suspended

Facility Name

Medical Oncology Hematology Consultants PA

City

Newark

State/Province

Delaware

ZIP/Postal Code

19713

Country

United States

Individual Site Status

Suspended

Facility Name

Christiana Care Health System-Christiana Hospital

City

Newark

State/Province

Delaware

ZIP/Postal Code

19718

Country

United States

Individual Site Status

Suspended

Facility Name

Beebe Health Campus

City

Rehoboth Beach

State/Province

Delaware

ZIP/Postal Code

19971

Country

United States

Individual Site Status

Suspended

Facility Name

MedStar Washington Hospital Center

City

Washington

State/Province

District of Columbia

ZIP/Postal Code

20010

Country

United States

Individual Site Status

Suspended

Facility Name

Morton Plant Hospital

City

Clearwater

State/Province

Florida

ZIP/Postal Code

33756

Country

United States

Individual Site Status

Suspended

Facility Name

University of Florida Health Science Center - Gainesville

City

Gainesville

State/Province

Florida

ZIP/Postal Code

32610

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph's Hospital-North

City

Lutz

State/Province

Florida

ZIP/Postal Code

33558

Country

United States

Individual Site Status

Suspended

Facility Name

AdventHealth Orlando

City

Orlando

State/Province

Florida

ZIP/Postal Code

32803

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Anthony's Hospital Cancer Care Center

City

Saint Petersburg

State/Province

Florida

ZIP/Postal Code

33705

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph's Hospital/Children's Hospital-Tampa

City

Tampa

State/Province

Florida

ZIP/Postal Code

33607

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Luke's Cancer Institute - Boise

City

Boise

State/Province

Idaho

ZIP/Postal Code

83712

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Luke's Cancer Institute - Fruitland

City

Fruitland

State/Province

Idaho

ZIP/Postal Code

83619

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Luke's Cancer Institute - Meridian

City

Meridian

State/Province

Idaho

ZIP/Postal Code

83642

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Luke's Cancer Institute - Nampa

City

Nampa

State/Province

Idaho

ZIP/Postal Code

83686

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Luke's Cancer Institute - Twin Falls

City

Twin Falls

State/Province

Idaho

ZIP/Postal Code

83301

Country

United States

Individual Site Status

Suspended

Facility Name

Advocate Good Shepherd Hospital

City

Barrington

State/Province

Illinois

ZIP/Postal Code

60010

Country

United States

Individual Site Status

Suspended

Facility Name

Centralia Oncology Clinic

City

Centralia

State/Province

Illinois

ZIP/Postal Code

62801

Country

United States

Individual Site Status

Suspended

Facility Name

Northwestern University

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60611

Country

United States

Individual Site Status

Suspended

Facility Name

John H Stroger Jr Hospital of Cook County

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60612

Country

United States

Individual Site Status

Suspended

Facility Name

University of Chicago Comprehensive Cancer Center

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60637

Country

United States

Individual Site Status

Suspended

Facility Name

Advocate Illinois Masonic Medical Center

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60657

Country

United States

Individual Site Status

Suspended

Facility Name

AMG Crystal Lake - Oncology

City

Crystal Lake

State/Province

Illinois

ZIP/Postal Code

60014

Country

United States

Individual Site Status

Suspended

Facility Name

Carle at The Riverfront

City

Danville

State/Province

Illinois

ZIP/Postal Code

61832

Country

United States

Individual Site Status

Suspended

Facility Name

Cancer Care Specialists of Illinois - Decatur

City

Decatur

State/Province

Illinois

ZIP/Postal Code

62526

Country

United States

Individual Site Status

Suspended

Facility Name

Decatur Memorial Hospital

City

Decatur

State/Province

Illinois

ZIP/Postal Code

62526

Country

United States

Individual Site Status

Suspended

Facility Name

Northwestern Medicine Cancer Center Kishwaukee

City

DeKalb

State/Province

Illinois

ZIP/Postal Code

60115

Country

United States

Individual Site Status

Suspended

Facility Name

Advocate Good Samaritan Hospital

City

Downers Grove

State/Province

Illinois

ZIP/Postal Code

60515

Country

United States

Individual Site Status

Suspended

Facility Name

Carle Physician Group-Effingham

City

Effingham

State/Province

Illinois

ZIP/Postal Code

62401

Country

United States

Individual Site Status

Suspended

Facility Name

Crossroads Cancer Center

City

Effingham

State/Province

Illinois

ZIP/Postal Code

62401

Country

United States

Individual Site Status

Suspended

Facility Name

Elmhurst Memorial Hospital

City

Elmhurst

State/Province

Illinois

ZIP/Postal Code

60126

Country

United States

Individual Site Status

Suspended

Facility Name

Northwestern Medicine Cancer Center Delnor

City

Geneva

State/Province

Illinois

ZIP/Postal Code

60134

Country

United States

Individual Site Status

Suspended

Facility Name

Advocate South Suburban Hospital

City

Hazel Crest

State/Province

Illinois

ZIP/Postal Code

60429

Country

United States

Individual Site Status

Suspended

Facility Name

Northwestern Medicine Lake Forest Hospital

City

Lake Forest

State/Province

Illinois

ZIP/Postal Code

60045

Country

United States

Individual Site Status

Suspended

Facility Name

AMG Libertyville - Oncology

City

Libertyville

State/Province

Illinois

ZIP/Postal Code

60048

Country

United States

Individual Site Status

Suspended

Facility Name

Condell Memorial Hospital

City

Libertyville

State/Province

Illinois

ZIP/Postal Code

60048

Country

United States

Individual Site Status

Suspended

Facility Name

Carle Physician Group-Mattoon/Charleston

City

Mattoon

State/Province

Illinois

ZIP/Postal Code

61938

Country

United States

Individual Site Status

Suspended

Facility Name

Edward Hospital/Cancer Center

City

Naperville

State/Province

Illinois

ZIP/Postal Code

60540

Country

United States

Individual Site Status

Suspended

Facility Name

UC Comprehensive Cancer Center at Silver Cross

City

New Lenox

State/Province

Illinois

ZIP/Postal Code

60451

Country

United States

Individual Site Status

Suspended

Facility Name

Cancer Care Center of O'Fallon

City

O'Fallon

State/Province

Illinois

ZIP/Postal Code

62269

Country

United States

Individual Site Status

Suspended

Facility Name

Advocate Christ Medical Center

City

Oak Lawn

State/Province

Illinois

ZIP/Postal Code

60453-2699

Country

United States

Individual Site Status

Suspended

Facility Name

University of Chicago Medicine-Orland Park

City

Orland Park

State/Province

Illinois

ZIP/Postal Code

60462

Country

United States

Individual Site Status

Suspended

Facility Name

Advocate Lutheran General Hospital

City

Park Ridge

State/Province

Illinois

ZIP/Postal Code

60068

Country

United States

Individual Site Status

Suspended

Facility Name

Southern Illinois University School of Medicine

City

Springfield

State/Province

Illinois

ZIP/Postal Code

62702

Country

United States

Individual Site Status

Suspended

Facility Name

Springfield Clinic

City

Springfield

State/Province

Illinois

ZIP/Postal Code

62702

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Medical Center

City

Springfield

State/Province

Illinois

ZIP/Postal Code

62781

Country

United States

Individual Site Status

Suspended

Facility Name

Carle Cancer Center

City

Urbana

State/Province

Illinois

ZIP/Postal Code

61801

Country

United States

Individual Site Status

Suspended

Facility Name

Northwestern Medicine Cancer Center Warrenville

City

Warrenville

State/Province

Illinois

ZIP/Postal Code

60555

Country

United States

Individual Site Status

Suspended

Facility Name

Parkview Regional Medical Center

City

Fort Wayne

State/Province

Indiana

ZIP/Postal Code

46845

Country

United States

Individual Site Status

Suspended

Facility Name

Mercy Hospital

City

Cedar Rapids

State/Province

Iowa

ZIP/Postal Code

52403

Country

United States

Individual Site Status

Suspended

Facility Name

Oncology Associates at Mercy Medical Center

City

Cedar Rapids

State/Province

Iowa

ZIP/Postal Code

52403

Country

United States

Individual Site Status

Suspended

Facility Name

Medical Oncology and Hematology Associates-West Des Moines

City

Clive

State/Province

Iowa

ZIP/Postal Code

50325

Country

United States

Individual Site Status

Suspended

Facility Name

Mercy Cancer Center-West Lakes

City

Clive

State/Province

Iowa

ZIP/Postal Code

50325

Country

United States

Individual Site Status

Suspended

Facility Name

Greater Regional Medical Center

City

Creston

State/Province

Iowa

ZIP/Postal Code

50801

Country

United States

Individual Site Status

Suspended

Facility Name

Mercy Medical Center - Des Moines

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50314

Country

United States

Individual Site Status

Suspended

Facility Name

Mission Cancer and Blood - Laurel

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50314

Country

United States

Individual Site Status

Suspended

Facility Name

Mercy Medical Center-West Lakes

City

West Des Moines

State/Province

Iowa

ZIP/Postal Code

50266

Country

United States

Individual Site Status

Suspended

Facility Name

Ochsner Medical Center Jefferson

City

New Orleans

State/Province

Louisiana

ZIP/Postal Code

70121

Country

United States

Individual Site Status

Suspended

Facility Name

Lafayette Family Cancer Center-EMMC

City

Brewer

State/Province

Maine

ZIP/Postal Code

04412

Country

United States

Individual Site Status

Suspended

Facility Name

Sinai Hospital of Baltimore

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21215

Country

United States

Individual Site Status

Suspended

Facility Name

Boston Medical Center

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02118

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph Mercy Hospital

City

Ann Arbor

State/Province

Michigan

ZIP/Postal Code

48106

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph Mercy Brighton

City

Brighton

State/Province

Michigan

ZIP/Postal Code

48114

Country

United States

Individual Site Status

Suspended

Facility Name

Trinity Health IHA Medical Group Hematology Oncology - Brighton

City

Brighton

State/Province

Michigan

ZIP/Postal Code

48114

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph Mercy Canton

City

Canton

State/Province

Michigan

ZIP/Postal Code

48188

Country

United States

Individual Site Status

Suspended

Facility Name

Trinity Health IHA Medical Group Hematology Oncology - Canton

City

Canton

State/Province

Michigan

ZIP/Postal Code

48188

Country

United States

Individual Site Status

Suspended

Facility Name

Caro Cancer Center

City

Caro

State/Province

Michigan

ZIP/Postal Code

48723

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph Mercy Chelsea

City

Chelsea

State/Province

Michigan

ZIP/Postal Code

48118

Country

United States

Individual Site Status

Suspended

Facility Name

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

City

Chelsea

State/Province

Michigan

ZIP/Postal Code

48118

Country

United States

Individual Site Status

Suspended

Facility Name

Beaumont Hospital - Dearborn

City

Dearborn

State/Province

Michigan

ZIP/Postal Code

48124

Country

United States

Individual Site Status

Suspended

Facility Name

Beaumont Hospital - Farmington Hills

City

Farmington Hills

State/Province

Michigan

ZIP/Postal Code

48336

Country

United States

Individual Site Status

Suspended

Facility Name

Genesys Hurley Cancer Institute

City

Flint

State/Province

Michigan

ZIP/Postal Code

48503

Country

United States

Individual Site Status

Suspended

Facility Name

Hurley Medical Center

City

Flint

State/Province

Michigan

ZIP/Postal Code

48503

Country

United States

Individual Site Status

Suspended

Facility Name

Sparrow Hospital

City

Lansing

State/Province

Michigan

ZIP/Postal Code

48912

Country

United States

Individual Site Status

Suspended

Facility Name

Trinity Health Saint Mary Mercy Livonia Hospital

City

Livonia

State/Province

Michigan

ZIP/Postal Code

48154

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Mary's Oncology/Hematology Associates of Marlette

City

Marlette

State/Province

Michigan

ZIP/Postal Code

48453

Country

United States

Individual Site Status

Suspended

Facility Name

21st Century Oncology-Pontiac

City

Pontiac

State/Province

Michigan

ZIP/Postal Code

48341

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Joseph Mercy Oakland

City

Pontiac

State/Province

Michigan

ZIP/Postal Code

48341

Country

United States

Individual Site Status

Suspended

Facility Name

William Beaumont Hospital-Royal Oak

City

Royal Oak

State/Province

Michigan

ZIP/Postal Code

48073

Country

United States

Individual Site Status

Suspended

Facility Name

Ascension Saint Mary's Hospital

City

Saginaw

State/Province

Michigan

ZIP/Postal Code

48601

Country

United States

Individual Site Status

Suspended

Facility Name

Oncology Hematology Associates of Saginaw Valley PC

City

Saginaw

State/Province

Michigan

ZIP/Postal Code

48604

Country

United States

Individual Site Status

Suspended

Facility Name

Ascension Saint Joseph Hospital

City

Tawas City

State/Province

Michigan

ZIP/Postal Code

48764

Country

United States

Individual Site Status

Suspended

Facility Name

William Beaumont Hospital - Troy

City

Troy

State/Province

Michigan

ZIP/Postal Code

48085

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Mary's Oncology/Hematology Associates of West Branch

City

West Branch

State/Province

Michigan

ZIP/Postal Code

48661

Country

United States

Individual Site Status

Suspended

Facility Name

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

City

Ypsilanti

State/Province

Michigan

ZIP/Postal Code

48197

Country

United States

Individual Site Status

Suspended

Facility Name

Sanford Joe Lueken Cancer Center

City

Bemidji

State/Province

Minnesota

ZIP/Postal Code

56601

Country

United States

Individual Site Status

Suspended

Facility Name

Minnesota Oncology - Burnsville

City

Burnsville

State/Province

Minnesota

ZIP/Postal Code

55337

Country

United States

Individual Site Status

Suspended

Facility Name

Minnesota Oncology Hematology PA-Maplewood

City

Maplewood

State/Province

Minnesota

ZIP/Postal Code

55109

Country

United States

Individual Site Status

Suspended

Facility Name

Abbott-Northwestern Hospital

City

Minneapolis

State/Province

Minnesota

ZIP/Postal Code

55407

Country

United States

Individual Site Status

Suspended

Facility Name

United Hospital

City

Saint Paul

State/Province

Minnesota

ZIP/Postal Code

55102

Country

United States

Individual Site Status

Suspended

Facility Name

Minnesota Oncology Hematology PA-Woodbury

City

Woodbury

State/Province

Minnesota

ZIP/Postal Code

55125

Country

United States

Individual Site Status

Suspended

Facility Name

Baptist Memorial Hospital and Cancer Center-Golden Triangle

City

Columbus

State/Province

Mississippi

ZIP/Postal Code

39705

Country

United States

Individual Site Status

Suspended

Facility Name

Baptist Cancer Center-Grenada

City

Grenada

State/Province

Mississippi

ZIP/Postal Code

38901

Country

United States

Individual Site Status

Suspended

Facility Name

Baptist Memorial Hospital and Cancer Center-Union County

City

New Albany

State/Province

Mississippi

ZIP/Postal Code

38652

Country

United States

Individual Site Status

Suspended

Facility Name

Baptist Memorial Hospital and Cancer Center-Oxford

City

Oxford

State/Province

Mississippi

ZIP/Postal Code

38655

Country

United States

Individual Site Status

Suspended

Facility Name

Baptist Memorial Hospital and Cancer Center-Desoto

City

Southhaven

State/Province

Mississippi

ZIP/Postal Code

38671

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Francis Medical Center

City

Cape Girardeau

State/Province

Missouri

ZIP/Postal Code

63703

Country

United States

Individual Site Status

Suspended

Facility Name

Delbert Day Cancer Institute at PCRMC

City

Rolla

State/Province

Missouri

ZIP/Postal Code

65401

Country

United States

Individual Site Status

Suspended

Facility Name

Mercy Clinic-Rolla-Cancer and Hematology

City

Rolla

State/Province

Missouri

ZIP/Postal Code

65401

Country

United States

Individual Site Status

Suspended

Facility Name

Mercy Hospital Saint Louis

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63141

Country

United States

Individual Site Status

Suspended

Facility Name

CoxHealth South Hospital

City

Springfield

State/Province

Missouri

ZIP/Postal Code

65807

Country

United States

Individual Site Status

Suspended

Facility Name

OptumCare Cancer Care at Seven Hills

City

Henderson

State/Province

Nevada

ZIP/Postal Code

89052

Country

United States

Individual Site Status

Suspended

Facility Name

OptumCare Cancer Care at Charleston

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89102

Country

United States

Individual Site Status

Suspended

Facility Name

Radiation Oncology Centers of Nevada Central

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89106

Country

United States

Individual Site Status

Suspended

Facility Name

Radiation Oncology Centers of Nevada Southeast

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89119

Country

United States

Individual Site Status

Suspended

Facility Name

OptumCare Cancer Care at MountainView

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89128

Country

United States

Individual Site Status

Suspended

Facility Name

Alliance for Childhood Diseases/Cure 4 the Kids Foundation

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89135

Country

United States

Individual Site Status

Suspended

Facility Name

Comprehensive Cancer Centers of Nevada

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89148

Country

United States

Individual Site Status

Suspended

Facility Name

OptumCare Cancer Care at Fort Apache

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89148

Country

United States

Individual Site Status

Suspended

Facility Name

Renown Regional Medical Center

City

Reno

State/Province

Nevada

ZIP/Postal Code

89502

Country

United States

Individual Site Status

Suspended

Facility Name

New Hampshire Oncology Hematology PA-Concord

City

Concord

State/Province

New Hampshire

ZIP/Postal Code

03301

Country

United States

Individual Site Status

Suspended

Facility Name

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

City

Lebanon

State/Province

New Hampshire

ZIP/Postal Code

03756

Country

United States

Individual Site Status

Suspended

Facility Name

The Dana-Farber Cancer Institute at Londonderry

City

Londonderry

State/Province

New Hampshire

ZIP/Postal Code

03053

Country

United States

Individual Site Status

Suspended

Facility Name

Solinsky Center for Cancer Care

City

Manchester

State/Province

New Hampshire

ZIP/Postal Code

03103

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Sloan Kettering Basking Ridge

City

Basking Ridge

State/Province

New Jersey

ZIP/Postal Code

07920

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Sloan Kettering Monmouth

City

Middletown

State/Province

New Jersey

ZIP/Postal Code

07748

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Sloan Kettering Bergen

City

Montvale

State/Province

New Jersey

ZIP/Postal Code

07645

Country

United States

Individual Site Status

Suspended

Facility Name

Holy Name Hospital

City

Teaneck

State/Province

New Jersey

ZIP/Postal Code

07666

Country

United States

Individual Site Status

Suspended

Facility Name

Montefiore Medical Center-Einstein Campus

City

Bronx

State/Province

New York

ZIP/Postal Code

10461

Country

United States

Individual Site Status

Suspended

Facility Name

Montefiore Medical Center-Weiler Hospital

City

Bronx

State/Province

New York

ZIP/Postal Code

10461

Country

United States

Individual Site Status

Suspended

Facility Name

Montefiore Medical Center - Moses Campus

City

Bronx

State/Province

New York

ZIP/Postal Code

10467

Country

United States

Individual Site Status

Suspended

Facility Name

Roswell Park Cancer Institute

City

Buffalo

State/Province

New York

ZIP/Postal Code

14263

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Sloan Kettering Commack

City

Commack

State/Province

New York

ZIP/Postal Code

11725

Country

United States

Individual Site Status

Suspended

Facility Name

Northwell Health Cancer Institute at Huntington

City

Greenlawn

State/Province

New York

ZIP/Postal Code

11740

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Sloan Kettering Westchester

City

Harrison

State/Province

New York

ZIP/Postal Code

10604

Country

United States

Individual Site Status

Suspended

Facility Name

Northwell Health/Center for Advanced Medicine

City

Lake Success

State/Province

New York

ZIP/Postal Code

11042

Country

United States

Individual Site Status

Suspended

Facility Name

NYU Winthrop Hospital

City

Mineola

State/Province

New York

ZIP/Postal Code

11501

Country

United States

Individual Site Status

Suspended

Facility Name

Laura and Isaac Perlmutter Cancer Center at NYU Langone

City

New York

State/Province

New York

ZIP/Postal Code

10016

Country

United States

Individual Site Status

Suspended

Facility Name

Mount Sinai West

City

New York

State/Province

New York

ZIP/Postal Code

10019

Country

United States

Individual Site Status

Suspended

Facility Name

Lenox Hill Hospital

City

New York

State/Province

New York

ZIP/Postal Code

10021

Country

United States

Individual Site Status

Suspended

Facility Name

Mount Sinai Hospital

City

New York

State/Province

New York

ZIP/Postal Code

10029

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Sloan Kettering Cancer Center

City

New York

State/Province

New York

ZIP/Postal Code

10065

Country

United States

Individual Site Status

Suspended

Facility Name

University of Rochester

City

Rochester

State/Province

New York

ZIP/Postal Code

14642

Country

United States

Individual Site Status

Suspended

Facility Name

Memorial Sloan Kettering Nassau

City

Uniondale

State/Province

New York

ZIP/Postal Code

11553

Country

United States

Individual Site Status

Suspended

Facility Name

Wilmot Cancer Institute at Webster

City

Webster

State/Province

New York

ZIP/Postal Code

14580

Country

United States

Individual Site Status

Suspended

Facility Name

Duke Cancer Institute Cary

City

Cary

State/Province

North Carolina

ZIP/Postal Code

27518

Country

United States

Individual Site Status

Suspended

Facility Name

UNC Lineberger Comprehensive Cancer Center

City

Chapel Hill

State/Province

North Carolina

ZIP/Postal Code

27599

Country

United States

Individual Site Status

Suspended

Facility Name

Wake Forest University at Clemmons

City

Clemmons

State/Province

North Carolina

ZIP/Postal Code

27012

Country

United States

Individual Site Status

Suspended

Facility Name

Duke University Medical Center

City

Durham

State/Province

North Carolina

ZIP/Postal Code

27710

Country

United States

Individual Site Status

Suspended

Facility Name

East Carolina University

City

Greenville

State/Province

North Carolina

ZIP/Postal Code

27834

Country

United States

Individual Site Status

Suspended

Facility Name

Duke Raleigh Hospital

City

Raleigh

State/Province

North Carolina

ZIP/Postal Code

27609

Country

United States

Individual Site Status

Suspended

Facility Name

Wake Forest Baptist Health - Wilkes Medical Center

City

Wilkesboro

State/Province

North Carolina

ZIP/Postal Code

28659

Country

United States

Individual Site Status

Suspended

Facility Name

Wake Forest University Health Sciences

City

Winston-Salem

State/Province

North Carolina

ZIP/Postal Code

27157

Country

United States

Individual Site Status

Suspended

Facility Name

Sanford Bismarck Medical Center

City

Bismarck

State/Province

North Dakota

ZIP/Postal Code

58501

Country

United States

Individual Site Status

Suspended

Facility Name

Sanford Broadway Medical Center

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58122

Country

United States

Individual Site Status

Suspended

Facility Name

Sanford Roger Maris Cancer Center

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58122

Country

United States

Individual Site Status

Suspended

Facility Name

MetroHealth Medical Center

City

Cleveland

State/Province

Ohio

ZIP/Postal Code

44109

Country

United States

Individual Site Status

Suspended

Facility Name

Ohio State University Comprehensive Cancer Center

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43210

Country

United States

Individual Site Status

Suspended

Facility Name

University of Oklahoma Health Sciences Center

City

Oklahoma City

State/Province

Oklahoma

ZIP/Postal Code

73104

Country

United States

Individual Site Status

Suspended

Facility Name

Mercy Hospital Oklahoma City

City

Oklahoma City

State/Province

Oklahoma

ZIP/Postal Code

73120

Country

United States

Individual Site Status

Suspended

Facility Name

Clackamas Radiation Oncology Center

City

Clackamas

State/Province

Oregon

ZIP/Postal Code

97015

Country

United States

Individual Site Status

Suspended

Facility Name

Providence Cancer Institute Clackamas Clinic

City

Clackamas

State/Province

Oregon

ZIP/Postal Code

97015

Country

United States

Individual Site Status

Suspended

Facility Name

Providence Newberg Medical Center

City

Newberg

State/Province

Oregon

ZIP/Postal Code

97132

Country

United States

Individual Site Status

Suspended

Facility Name

Providence Willamette Falls Medical Center

City

Oregon City

State/Province

Oregon

ZIP/Postal Code

97045

Country

United States

Individual Site Status

Suspended

Facility Name

Providence Portland Medical Center

City

Portland

State/Province

Oregon

ZIP/Postal Code

97213

Country

United States

Individual Site Status

Suspended

Facility Name

Providence Saint Vincent Medical Center

City

Portland

State/Province

Oregon

ZIP/Postal Code

97225

Country

United States

Individual Site Status

Suspended

Facility Name

Lehigh Valley Hospital-Cedar Crest

City

Allentown

State/Province

Pennsylvania

ZIP/Postal Code

18103

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Altoona

City

Altoona

State/Province

Pennsylvania

ZIP/Postal Code

16601

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Camp Hill

City

Camp Hill

State/Province

Pennsylvania

ZIP/Postal Code

17011

Country

United States

Individual Site Status

Suspended

Facility Name

Carlisle Regional Cancer Center

City

Carlisle

State/Province

Pennsylvania

ZIP/Postal Code

17015

Country

United States

Individual Site Status

Suspended

Facility Name

Christiana Care Health System-Concord Health Center

City

Chadds Ford

State/Province

Pennsylvania

ZIP/Postal Code

19317

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Hillman Cancer Center Erie

City

Erie

State/Province

Pennsylvania

ZIP/Postal Code

16505

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Vincent Hospital

City

Erie

State/Province

Pennsylvania

ZIP/Postal Code

16544

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Cancer Center at UPMC Horizon

City

Farrell

State/Province

Pennsylvania

ZIP/Postal Code

16121

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Cancer Centers - Arnold Palmer Pavilion

City

Greensburg

State/Province

Pennsylvania

ZIP/Postal Code

15601

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Pinnacle Cancer Center/Community Osteopathic Campus

City

Harrisburg

State/Province

Pennsylvania

ZIP/Postal Code

17109

Country

United States

Individual Site Status

Suspended

Facility Name

Penn State Milton S Hershey Medical Center

City

Hershey

State/Province

Pennsylvania

ZIP/Postal Code

17033-0850

Country

United States

Individual Site Status

Suspended

Facility Name

IRMC Cancer Center

City

Indiana

State/Province

Pennsylvania

ZIP/Postal Code

15701

Country

United States

Individual Site Status

Suspended

Facility Name

Jefferson Hospital

City

Jefferson Hills

State/Province

Pennsylvania

ZIP/Postal Code

15025

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC-Johnstown/John P. Murtha Regional Cancer Center

City

Johnstown

State/Province

Pennsylvania

ZIP/Postal Code

15901

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion

City

Mechanicsburg

State/Province

Pennsylvania

ZIP/Postal Code

17050

Country

United States

Individual Site Status

Suspended

Facility Name

Forbes Hospital

City

Monroeville

State/Province

Pennsylvania

ZIP/Postal Code

15146

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Hillman Cancer Center - Part of Frick Hospital

City

Mount Pleasant

State/Province

Pennsylvania

ZIP/Postal Code

15666

Country

United States

Individual Site Status

Suspended

Facility Name

Arnold Palmer Cancer Center Medical Oncology Norwin

City

N. Huntingdon

State/Province

Pennsylvania

ZIP/Postal Code

15642

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Hillman Cancer Center - New Castle

City

New Castle

State/Province

Pennsylvania

ZIP/Postal Code

16105

Country

United States

Individual Site Status

Suspended

Facility Name

Thomas Jefferson University Hospital

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19107

Country

United States

Individual Site Status

Suspended

Facility Name

Allegheny General Hospital

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15212

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC-Saint Margaret

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15215

Country

United States

Individual Site Status

Suspended

Facility Name

University of Pittsburgh Cancer Institute (UPCI)

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15232

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC-Shadyside Hospital

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15232

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC-Passavant Hospital

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15237

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC-Saint Clair Hospital Cancer Center

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15243

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Cancer Center at UPMC Northwest

City

Seneca

State/Province

Pennsylvania

ZIP/Postal Code

16346

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Cancer Center-Washington

City

Washington

State/Province

Pennsylvania

ZIP/Postal Code

15301

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Washington Hospital Radiation Oncology

City

Washington

State/Province

Pennsylvania

ZIP/Postal Code

15301

Country

United States

Individual Site Status

Suspended

Facility Name

Chester County Hospital

City

West Chester

State/Province

Pennsylvania

ZIP/Postal Code

19380

Country

United States

Individual Site Status

Suspended

Facility Name

Wexford Health and Wellness Pavilion

City

Wexford

State/Province

Pennsylvania

ZIP/Postal Code

15090

Country

United States

Individual Site Status

Suspended

Facility Name

Divine Providence Hospital

City

Williamsport

State/Province

Pennsylvania

ZIP/Postal Code

17754

Country

United States

Individual Site Status

Suspended

Facility Name

Asplundh Cancer Pavilion

City

Willow Grove

State/Province

Pennsylvania

ZIP/Postal Code

19090

Country

United States

Individual Site Status

Suspended

Facility Name

UPMC Memorial

City

York

State/Province

Pennsylvania

ZIP/Postal Code

17408

Country

United States

Individual Site Status

Suspended

Facility Name

Medical University of South Carolina

City

Charleston

State/Province

South Carolina

ZIP/Postal Code

29425

Country

United States

Individual Site Status

Suspended

Facility Name

Gibbs Cancer Center-Gaffney

City

Gaffney

State/Province

South Carolina

ZIP/Postal Code

29341

Country

United States

Individual Site Status

Suspended

Facility Name

Tidelands Georgetown Memorial Hospital

City

Georgetown

State/Province

South Carolina

ZIP/Postal Code

29440

Country

United States

Individual Site Status

Suspended

Facility Name

Prisma Health Cancer Institute - Faris

City

Greenville

State/Province

South Carolina

ZIP/Postal Code

29605

Country

United States

Individual Site Status

Suspended

Facility Name

Prisma Health Cancer Institute - Eastside

City

Greenville

State/Province

South Carolina

ZIP/Postal Code

29615

Country

United States

Individual Site Status

Suspended

Facility Name

Prisma Health Cancer Institute - Greer

City

Greer

State/Province

South Carolina

ZIP/Postal Code

29650

Country

United States

Individual Site Status

Suspended

Facility Name

Gibbs Cancer Center-Pelham

City

Greer

State/Province

South Carolina

ZIP/Postal Code

29651

Country

United States

Individual Site Status

Suspended

Facility Name

MUSC Health Tidelands Health Radiation Therapy Center

City

Murrells Inlet

State/Province

South Carolina

ZIP/Postal Code

29576

Country

United States

Individual Site Status

Suspended

Facility Name

Prisma Health Cancer Institute - Seneca

City

Seneca

State/Province

South Carolina

ZIP/Postal Code

29672

Country

United States

Individual Site Status

Suspended

Facility Name

Spartanburg Medical Center

City

Spartanburg

State/Province

South Carolina

ZIP/Postal Code

29303

Country

United States

Individual Site Status

Suspended

Facility Name

MGC Hematology Oncology-Union

City

Union

State/Province

South Carolina

ZIP/Postal Code

29379

Country

United States

Individual Site Status

Suspended

Facility Name

Lexington Medical Center

City

West Columbia

State/Province

South Carolina

ZIP/Postal Code

29169

Country

United States

Individual Site Status

Suspended

Facility Name

Sanford Cancer Center Oncology Clinic

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57104

Country

United States

Individual Site Status

Suspended

Facility Name

Avera Cancer Institute

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57105

Country

United States

Individual Site Status

Suspended

Facility Name

Sanford USD Medical Center - Sioux Falls

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57117-5134

Country

United States

Individual Site Status

Suspended

Facility Name

Avera Cancer Institute at Yankton

City

Yankton

State/Province

South Dakota

ZIP/Postal Code

57078

Country

United States

Individual Site Status

Suspended

Facility Name

Baptist Memorial Hospital and Cancer Center-Collierville

City

Collierville

State/Province

Tennessee

ZIP/Postal Code

38017

Country

United States

Individual Site Status

Suspended

Facility Name

The West Clinic - Wolf River

City

Germantown

State/Province

Tennessee

ZIP/Postal Code

38138

Country

United States

Individual Site Status

Suspended

Facility Name

Baptist Memorial Hospital and Cancer Center-Memphis

City

Memphis

State/Province

Tennessee

ZIP/Postal Code

38120

Country

United States

Individual Site Status

Suspended

Facility Name

Vanderbilt Breast Center at One Hundred Oaks

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37204

Country

United States

Individual Site Status

Suspended

Facility Name

Vanderbilt University/Ingram Cancer Center

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37232

Country

United States

Individual Site Status

Suspended

Facility Name

The Don and Sybil Harrington Cancer Center

City

Amarillo

State/Province

Texas

ZIP/Postal Code

79106

Country

United States

Individual Site Status

Suspended

Facility Name

Lyndon Baines Johnson General Hospital

City

Houston

State/Province

Texas

ZIP/Postal Code

77026-1967

Country

United States

Individual Site Status

Suspended

Facility Name

M D Anderson Cancer Center

City

Houston

State/Province

Texas

ZIP/Postal Code

77030

Country

United States

Individual Site Status

Suspended

Facility Name

University of Texas Health Science Center at San Antonio

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78229

Country

United States

Individual Site Status

Suspended

Facility Name

Farmington Health Center

City

Farmington

State/Province

Utah

ZIP/Postal Code

84025

Country

United States

Individual Site Status

Suspended

Facility Name

University of Utah Sugarhouse Health Center

City

Salt Lake City

State/Province

Utah

ZIP/Postal Code

84106

Country

United States

Individual Site Status

Suspended

Facility Name

Huntsman Cancer Institute/University of Utah

City

Salt Lake City

State/Province

Utah

ZIP/Postal Code

84112

Country

United States

Individual Site Status

Suspended

Facility Name

Inova Schar Cancer Institute

City

Fairfax

State/Province

Virginia

ZIP/Postal Code

22031

Country

United States

Individual Site Status

Recruiting

Facility Contact:

First Name & Middle Initial & Last Name & Degree

Site Public Contact

Phone

703-720-5210

Stephanie.VanBebber@inova.org

First Name & Middle Initial & Last Name & Degree

Jasmine Huynh

Facility Name

Inova Fair Oaks Hospital

City

Fairfax

State/Province

Virginia

ZIP/Postal Code

22033

Country

United States

Individual Site Status

Recruiting

Facility Contact:

First Name & Middle Initial & Last Name & Degree

Site Public Contact

Phone

703-720-5210

Stephanie.VanBebber@inova.org

First Name & Middle Initial & Last Name & Degree

Jasmine Huynh

Facility Name

Inova Fairfax Hospital

City

Falls Church

State/Province

Virginia

ZIP/Postal Code

22042

Country

United States

Individual Site Status

Recruiting

Facility Contact:

First Name & Middle Initial & Last Name & Degree

Site Public Contact

Phone

703-208-6650

Stephanie.VanBebber@inova.org

First Name & Middle Initial & Last Name & Degree

Jasmine Huynh

Facility Name

Inova Loudoun Hospital

City

Leesburg

State/Province

Virginia

ZIP/Postal Code

20176

Country

United States

Individual Site Status

Recruiting

Facility Contact:

First Name & Middle Initial & Last Name & Degree

Site Public Contact

Phone

703-858-6000

Keary.janet@inova.org

First Name & Middle Initial & Last Name & Degree

Jasmine Huynh

Facility Name

Virginia Cancer Institute

City

Richmond

State/Province

Virginia

ZIP/Postal Code

23229

Country

United States

Individual Site Status

Suspended

Facility Name

VCU Massey Cancer Center at Stony Point

City

Richmond

State/Province

Virginia

ZIP/Postal Code

23235

Country

United States

Individual Site Status

Suspended

Facility Name

Virginia Commonwealth University/Massey Cancer Center

City

Richmond

State/Province

Virginia

ZIP/Postal Code

23298

Country

United States

Individual Site Status

Suspended

Facility Name

Valley Medical Center

City

Renton

State/Province

Washington

ZIP/Postal Code

98055

Country

United States

Individual Site Status

Suspended

Facility Name

Virginia Mason Medical Center

City

Seattle

State/Province

Washington

ZIP/Postal Code

98101

Country

United States

Individual Site Status

Recruiting

Facility Contact:

First Name & Middle Initial & Last Name & Degree

Site Public Contact

Phone

206-287-6275

cancerresearch@virginiamason.org

First Name & Middle Initial & Last Name & Degree

Huong T. Pham

Facility Name

FHCC South Lake Union

City

Seattle

State/Province

Washington

ZIP/Postal Code

98109

Country

United States

Individual Site Status

Suspended

Facility Name

Fred Hutchinson Cancer Research Center

City

Seattle

State/Province

Washington

ZIP/Postal Code

98109

Country

United States

Individual Site Status

Suspended

Facility Name

University of Washington Medical Center - Montlake

City

Seattle

State/Province

Washington

ZIP/Postal Code

98195

Country

United States

Individual Site Status

Suspended

Facility Name

Langlade Hospital and Cancer Center

City

Antigo

State/Province

Wisconsin

ZIP/Postal Code

54409

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Cancer Care-Southern Lakes VLCC

City

Burlington

State/Province

Wisconsin

ZIP/Postal Code

53105

Country

United States

Individual Site Status

Suspended

Facility Name

Marshfield Medical Center-EC Cancer Center

City

Eau Claire

State/Province

Wisconsin

ZIP/Postal Code

54701

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Health Care Germantown Health Center

City

Germantown

State/Province

Wisconsin

ZIP/Postal Code

53022

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Cancer Care-Grafton

City

Grafton

State/Province

Wisconsin

ZIP/Postal Code

53024

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Vincent Hospital Cancer Center Green Bay

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54301

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Vincent Hospital Cancer Center at Saint Mary's

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54303

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora BayCare Medical Center

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54311

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Cancer Care-Kenosha South

City

Kenosha

State/Province

Wisconsin

ZIP/Postal Code

53142

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Bay Area Medical Group-Marinette

City

Marinette

State/Province

Wisconsin

ZIP/Postal Code

54143

Country

United States

Individual Site Status

Suspended

Facility Name

Marshfield Medical Center-Marshfield

City

Marshfield

State/Province

Wisconsin

ZIP/Postal Code

54449

Country

United States

Individual Site Status

Suspended

Facility Name

Froedtert Menomonee Falls Hospital

City

Menomonee Falls

State/Province

Wisconsin

ZIP/Postal Code

53051

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Cancer Care-Milwaukee

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53209

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Saint Luke's Medical Center

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53215

Country

United States

Individual Site Status

Suspended

Facility Name

Medical College of Wisconsin

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53226

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Sinai Medical Center

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53233

Country

United States

Individual Site Status

Suspended

Facility Name

Marshfield Clinic-Minocqua Center

City

Minocqua

State/Province

Wisconsin

ZIP/Postal Code

54548

Country

United States

Individual Site Status

Suspended

Facility Name

Drexel Town Square Health Center

City

Oak Creek

State/Province

Wisconsin

ZIP/Postal Code

53154

Country

United States

Individual Site Status

Suspended

Facility Name

Vince Lombardi Cancer Clinic - Oshkosh

City

Oshkosh

State/Province

Wisconsin

ZIP/Postal Code

54904

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Cancer Care-Racine

City

Racine

State/Province

Wisconsin

ZIP/Postal Code

53406

Country

United States

Individual Site Status

Suspended

Facility Name

Marshfield Medical Center-Rice Lake

City

Rice Lake

State/Province

Wisconsin

ZIP/Postal Code

54868

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Vincent Hospital Cancer Center at Sheboygan

City

Sheboygan

State/Province

Wisconsin

ZIP/Postal Code

53081

Country

United States

Individual Site Status

Suspended

Facility Name

Vince Lombardi Cancer Clinic-Sheboygan

City

Sheboygan

State/Province

Wisconsin

ZIP/Postal Code

53081

Country

United States

Individual Site Status

Suspended

Facility Name

Ascension Saint Michael's Hospital

City

Stevens Point

State/Province

Wisconsin

ZIP/Postal Code

54481

Country

United States

Individual Site Status

Suspended

Facility Name

Marshfield Medical Center-River Region at Stevens Point

City

Stevens Point

State/Province

Wisconsin

ZIP/Postal Code

54482

Country

United States

Individual Site Status

Suspended

Facility Name

Saint Vincent Hospital Cancer Center at Sturgeon Bay

City

Sturgeon Bay

State/Province

Wisconsin

ZIP/Postal Code

54235-1495

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Medical Center in Summit

City

Summit

State/Province

Wisconsin

ZIP/Postal Code

53066

Country

United States

Individual Site Status

Suspended

Facility Name

Vince Lombardi Cancer Clinic-Two Rivers

City

Two Rivers

State/Province

Wisconsin

ZIP/Postal Code

54241

Country

United States

Individual Site Status

Suspended

Facility Name

Aspirus Regional Cancer Center

City

Wausau

State/Province

Wisconsin

ZIP/Postal Code

54401

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora Cancer Care-Milwaukee West

City

Wauwatosa

State/Province

Wisconsin

ZIP/Postal Code

53226

Country

United States

Individual Site Status

Suspended

Facility Name

Aurora West Allis Medical Center

City

West Allis

State/Province

Wisconsin

ZIP/Postal Code

53227

Country

United States

Individual Site Status

Suspended

Facility Name

Froedtert West Bend Hospital/Kraemer Cancer Center

City

West Bend

State/Province

Wisconsin

ZIP/Postal Code

53095

Country

United States

Individual Site Status

Suspended

Facility Name

Marshfield Medical Center - Weston

City

Weston

State/Province

Wisconsin

ZIP/Postal Code

54476

Country

United States

Individual Site Status

Suspended

Facility Name

Aspirus Cancer Care - Wisconsin Rapids

City

Wisconsin Rapids

State/Province

Wisconsin

ZIP/Postal Code

54494

Country

United States

Individual Site Status

Suspended

12. IPD Sharing Statement

Plan to Share IPD

Yes

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