Colonoscopy vs Stool Testing for Older Adults With Colon Polyps (COOP)
Colorectal Polyp, Colorectal Neoplasms, Colorectal Adenoma
About this trial
This is an interventional prevention trial for Colorectal Polyp focused on measuring Colonoscopy, Fecal immunochemical test (FIT)
Eligibility Criteria
Inclusion Criteria: English or Spanish speaking Personal history of colorectal polyps Most recent colonoscopy with ≤2 non-advanced polyps Currently due or coming due within 12 months for colonoscopy Able to provide written informed consent Exclusion Criteria: Personal history of colorectal cancer Personal history of genetic syndrome with high risk for colorectal cancer (e.g. Lynch Syndrome, Familial Adenomatous Polyposis Syndrome (FAP), or Serrated Polyposis Syndrome) Personal history of inflammatory bowel disease (e.g. ulcerative colitis, Crohn's disease) Most recent colonoscopy with advanced polyp(s) or ≥3 non-advanced polyps Patients unlikely to benefit from polyp surveillance (e.g., history of heart disease or coronary artery disease with treatment in the last 6 months, heart failure affecting function, lung disease requiring use of home oxygen, stroke within the last 4 months, dementia affecting activities of daily living (ADL) or instrumental activities of daily living (IADL), severe liver disease requiring the use of certain medications to control fluid, confusion, or bleeding, severe kidney disease requiring dialysis, or a new cancer diagnosis within the last year) Patients with an existing, scheduled appointment for surveillance colonoscopy Patients unable to provide written informed consent Patients who lack a valid mailing address
Sites / Locations
- University of Alabama BirminghamRecruiting
- Kaiser Permanente Northern CaliforniaRecruiting
- University of ColoradoRecruiting
- Dartmouth HealthRecruiting
- Kaiser Permanente NorthwestRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
FIT
Colonoscopy
FIT (annual)
Surveillance colonoscopy (one time)