Brain Effect Mechanism of Lever Positioning Manipulation on LDH Analgesia Based on Multimodal MRI
Lumbar Disc Herniation, Multimodal Brain Function, Analgesia Mechanism
About this trial
This is an interventional treatment trial for Lumbar Disc Herniation
Eligibility Criteria
Inclusion Criteria: patients suffering from low back pain and/or radicular leg pain; persistent pain for at least six months that was nonresponsive to conservative treatments; at least one epidural or facet joint corticosteroid injection in the last past year without pain relief or with an improvement in pain of less than two months. Lumbar protrusion level discopathy on MRI corresponding to the level of pain. No interventional pain treatment was applied within the last three months and patients needed a pain score equal or greater than four on the visual analogic scale (VAS). - Exclusion Criteria: 1.patients with motor deficits, systemic infection, coagulation disorders, pregnancy; 2.VAS pain score lower than four; 3.Patients with any other condition that prevents an MRI scan from being performed. -
Sites / Locations
- The Third Affiliated Hospital of Zhejiang Chinese Medical University
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
No Intervention
Group1 (lever positioning manipulation)
Group2 (placebo group)
Group3 (healthy controls)
Patients with lumbar disc herniation treated by lever positioning manipulation
Patients with lumbar disc herniation treated by sham lever positioning manipulation
Healthy control group without any intervention.