Oxygen Targets in Acute Heart Failure With Pulmonary Congestion (REDOX-AHF)
Acute Heart Failure, Pulmonary Congestion, Hypoxemia
About this trial
This is an interventional treatment trial for Acute Heart Failure focused on measuring acute heart failure, Pulmonary edema, Oxygen, Pulmonary congestion
Eligibility Criteria
Inclusion Criteria: Age ≥ 18 years Acute (within minutes to days) onset or worsening of subjective dyspnea Oxygen saturation <92% (on arterial blood gas) or need of oxygen At least one of the following clinical or radiological signs of congestion: 1. Pulmonary rales 2. Chest X-ray or CT with pulmonary congestion 3. Lung ultrasound with multiple B-lines Exclusion Criteria: More than 4 hours from hospital admission to randomization Suspected infection or sepsis Known severe pulmonary disease Systolic blood pressure <90 mmHg
Sites / Locations
- Bispebjerg Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Liberal oxygenation group
Restrictive oxygenation group
SpO2 target of 96%
SpO2 target of 90%.