A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments
Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1, Other Specified Diseases of Hair and Hair Follicles
About this trial
This is an interventional supportive care trial for Mild to Moderate Acne focused on measuring Acne, Wrinkles, Joints pain, brittle nails, hair fall
Eligibility Criteria
Inclusion Criteria: The subject must fulfil all of the following inclusion criteria to be eligible for participation in the study unless otherwise specified. Age: 30 to 50 years (both inclusive) at the time of consent. Sex: Healthy non-pregnant/non-lactating females and Males. Female of childbearing potential must have a reported negative pregnancy during screening and end of the study. Subject is generally in good health. Subject has mild to moderate crows' feet wrinkles. Subject has mild to moderate joints pain, swelling, stiffness and decreased range of motion. Subject has a score of at least "mild skin aging" based on PGA at screening visit. Subject has Glogau Skin Age II or III as assessed by the Dermatologist/ Dermatologist Trained Evaluator. Subject having complaints of hair fall and decreased hair growth. The subject self-declare nonpathological thin, dry, and brittle hair and nails. Subject is willing to forgo cosmetic procedures 3 months prior to and for the duration of the study. Subject is able to follow their normal skin care routines and to refrain from introducing any new skin care products during the study. Subject is able to forgo changes in baseline medications and nutritional supplements, any other collagen peptide powder during the study period. Subject is able to remain on stable doses of contraceptive or replacement hormonal therapy, including no therapy, 6 weeks prior to and for the duration of the study. If the female subject is of childbearing potential, is practicing and agrees to maintain an established method of birth control (IUD, hormonal implant device/injection, regular use of birth control pills or patch, diaphragm, condoms with spermicide or sponge with spermicidal jelly, cream or foam, partner vasectomy or abstinence). Females will be considered as non-childbearing potential if they are surgically sterile, have been post-menopausal for at least 1 year or have had a tubal ligation. If currently using hormonal contraception, has been using this form of contraception for at least 6 months and agrees to continue using the same contraception for the duration of the study. Subject is willing not to introduce any new soaps, cleansers, lotions, creams, or any other face product etc. for the duration of the study. Subject is willing to give written informed consent and are willing to follow the study procedure. Subject is committed not to not to use medicated/ prescription shampoos/hair care products (containing Minoxidil / Anti-thinning agents) or any other hair growth, treatment for thin hair, or hair products other than the test product for the entire duration of the study. The subject is willing to use test treatment throughout the study period. Only For Bovine Arm: Subjects with osteoarthritis patients having present complaints of pain and stiffness in joints (based on their current prescription and medical history). Exclusion Criteria: Subjects must not be enrolled in the study if they meet any one of the following criteria: Subject has a history of allergy or sensitivity to the test treatments ingredients. Subject who has a history of allergy with products containing Fish, Bovine, Chicken, broccoli and carrots. Subject who has pre-existing or dormant dermatologic conditions (e.g., psoriasis rashes, eczema, seborrheic dermatitis, acne or any other) that could interfere with the outcome of the study as determined by the Investigator. Subject has used any systemic therapy with chronic antibiotic therapy, retinoids, and/or oral steroids during the 4 weeks prior to the start or anticipates having to use at any point during the study. Subject has applied any topical retinoids within 2 weeks of the screening visit or anticipates having to use at any point during the study. Subject is not willing to avoid unprotected sun or other UV radiation exposure during the study period. Subject has a history of prior use of hair growth treatment within 3 months. Subject has a history of any prior hair growth procedures (e.g., hair transplant or laser). Subject has a history of alcohol or drug addiction. Subject has plans of shaving scalp hair during the study. Subject is currently participating in or planning on starting a weight loss program that may result in a significant change in overall body weight. Subject has a history of prior use of skin radiance or wrinkle laser treatment within 3 months. Any other condition which could warrant exclusion from the study, as per the dermatologist's/investigator's discretion. Pregnant or breastfeeding or planning to become pregnant during the study period. Subject has a history of chronic illness which may influence the cutaneous state. Subjects participating in other similar nutraceuticals, food, supplemental or therapeutic trials or skin care products within the last four weeks
Sites / Locations
- NovoBliss Research Pvt Ltd
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Experimental
VEGCOL™️ (Veg Collagen Peptide)
PROCOL (Bovine Collagen Peptide)
AQUACOL (Fish | Marine Collagen Peptide)
CALCOL (Chicken Collagen Peptide)
Mode of Usage: 1 scoop/sachet daily Route of Administration: Oral administration with a glassful (approx. 250 mL) of water VEGCOL helps in providing the necessary nutrition needed for the body to produce collagen. Vegan collagen gives a lighter feel on consumption compared to any other collagen and increases the elasticity of the skin and makes skin supple. VEGCOL has more amino acids than animal derived Collagen which makes it very ideal to consume not only in Vegetarian populated countries like in India but around the world. Pepsin, a digestive enzyme, is added to help structure the building blocks into collagen molecules with the exact structure of human collagen.
Bovine collagen is a naturally occurring protein present in the connective tissue, bones, cartilage, and hides of cows. Mode of Usage: 1 scoop/sachet daily Route of Administration: Oral administration with a glassful (approx. 250 mL) of water.
Marine Collagen is made from Fish Skin which delays the signs of aging such as wrinkles, Joint issues and weakness. Mode of Usage: 1 scoop/sachet daily Route of Administration: Oral administration with a glassful (approx. 250 mL) of water.
Chicken collagen is used to treat joint pain associated with many types of arthritis and surgery, as well as back pain, neck pain, and pain following injury. Chicken collagen works by causing participants' body to produce substances that fight inflammation and pain. It also contains chondroitin and glucosamine, two compounds that help rebuild cartilage. That's why chicken collagen can provide some amazing benefits for participants' gut, immune system, skin, and more. Mode of Usage: 1 scoop/sachet daily Route of Administration: Oral administration with a glassful (approx. 250 mL) of water.