Biomarkers Trajectories of Early Intervention in Siblings of Children With Autism Spectrum Disorder
Autism Spectrum Disorder, Early Intervention
About this trial
This is an interventional prevention trial for Autism Spectrum Disorder focused on measuring siblings, autism, biomarkers, early intervention
Eligibility Criteria
Inclusion Criteria: Toddlers aged between 18 and 24 months Toddlers at elevated likelihood of developing autism, because siblings of children with a diagnosis of autism (for group 1, 2, and 3) Exclusion Criteria: Gestational age <36 weeks and/or birthweight < 2000 grams Griffiths general quotient at 18 months < 70 presence of major complications in pregnancy and/or delivery likely to affect brain development presence of neurological deficits, dysmorphic markers, or other medical conditions.
Sites / Locations
- Associazione La Nostra Famiglia - IRCCS Eugenio MedeaRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
No Intervention
No Intervention
No Intervention
Toddlers at elevated likelihood of developing autism with autistic signs, with early intervention
Toddlers at elevated likelihood of developing autism with autistic signs, without early intervention
Toddlers at elevated likelihood of developing autism without autistic signs who received monitoring
Typically developing toddlers who received monitoring
Toddlers at elevated likelihood of developing autism with clinical autistic signs who receive an early intervention from 18 to 24 months
Toddlers at elevated likelihood of developing autism with clinical autistic signs who do not receive an early intervention
Toddlers at elevated likelihood of developing autism without clinical autistic signs who only received assessment and monitoring
Typically developing toddlers who only received assessment and monitoring