Evaluating the Efficacy of Para-discal Infiltration in Patients With Lateralized MODIC 1 Inflammatory Disc Disease (IPAD)
Degenerative Disc Disease, Inflammation, Low Back Pain
About this trial
This is an interventional treatment trial for Degenerative Disc Disease focused on measuring Low back pain, Injections, Degenerative Disc Disease, Inflammation
Eligibility Criteria
Inclusion Criteria: Patient 18 years of age or older Patient with Modic I lateralized disc disease seen on an MRI less than 6 months old. Chronic medial or lateralized (same side as MODIC 1) low back pain for at least 3 months with a mean pain intensity ≥ 40/100 mm on a VAS. Effective contraception for women of childbearing age, at least 6 months after injection (surgical sterilisation, approved hormonal contraceptives, barrier methods, intrauterine intrauterine device) Exclusion Criteria: Patient with MODIC 1 in both underlying and overlying vertebral spaces. Patient with an inflammatory signal abnormality of the vertebral body plateau related to non-mechanical pathology (e.g. spondyloarthritis). Patients with a history of lumbar spine surgery. Patient with suspected spondylodiscitis or other infection. Patients on anticoagulant or antiaggregant therapy, or with a coagulation disorder. Patients with an allergy to iodine or to any of the components of Xylocaine. Patients with an allergy to prednisolone or to any component of Hydrocortancyl® or Dexamethasone®.. Patient with severe uncontrolled disease (i.e. cardiac gastrointestinal, neurological, endocrine, autoimmune) that limits patient safety (as determined by the safety (as judged by the investigator). Prior to the treatment visit : current and recent morphine use (< 1 month) recent systemic or local corticosteroid therapy (< 1 month). Patient with sphincter disturbances indicative of cauda equina syndrome. Psychotic state not controlled by treatment Pregnancy (βHCG positive), breastfeeding Vulnerable patient protected by law Patient under guardianship or curatorship Patient participating in an interventional study Patient unable to read and/or write
Sites / Locations
- Departement of Medical ImagingRecruiting
Arms of the Study
Arm 1
Other
Para-discal infiltration
Single arm study