search
Back to results

Is Strength Training a Viable Exercise Modality for Fat Loss?

Primary Purpose

Overweight and Obesity

Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Diet Only
Training Only
Diet plus Training
Sponsored by
George Washington University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Overweight and Obesity focused on measuring resistance training; metabolism

Eligibility Criteria

25 Years - 40 Years (Adult)FemaleAccepts Healthy Volunteers

Inclusion Criteria: BMI 25-29.9 normally menstruating bodyfat >30% Exclusion Criteria: currently dieting to lose weight currently engaged in structured exercise using dietary weight loss supplements Resting Metabolic Rate not within 10% of predicted value

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm 3

    Arm 4

    Arm Type

    No Intervention

    Experimental

    Experimental

    Experimental

    Arm Label

    Control

    Diet Only

    Training Only

    Diet plus Training

    Arm Description

    No intervention

    Subjects were given calorie and macronutrient intake goals and were told to hit those goals as closely as possible on a daily basis for 16 weeks.

    Subjects were given a 3 times per week supervised resistance training program for 16 weeks

    Subjects were given calorie and macronutrient intake goals and were told to hit those goals as closely as possible on a daily basis for 16 weeks. Subjects were given a 3 times per week supervised resistance training program for 16 weeks

    Outcomes

    Primary Outcome Measures

    Change in Fat Free Mass
    Fat Free Mass as measured from DXA and recorded in Kg
    Change in Fat Mass
    Fat Mass as measured from DXA and recorded in Kg
    Change in Resting Metabolic Rate
    Resting Metabolic Rate measured via indirect calorimetry and recorded in kcal / day
    Change in Visceral Fat
    Fat in the Visceral Depot measured from DXA and recorded in Kg

    Secondary Outcome Measures

    Full Information

    First Posted
    March 19, 2018
    Last Updated
    November 17, 2022
    Sponsor
    George Washington University
    Collaborators
    City University of New York
    search

    1. Study Identification

    Unique Protocol Identification Number
    NCT05622149
    Brief Title
    Is Strength Training a Viable Exercise Modality for Fat Loss?
    Official Title
    Is Strength Training a Viable Exercise Modality for Fat Loss?
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    November 2022
    Overall Recruitment Status
    Completed
    Study Start Date
    March 18, 2016 (Actual)
    Primary Completion Date
    October 1, 2016 (Actual)
    Study Completion Date
    October 1, 2016 (Actual)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    George Washington University
    Collaborators
    City University of New York

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No
    Data Monitoring Committee
    No

    5. Study Description

    Brief Summary
    The purpose of this study is to determine whether strength training can be used as a viable exercise modality for the purpose of inducing fat loss.
    Detailed Description
    Aerobic exercise (AE) is commonly recommended as the most effective exercise modality for weight loss. The Centers for Disease Control (CDC) recommends 150 minutes of AE for weight maintenance, and an unspecified greater amount required for weight loss. Similarly, the American College of Sports Medicine (ACSM) position stand on physical activity for weight loss recommends 150-250 minutes per week of moderate intensity physical activity. While the ACSM promotes resistance training (RT) as a means of increasing fat free mass, which should lead to improved body composition, it does not promote RT for losing significant amounts of body fat. Similarly, the CDC physical activity guidelines for weight loss do not mention RT at all as a viable exercise modality for weight loss. This is not surprising, as there is a paucity of research examining the effects of RT on weight loss. Furthermore, the few studies that have explored RT for weight loss generally show that it is ineffective. The effectiveness of any weight loss program is dependent on the size of the caloric deficit that is created over time, and since AE generally burns more calories per unit of time than RT, it stands to reason that AE would be the most commonly prescribed type of exercise for weight loss. Contributing to the exclusion of RT for weight loss is a widespread belief among dietitians, nutritionists and exercise professionals that it is not possible to induce muscle growth while in a caloric deficit, and since the creation of a caloric deficit is essential for fat loss, the use of RT for muscle growth in a caloric deficit is counter intuitive. However, RT has been shown to elevate resting metabolism for an extended period of time following cessation of the training session. Additionally, having a greater muscle mass should lead to a greater resting metabolism. Unlike RT, chronic AE performed in a caloric deficit (which is often the recommendation for effective weight loss) has the potential to lead to significant decreases in muscle mass, thereby hampering improvements in body composition. Ideally, a program designed to improve body composition should do so through fat losses alone, with muscle mass being maintained or increased. Several reasons could exist for the lack of effectiveness of RT shown in most studies. These reasons include, but are not limited to, 1) Body mass being the measured outcome and not body composition, 2) lack of control and/or measurement of caloric intake, 3) failure to adjust dietary protein needs to support muscle growth, 4) ineffective RT program design. Case studies of clients from our lab have routinely shown that profound decreases in bodyfat can be induced with RT as the exclusive form of exercise. Furthermore, these decreases in bodyfat occur with concomitant increases in muscle mass, while in a caloric deficit. Therefore, the specific aims of this proposal are: To determine whether RT combined with dietary intervention (RT+DIET) results in greater decreases in fat mass than (RT) or dietary intervention (DIET) alone. To determine whether RT combined with dietary intervention (RT+DIET) results in greater improvements in body composition than (RT) or dietary intervention (DIET) alone. To determine whether concomitant increases in muscle mass and decreases in fat mass can occur while in a caloric deficit. The goal of this project is to serve to generate pilot data to determine whether RT can be used as a viable exercise mode for fat loss and muscle gain. We will then pursue funding for a subsequent study that compares the effects of RT versus AE on body composition and fat loss when 1) the caloric intake is monitored to ensure the creation of a caloric deficit, and 2) dietary protein is appropriately increased to support muscle retention/growth.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Overweight and Obesity
    Keywords
    resistance training; metabolism

    7. Study Design

    Primary Purpose
    Treatment
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Masking
    None (Open Label)
    Allocation
    Randomized
    Enrollment
    40 (Actual)

    8. Arms, Groups, and Interventions

    Arm Title
    Control
    Arm Type
    No Intervention
    Arm Description
    No intervention
    Arm Title
    Diet Only
    Arm Type
    Experimental
    Arm Description
    Subjects were given calorie and macronutrient intake goals and were told to hit those goals as closely as possible on a daily basis for 16 weeks.
    Arm Title
    Training Only
    Arm Type
    Experimental
    Arm Description
    Subjects were given a 3 times per week supervised resistance training program for 16 weeks
    Arm Title
    Diet plus Training
    Arm Type
    Experimental
    Arm Description
    Subjects were given calorie and macronutrient intake goals and were told to hit those goals as closely as possible on a daily basis for 16 weeks. Subjects were given a 3 times per week supervised resistance training program for 16 weeks
    Intervention Type
    Behavioral
    Intervention Name(s)
    Diet Only
    Intervention Description
    Food tracking based on macronutrient goals.
    Intervention Type
    Behavioral
    Intervention Name(s)
    Training Only
    Intervention Description
    Subjects completed 16 weeks of supervised resistance training
    Intervention Type
    Behavioral
    Intervention Name(s)
    Diet plus Training
    Intervention Description
    Food tracking plus resistance training.
    Primary Outcome Measure Information:
    Title
    Change in Fat Free Mass
    Description
    Fat Free Mass as measured from DXA and recorded in Kg
    Time Frame
    0 and 16 weeks
    Title
    Change in Fat Mass
    Description
    Fat Mass as measured from DXA and recorded in Kg
    Time Frame
    0, 4, 8, 12, 16 weeks
    Title
    Change in Resting Metabolic Rate
    Description
    Resting Metabolic Rate measured via indirect calorimetry and recorded in kcal / day
    Time Frame
    0 and 16 weeks
    Title
    Change in Visceral Fat
    Description
    Fat in the Visceral Depot measured from DXA and recorded in Kg
    Time Frame
    0, 4, 8, 12, 16 weeks

    10. Eligibility

    Sex
    Female
    Minimum Age & Unit of Time
    25 Years
    Maximum Age & Unit of Time
    40 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: BMI 25-29.9 normally menstruating bodyfat >30% Exclusion Criteria: currently dieting to lose weight currently engaged in structured exercise using dietary weight loss supplements Resting Metabolic Rate not within 10% of predicted value
    Overall Study Officials:
    First Name & Middle Initial & Last Name & Degree
    Todd A Miller, PhD
    Organizational Affiliation
    George Washington University SPH
    Official's Role
    Principal Investigator

    12. IPD Sharing Statement

    Plan to Share IPD
    No

    Learn more about this trial

    Is Strength Training a Viable Exercise Modality for Fat Loss?

    We'll reach out to this number within 24 hrs