The Effect of Intrawound Vancomycin Powder on Surgical Site Infection in Inguinal Lymph Node Dissection
Postoperative Complications
About this trial
This is an interventional prevention trial for Postoperative Complications
Eligibility Criteria
Inclusion Criteria: Women who are undergoing inguinal lymph node dissection for vulvar dysplasia Women with a prior lymph node dissection >30 days before Women undergoing either a sentinel lymph node biopsy or full lymphadenectomy in a unilateral or bilateral groin dissection Exclusion Criteria: Known allergy to vancomycin Known resistance to vancomycin
Sites / Locations
- Women and Infants HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Vancomycin powder
No vancomycin powder
Women randomized to receive vancomycin powder will receive 1g into each of the irrigated inguinal surgical beds (maximum of 2g dose per patient). After dissection and irrigation of the surgical bed, the operating room staff will open the medication vial and sterilely dispense the medication into a sterile container. The surgeon will place the medication powder into the irrigated and hemostatic surgical bed. The procedure will be repeated on the opposite side after dissection.
Patient randomized to the no vancomycin arm will not receive the intraoperative antibiotic. Their surgery will follow standard protocol. No placebo will be utilized.