A Culturally Tailored Dietary Intervention to Treat Crohn's Disease (DAIN)
Crohn Disease
About this trial
This is an interventional treatment trial for Crohn Disease focused on measuring diet, inflammation, microbiome
Eligibility Criteria
Inclusion Criteria: 21 to 65 years old Confirmed Crohn's disease diagnosis is with mild to moderate Crohn's disease symptoms (sCDAI>220 <450) Stable doses of medications are screened; thiopurines, natalizumab, vedolizumab, methotrexate (12 weeks), anti-tumor necrosis factor (TNF), ustekinumab (8 weeks), 5-aminosalicylic acid (5-ASA) (2 weeks), steroids (1 week) Willingness and capacity to significantly change diet (arm 1) Willing and able to comply with specimen collection and other study procedures, and to complete the study Exclusion Criteria: Ostomy Use of Specific Carbohydrate Diet of IBD-AID™ within 4 weeks of screening Use of prescribed probiotics within 4 weeks of screening > 20mg prednisone or equivalent Recent C. difficile colitis Pregnancy Presence of symptomatic or significant structure or history of obstruction in the past 6 months
Sites / Locations
- University of Massachusetts Chan MedicaL School
- University of Puerto RicoRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Arm1: Crohn's disease patients + DAIN
Arm 2: Crohn's disease patients no intervention
Participants will have 10 weeks of DAIN intervention (From week 1 to week 10)
Participants will continue consuming their usual diet, with no intervention