Traditional Vaginal Surgery VS Autologous Tissue in Pelvic Floor Repair (PREFAP)
Vaginal Vault Prolapse
About this trial
This is an interventional treatment trial for Vaginal Vault Prolapse focused on measuring Autologous graft, vNOTES, Pelvic organ prolapse
Eligibility Criteria
Inclusion Criteria: patients older than 18 years old with no desire to preserve fertility, POP-Q 3 or 4 stage of prolapse with indication for hysterectomy (abnormal uterine bleeding, enlarged fibrous uterus, premalignant cervical findings) Exclusion Criteria: Virginity, pregnancy, acute urinary infection were considered contraindications; malignancy, previous PID or rectal surgery. Rectovaginal endometriosis. Contraindication for general anaesthesia, pneumoperitoneum or Trendelenburg position. Previous pelvic radiotherapy
Sites / Locations
- Luka Matak MDRecruiting
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Active Comparator
Traditional surgery
vNOTES PREFAP
This group of patients will be treated with standard technique (vaginal hysterectomy with anterior and/or posterior vaginal repair) for pelvic organ prolapse .
This group of patients will be treated with vNOTES aproach using autologous graft isolated from posterior rectus fascia for pelvic organ prolapse.