Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study
Blepharitis
About this trial
This is an interventional treatment trial for Blepharitis focused on measuring Blepharitis
Eligibility Criteria
Inclusion Criteria: Male or female, aged ≥ 18 years of age. Be willing to sign the informed consent and deemed capable of complying with the requirements of the study protocol. Has blepharitis Stated willingness to comply with all study procedures and availability for the duration of the study. Exclusion Criteria: Have used lid hygiene products (e.g., lid scrubs) within 14 days of Screening or unwilling to forego the use of lid hygiene products during the study. Have initiated treatment with an ocular topical prostaglandin analogue within 30 days of Screening or have any plans to change or discontinue treatment during the study Pregnancy or lactation. Any intraocular surgery (including ocular surface surgery, cataract surgery and intravitreal injection) or periocular surgery within 60 days prior to randomization, or any planned ocular surgical procedure during the study period Have any unstable or uncontrolled, cardiac, pulmonary, renal, oncological, neurological, metabolic or other systemic condition that, in the opinion of the investigator, would possibly require the participant to seek emergent medical treatment during the course of this study. This includes, but is not limited to, unstable or uncontrolled cardiac arrhythmias, hypertension, coagulopathies, renal failure or advanced diabetes mellitus.
Sites / Locations
- Beijing Tongren Hospital
- Peking University Third Hospital
- Chongqing Aier Eye Hospital
- Xiamen Eye Center of Xiamen University
- Guangzhou Aier Eye Hospital
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- Hainan Eye Hospital
- The First Affiliated Hospital of Harbin Medical University
- Henan Provincial Eye Hospital
- Union Hospital, Tongji Medical College Huazhong University of Science and Technology
- Renmin Hospital of Wuhan University
- The Second Xiangya Hospital of Central South University
- Xiangya Hospital, Central South University
- The First Affiliated Hospital of University of South China
- Wuxi Second People's Hospital
- Eye& Ent Hospital of Fudan University
- Shanghai General Hospital
- Shanxi Provincial Eye Hospital
- Tianjin Medical University Eye Hospital
- The Second Affiliated Hospital Zhejiang University School of Medicine
- Eye Hospital, Wenzhou Medical University
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Lotilaner Ophthalmic Solution (TP-03)
Vehicle Control
Lotilaner Ophthalmic Solution (TP-03)
Vehicle Control