Cresemba® in Treating Chinese Patients With IFD Caused by Aspergillus Species or Other Filamentous Fungi
Invasive Fungal Disease
About this trial
This is an interventional treatment trial for Invasive Fungal Disease focused on measuring Isavuconazole, Invasive Aspergillus, Invasive mold
Eligibility Criteria
Inclusion Criteria: proven, probable, or possible IFD caused by Aspergillus species, Mucorales species or other filamentous fungi body weight >40 kg at screening Exclusion Criteria: either chronic aspergillosis, aspergilloma, or ABPA Advanced HIV infection with CD4 count < 200 or acquired immunodeficiency syndrome-defining condition people who are unlikely to survive 5 days or participants on mechanical ventilation severe hepatic impairment (Child-Pugh Class C) familial short QT syndrome Concomitant use of efavirenz, ritonavir, etravirine, rifampicin/rifampin, rifabutin, nafcillin, ketoconazole, or St. John's Wort in the 5 days prior to first administration of study intervention
Sites / Locations
- The First Affiliated Hospital of Bengbu Medical CollegeRecruiting
- Anhui Provincial Hospital
- The First Affiliated Hospital of USTC, Anhui Province HospitalRecruiting
- Anhui Provincial Hospital
- Peking University Third Hospital
- The First Affiliated Hospital of Guangzhou Medical UniversityRecruiting
- Guangzhou First People's HospitalRecruiting
- ZhuJiang Hospital of Southern Medical UniversityRecruiting
- Jieyang People's HospitalRecruiting
- Henan provincial people's hospital
- The Third Xiangya Hospital of Central South University
- The First Affiliated Hospital of Suzhou University
- The First Affiliated Hospital of Suzhou University
- Qilu Hospital of Shandong UniversityRecruiting
- Liaocheng people's Hospital
- Zibo Central HospitalRecruiting
- Zibo Central Hospital
- Shanghai Ninth People's Hospital
- Huashan Hospital, Fudan UniversityRecruiting
- Institute of Hematology, Chinese Academy of Medical SciencesRecruiting
- The First Affiliated Hospital Zhejiang UniversityRecruiting
- Peking University People's Hospital
- The First Affiliated Hospital of Bengbu Medical CollegeRecruiting
Arms of the Study
Arm 1
Experimental
Isavuconazole
This is a single arm study, all enrolled participants will receive the study medication.