Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study
Periodontal Diseases, Periodontal Pocket, Periodontal Bone Loss
About this trial
This is an interventional treatment trial for Periodontal Diseases focused on measuring Periodontitis, Manuka honey, Periodontal pocket depth
Eligibility Criteria
Inclusion Criteria: Patients of both genders with good systemic health; Non-smokers; Presence of at least 20 teeth; Untreated moderate to advanced generalized chronic periodontitis according to the 1999 Classification 199 , i.e., generalized stage III periodontitis according to the 2007 Classification Exclusion Criteria: Pregnant and nursing women; Antibiotics prescribed for dental or non-dental diseases 6 months before the start of the research; Systemic diseases or the use of drugs known to affect periodontal tissues, bleeding parameters; Acute oral or periodontal inflammation or infection (pericoronitis, necrotizing periodontal diseases, etc.).
Sites / Locations
- School of Dental Medicine
Arms of the Study
Arm 1
Experimental
Manuka honey
The intervention in this study was conducted in a split-mouth design, meaning that after completing the NSPT for each subject, Manuka honey was administered as an adjunct to the periodontal treatment in two randomly selected quadrants of the oral cavity around the teeth with a specially designed cannula. The cannula reached the bottom of the periodontal pocket and moved circumferentially around the tooth at 6 sites, and Manuka honey was extruded until the excess of the material was observed in the sulcus.