Maximal inspiratory mouth pressure (PImax)
Maximal inspiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Maximal inspiratory mouth pressure (PImax)
Maximal inspiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Maximal inspiratory mouth pressure (PImax)
Maximal inspiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Maximal inspiratory mouth pressure (PImax)
Maximal inspiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Feasibility: adherence from baseline (M0) to 4 months visit (M4)
The completion rate of the estimated number of training sessions over 4 months (>80% of the participants have fulfilled the prescribed treatment = good adherence). Adherence will be monitored by a patient diary, the data saved in the POWERbreathe KHP2 and, two weekly telephone- or video calls by a physiotherapist.
Feasibility: adherence from 4 months (M4) to 8 months visit (M8)
The completion rate of the estimated number of training sessions over 4 months (>80% of the participants have fulfilled the prescribed treatment = good adherence). Adherence will be monitored by a patient diary, the data saved in the POWERbreathe KHP2 and, two weekly telephone- or video calls by a physiotherapist.
Feasibility: adherence from 8 months (M8) to 12 months visit (M12)
The completion rate of the estimated number of training sessions over 4 months (>80% of the participants have fulfilled the prescribed treatment = good adherence). Adherence will be monitored by a patient diary, the data saved in the POWERbreathe KHP2 and, two weekly telephone- or video calls by a physiotherapist.
Feasibility: acceptability
The willingness to continue the training (>5 = good acceptability) assessed with a Borg Scale (0-10)
Feasibility: acceptability
The willingness to continue the training (>5 = good acceptability) assessed with a Borg Scale (0-10)
Feasibility: acceptability
The willingness to continue the training (>5 = good acceptability) assessed with a Borg Scale (0-10)
Maximal expiratory mouth pressure (PEmax)
Maximal expiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Maximal expiratory mouth pressure (PEmax)
Maximal expiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Maximal expiratory mouth pressure (PEmax)
Maximal expiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Maximal expiratory mouth pressure (PEmax)
Maximal expiratory mouth pressure in Centimeter of Water Column (cmH2O) assessed conform the European Respiratory Society/American Thoracic Society (ERS/ATS) recommendations. Reference values of Wilson et al. 1984 will be used to calculate % of predicted.
Health related quality of life
Health related quality of life will be measured with the 36-item Short Form Health Survey (SF36) for adults and the Pediatric Quality of Life Inventory (PedsQL) for children and their parents/caregivers.
Health related quality of life
Health related quality of life will be measured with the 36-item Short Form Health Survey (SF36) for adults and the Pediatric Quality of Life Inventory (PedsQL) for children and their parents/caregivers.
Health related quality of life
Health related quality of life will be measured with the 36-item Short Form Health Survey (SF36) for adults and the Pediatric Quality of Life Inventory (PedsQL) for children and their parents/caregivers.
Health related quality of life
Health related quality of life will be measured with the 36-item Short Form Health Survey (SF36) for adults and the Pediatric Quality of Life Inventory (PedsQL) for children and their parents/caregivers.
Forced vital capacity (FVC)
Forced vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Forced vital capacity (FVC)
Forced vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Forced vital capacity (FVC)
Forced vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Forced vital capacity (FVC)
Forced vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Slow vital capacity (SVC)
Slow vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Slow vital capacity (SVC)
Slow vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Slow vital capacity (SVC)
Slow vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Slow vital capacity (SVC)
Slow vital capacity in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Peak expiratory flow (PEF)
Peak expiratory flow in liters per second assessed conform the ERS/ATS recommendations. Reference values of Quanjer et al. 1993 will be used to calculate % of predicted for adults and Koopman et al. 2011 will be used to calculate % of predicted for kids.
Peak expiratory flow (PEF)
Peak expiratory flow in liters per second assessed conform the ERS/ATS recommendations. Reference values of Quanjer et al. 1993 will be used to calculate % of predicted for adults and Koopman et al. 2011 will be used to calculate % of predicted for kids.
Peak expiratory flow (PEF)
Peak expiratory flow in liters per second assessed conform the ERS/ATS recommendations. Reference values of Quanjer et al. 1993 will be used to calculate % of predicted for adults and Koopman et al. 2011 will be used to calculate % of predicted for kids.
Peak expiratory flow (PEF)
Peak expiratory flow in liters per second assessed conform the ERS/ATS recommendations. Reference values of Quanjer et al. 1993 will be used to calculate % of predicted for adults and Koopman et al. 2011 will be used to calculate % of predicted for kids.
Forced expiratory volume in 1 second (FEV1)
Forced expiratory volume in 1 second in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Forced expiratory volume in 1 second (FEV1)
Forced expiratory volume in 1 second in liters assessed conform the ERS/ATS recommendations.Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Forced expiratory volume in 1 second (FEV1)
Forced expiratory volume in 1 second in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Forced expiratory volume in 1 second (FEV1)
Forced expiratory volume in 1 second in liters assessed conform the ERS/ATS recommendations. Reference values from Quanjer et al. 2012 will be used to calculate % of predicted.
Peak cough flow (PCF)
Peak cough flow in liters per second assessed conform the ERS/ATS recommendations.
Peak cough flow (PCF)
Peak cough flow in liters per second assessed conform the ERS/ATS recommendations.
Peak cough flow (PCF)
Peak cough flow in liters per second assessed conform the ERS/ATS recommendations.
Peak cough flow (PCF)
Peak cough flow in liters per second assessed conform the ERS/ATS recommendations.
Sniff Nasal Inspiratory Pressure (SNIP)
Sniff Nasal Inspiratory Pressure in Kilopascal (kPa) assessed conform the ERS/ATS recommendations.
Sniff Nasal Inspiratory Pressure (SNIP)
Sniff Nasal Inspiratory Pressure in Kilopascal (kPa) assessed conform the ERS/ATS recommendations.
Sniff Nasal Inspiratory Pressure (SNIP)
Sniff Nasal Inspiratory Pressure in Kilopascal (kPa) assessed conform the ERS/ATS recommendations.
Sniff Nasal Inspiratory Pressure (SNIP)
Sniff Nasal Inspiratory Pressure in Kilopascal (kPa) assessed conform the ERS/ATS recommendations.
Mouth occlusion pressure at 100ms (P0.1)
Mouth occlusion pressure at 100ms during quiet breathing in Kilopascal (kPa). P0.1 is a marker of neuromuscular ventilator drive, which is independent of the patient's effort. Assessed conform the ERS/ATS recommendations. Reference values of Criee 2003 will be used to calculate % of predicted.
Mouth occlusion pressure at 100ms (P0.1)
Mouth occlusion pressure at 100ms during quiet breathing in Kilopascal (kPa). P0.1 is a marker of neuromuscular ventilator drive, which is independent of the patient's effort. Assessed conform the ERS/ATS recommendations. Reference values of Criee 2003 will be used to calculate % of predicted.
Mouth occlusion pressure at 100ms (P0.1)
Mouth occlusion pressure at 100ms during quiet breathing in Kilopascal (kPa). P0.1 is a marker of neuromuscular ventilator drive, which is independent of the patient's effort. Assessed conform the ERS/ATS recommendations. Reference values of Criee 2003 will be used to calculate % of predicted.
Mouth occlusion pressure at 100ms (P0.1)
Mouth occlusion pressure at 100ms during quiet breathing in Kilopascal (kPa). P0.1 is a marker of neuromuscular ventilator drive, which is independent of the patient's effort. Assessed conform the ERS/ATS recommendations. Reference values of Criee 2003 will be used to calculate % of predicted.
P0.1/PImax
The ratio of P0.1/PImax have been suggested as important predictor of impending respiratory muscle fatigue (work of breathing)
P0.1/PImax
The ratio of P0.1/PImax have been suggested as important predictor of impending respiratory muscle fatigue (work of breathing)
P0.1/PImax
The ratio of P0.1/PImax have been suggested as important predictor of impending respiratory muscle fatigue (work of breathing)
P0.1/PImax
The ratio of P0.1/PImax have been suggested as important predictor of impending respiratory muscle fatigue (work of breathing)
Medical Research Council (MRC) dyspnea scale
This scale measures perceived respiratory disability.
Medical Research Council (MRC) dyspnea scale
This scale measures perceived respiratory disability.
Medical Research Council (MRC) dyspnea scale
This scale measures perceived respiratory disability.
Medical Research Council (MRC) dyspnea scale
This scale measures perceived respiratory disability.
Respiratory infections
Respiratory infection frequency (based on the need for antibiotics and/or hospitalization).
Respiratory infections
Respiratory infection frequency (based on the need for antibiotics and/or hospitalization).
Respiratory infections
Respiratory infection frequency (based on the need for antibiotics and/or hospitalization).
Respiratory infections
Respiratory infection frequency (based on the need for antibiotics and/or hospitalization).
Adverse Events
Adverse Events
Adverse Events
Adverse Events Adverse Events coded according to the introductory guide MedDRA version 21.0
Dyspnea immediately after lung function measure and after each training session
Assesses with a Borg scale ranging from 0-10.
Dyspnea immediately after lung function measure and after each training session
Assesses with a Borg scale ranging from 0-10.
Dyspnea immediately after lung function measure and after each training session
Assesses with a Borg scale ranging from 0-10.
Dyspnea immediately after lung function measure and after each training session
Assesses with a Borg scale ranging from 0-10.
Dyspnea immediately after lung function measure and after each training session
Assesses with a Borg scale ranging from 0-10.