Sentinel NOSE Study: Prospective Registration Study on the Sentinel Node Procedure for Bulky Squamous Cell Carcinoma of the Nasal Vestibule.
Squamous Cell Carcinoma of the Nasal Vestibule
About this trial
This is an interventional diagnostic trial for Squamous Cell Carcinoma of the Nasal Vestibule focused on measuring nasal vestibule, sentinel node, nodal metastases
Eligibility Criteria
Inclusion Criteria: Aged 18 years or older. WHO performance score of 0, 1 or 2. Newly diagnosed T1 or T2 squamous cell carcinoma of the nasal vestibule. Tumor diameter ≥1.5 cm and/or tumor volume ≥1.5cm3 Clinically negative neck (N0). Patients planned to undergo curative treatment. Patient provided written informed consent Exclusion Criteria: Prior allergic reaction to either indocyanide green, 99m-Technetium nanocolloid or human colloidal albumin. Pregnancy. Previous surgery or radiotherapy of the neck. Concurrent secondary head-and-neck tumor. Unable to provide informed consent
Sites / Locations
- Anthoni van Leeuwenhoekhuis
- Radboud UMCRecruiting
Arms of the Study
Arm 1
Experimental
sentinel node procedure
Participants will indergo the standard treatment for their disease ( i.e. brachytherapy) but a sentinel node procedure will be added to their treatment