At Home Gamma tACS in Alzheimer's Disease (tACS@Home) (tACS@Home)
Alzheimer Disease
About this trial
This is an interventional treatment trial for Alzheimer Disease
Eligibility Criteria
Inclusion Criteria for the Patient: Mild Alzheimer's disease (CDR 0.5 - 1) Exclusion Criteria for the Patient: Cerebrovascular disorders Previous stroke Hydrocephalus Intra-cranial mass documented by MRI History of traumatic brain injury or other neurological diseases Serious medical illness other than AD History of seizures Pregnancy Metal implants in the head (except dental fillings) Electronic implants (i.e. pace-maker, implanted medical pump) Age <18 years Inclusion Criteria for the Caregiver: Age > 18 years Compliance in participation in training on the use of the therapeutic device Mini-Mental State Examination >26/30
Sites / Locations
- ASST Spedali Civili di BresciaRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Real tACS - Real tACS
Sham tACS - Real tACS
42 sessions of 40 Hz transcranial alternating current stimulation (5 days/week for 9 weeks) followed by an open-label 42 sessions of 40 Hz transcranial alternating current stimulation (5 days/week for 9 weeks).
42 sessions of sham stimulation (5 days/week for 9 weeks) followed by an open-label 42 sessions of 40 Hz transcranial alternating current stimulation (5 days/week for 9 weeks).