Impact of Dietary Fiber Supplementation on Colonic Mucosal Microbiome
Benign Colorectal Neoplasm, Non-Neoplastic Anal Disorder
About this trial
This is an interventional supportive care trial for Benign Colorectal Neoplasm
Eligibility Criteria
Inclusion Criteria: Age >= 18 years Ability to understand and the willingness to sign a written informed consent document Patients who present with a chief complaint of a benign anorectal pathology including hemorrhoids, anal fissures, and anal fistulas without underlying conditions such as cancer or Crohn's disease Patients who had a colonoscopy within the past 2 years Exclusion Criteria: Patients with an active malignancy, Crohn's disease, ulcerative colitis, and immunosuppressed patients. Patients with hereditary colon cancer syndrome including Lynch syndrome or Familial Adenomatous Polyposis (FAP) Patients with a prior history of total or partial colon resection. Colorectal pathology such as polyps or cancer
Sites / Locations
- OHSU Knight Cancer InstituteRecruiting
Arms of the Study
Arm 1
Experimental
Supportive care (dietary fiber, proctoscopy or anoscopy with biopsy)
Patients receive dietary fiber PO on study. Patients undergo proctoscopy or anoscopy with biopsy on study and during follow-up.